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All Journal Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) INDRA: Jurnal Pengabdian kepada Masyarakat
Amir, Muhammad Nur
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Veterinary

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Aktivitas Antibakteri Ekstrak Kelopak Bunga Rosella Terenkapsulasi Maltodekstrin dan Sinergitasnya dengan Isoniazida dan Rifampisin Terhadap Mycobacterium tuberculosis H37rv: Antibacterial Activity of Rosella Calyx Extract Encapsulated by Maltodextrin and Its Sinergity with Isoniazid and Rifampicin Against Mycobacterium tuberculosis H37rv N. Djide, Nana Juniarti; Djide, M.Natsir; Amir, Muhammad Nur; Sartini, Sartini
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 5 No. 2 (2019): (October 2019)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (266.257 KB) | DOI: 10.22487/j24428744.2019.v5.i2.12946

Abstract

First-line drugs (Isoniazid and Rifampicin) for the treatment of tuberculosis are known to have experienced resistance to Mycobacterium tuberculosis. The aim of this study was to determine the minimum inhibitory concentration (MIC) of maltodextrin encapsulated rosella calyx extract and its ability to provide a synergistic effect with Isoniazid (INH) and Rifampicin (RIF) on M. tuberculosis R37rv. Rosella calyxs were macerated using 50% ethanol and encapsulated using maltodextrin. Antibacterial activity was carried out by determining MIC value using Microscopic Observation and Direct Susceptibility (MODS) method. The synergistic effect was carried out by calculating the Fractional Inhibition Concentration Index (FICI). The results showed that this extract was able to inhibit M. tuberculosis H37rv with MIC of 10 mg/ ml. The FICI value of the combination of extract with INH and rifampicin was obtained 1.25. This showed that rosella calyx extract is not synergistic with INH and rifampicin, might be due to rosella calyx extract has an antibacterial effect with a different mechanism with INH and Rifampicin.
Pemberdayaan unit Center of Excellence Fakultas Farmasi UNHAS melalui produksi produk inovatif minuman instan Ginger Creamy Plus Sartini, Sartini; Djide, Nana Juniarti Natsir; Nainu, Firzan; Amir, Muhammad Nur; Mangilep, Muhammad Agung Ady
INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 6 No. 2 (2025): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/indra.v6i2.592

Abstract

One of the key performance indicators (KPI/IKU) of the Ministry of Higher Education and Science and Technology is IKU 5: community recognition of lecturers' research outcomes. The PPUPIK-UNHAS community service program aimed to promote lecturers' innovative products for broader public recognition. In this community service initiative, we introduced an instant ginger-based beverage (Zingiber officinale), developed by modifying the traditional Sarabba drink with bee pollen. Ginger is well known for its health benefits, including antioxidant properties, improved digestion, pain and inflammation relief, enhanced immunity, and preventing nausea and vomiting. Including bee pollen—rich in amino acids, flavonoids, B vitamins, and minerals—further enhances the drink's functional health effects. The resulting product, Ginger Creamy Plus, was formulated as an instant drink, with each sachet containing 1.2 g of ginger and 0.3 g of bee pollen. This innovation has been registered with HAKI under the simple patent category and has received a P-IRT business permit. It is expected to be commercialized on an industrial scale in collaboration with UNHAS business units and registered with the Food and Drug Supervisory Agency.
Anthelmintic Activity of Jatropha (Jatropha curcas linn) Leaf Extract Against Ascaridia galli Worms In Vitro Jamaluddin, Abdul Wahid; Ainun, Hasri; Ris, Adryani; Amir, Muhammad Nur
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 6 No.1, JANUARY 2022
Publisher : Hasanuddin University

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Abstract

Ascariasis is an intestinal worm disease caused by Ascaridia galli. This disease can attack the small intestine and cause a decrease in productivity of local breed chickens. Worm infections in chickens can be suppressed by taking precautions and treatment measures such as improving the management of the cage and providing anthelmintic. Medicinal plants that can be used as an alternative anthelmintic are jatropha leaves (Jatropha curcas linn) which contain secondary metabolites such as alkaloids, saponins, tannins, phenolics, flavonoids, triterpenoids, steroids, and glycosides. The study aims to determine the anthelmintic activity of Jatropha leaf extract against Ascaridia galli worms. 75 samples of Ascaridia galli worms were taken from chicken intestines in traditional markets. This research was conducted in vitro with five treatments consisting of one positive control group using Levamisole, one negative control group with 0.5% NaCMC, and three groups of Jatropha leaf extract (JLE) with concentrations of 10%, 15% and 20 %. The results of the study showed that jatropha leaf extract at a concentration of 20% gave a better anthelmintic effect compared with administration of Levamisole as a positive control (+) and jatropha leaf extract had LC50 and LT50 at concentrations of 5.49% and 96.006 minutes.
Co-Authors Abdul Wahid Jamaluddin Adryani Ris Ainun, Hasri Djide, Nana Juniarti Natsir Firzan Nainu M.Natsir Djide Mangilep, Muhammad Agung Ady Sartini Sartini