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All Journal VALENSI Warta Perkaretan
Hidayat, Ade Sholeh
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Materials Science & Nanotechnology

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PENGARUH JENIS KARET TERHADAP KETAHANAN SODIUM HIDROKSIDA UNTUK APLIKASI RUBBER LINING Wahyu Tri Utami; Arti, Dewi Kusuma; Indriasari, Indriasari; Fidyaningsih, Riastuti; Hidayat, Ade Sholeh; Amry, Akhmad; Susanto, Herri; Wisojodharmo, Lies; Idvan, Idvan; Iskandar, M Soleh
Warta Perkaretan Vol. 42 No. 1 (2023): Volume 42, Nomor 1, Tahun 2023
Publisher : Pusat Penelitian Karet - PT. Riset Perkebunan Nusantara

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Abstract

Rubber lining adalah metode yang digunakan untuk melindungi permukaan interior atau eksterior pipa, tangki, bejana, dan aplikasi serupa lainnya dari korosi. Penelitian ini menggunakan beberapa jenis karet sebagai variabel penelitian, antara lain Karet Alam RSS 1 (RL1), Ethylene Propylene Diene Monomer (EPDM 4869 (RL2)), Styrene Butadiene Rubber (RL3), Isobutene Isoprene Rubber (RL4). Penelitian ini bertujuan untuk mengetahui pengaruh jenis karet terhadap ketahanan sodium hidroksida pada aplikasi rubber lining. Untuk mengetahui sifat-sifat sampel, dilakukan beberapa pengujian mekanik meliputi uji pengembangan, uji rheologi, kekuatan tarik, ketahanan kikis, uji kekerasan. Hasil karakterisasi menunjukkan bahwa formulasi yang optimum untuk pelapis karet tahan basa adalah formulasi dengan bahan utama Styrene Butadiene Rubber .
Two Sesquiterpenes from n-Hexane Fraction of Curcuma soloensis Rhizomes and Their Antimicrobial Activities Diastuti, Hartiwi; Asnani, Ari; Lestari, Puji; Astuti, Teni; Nurmalia, Naela; Hidayat, Ade Sholeh
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 10, No. 1, May 2024
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v10i1.36613

Abstract

Curcuma soloensis is one of the medicinal plants that has the potential to be a source of bioactive compounds. The antimicrobial study of the bioactive compounds from C. soloensis was still limited. This study aimed to isolate the bioactive compounds from C. soloensis rhizomes and to evaluate their potential as antimicrobial agents. C. soloensis rhizome extraction was done using the maceration method with acetone and then fractionated with n-hexane: methanol (1:1). The compounds were separated and purified using vacuum liquid chromatography and radial chromatography. The structure of the isolated compounds was determined using the nuclear magnetic resonance (1H and 13C NMR) spectroscopy analysis and comparison with literature data. Antimicrobial activity assays of the extract, n-hexane fraction, and isolated compounds were carried out by microdilution methods against Escherichia coli, Staphylococcus aureus, Candida albicans, and Malaszezia furfur. Two bioactive compounds from the n-hexane extract of C. soloensis rhizome have been isolated: ar-curcumene and ar-turmerone. Antimicrobial test results on acetone extract, n-hexane fraction, and isolated compounds showed that ar-turmerone had the highest activity against S. aureus with a MIC value of 15.6 μg / mL. In comparison, ar-curcumene showed the same activity against all test microbes with a MIC value of 62.5 μg / mL.  This study showed that secondary metabolite compounds of C. soloensis rhizomes have the potential to be developed as antimicrobial agents.
Co-Authors Amry, Akhmad Ari Asnani Astuti, Teni Dewi Kusuma Arti Fidyaningsih, Riastuti Hartiwi Diastuti Herri Susanto Idvan, Idvan Indriasari, Indriasari Iskandar, M Soleh Nurmalia, Naela PUJI LESTARI Wahyu Tri Utami Wisojodharmo, Lies