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All Journal Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia PROSIDING SEMINAR KIMIA Jurnal Ilmiah Manuntung Jurnal Riset Kefarmasian Indonesia FASKES : Jurnal Farmasi, Kesehatan, dan Sains Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Warnida, Husnul
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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FORMULASI DAN EVALUASI KRIM EKSTRAK BAWANG TIWAI (Eleutherine bulbosa) Warnida, Husnul; Nurhasnawati, Henny
Jurnal Ilmiah Manuntung Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (137.209 KB) | DOI: 10.51352/jim.v3i1.93

Abstract

Exposure of the skin to ultraviolet (UV) radiation from the sun has various adverse effects, photoaging and skin cancer are of great concern. The ability of botanical antioxidants for prevention of photocarcinogenesis and photoaging had been widely known. Bawang tiwai (Eleutherine bubosa) is traditionally used by the native people of Kalimantan for cancer treatment. The ethanolic extract of bawang tiwai originated from Banjarbaru district, South Kalimantan had strong antioxidant activity. The objective of the study was to formulate Eleutherine bulbosa extract into cream and evaluate its scavenging activity. Antioxidant activity of Eleutherine bulbosa cream was assessed by 2-diphenyl-1-picrylhydrazyl (DPPH) method. The Eleutherine bulbosa extract was incorporated into five cream formulas in varied concentration of emulsifying wax and cetyl alcohol. Evaluation of cream including physical appearance, pH, viscosity, stability, and microbial growth test. The result showed that Eleutherine bulbosa cream has antioxidant activity and good physicochemical quality
FORMULASI GEL PATI BENGKUANG (Pachyrhizus erosus (L.) Urb.) DENGAN GELLING AGENT METILSELULOSA Warnida, Husnul
Jurnal Ilmiah Manuntung Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (248.583 KB) | DOI: 10.51352/jim.v1i2.23

Abstract

Bengkuang roots (Pachyrhizus erosus (L.) Urb.)  empirically have been used as cosmetics materials, primarily as sun screen and whitening agent. Bengkuang roots posses 6 compound which have tyrosinase inhibitory activities. Commercially, bengkuang roots available as whitening cream and lotion but those dosage forms are not suitable for oily skin. In this study the gel was formulated with varying methylcellulose (4% and 5%) as gelling agent. The evaluation included stability, organoleptic, pH, homogeneity, and spreading test. Formula A (4% methylcellulose) meets all physical requirements of gel. The result of acceptability (hedonic test. showed the most acceptance formula was formula A (4% methylcellulose).
FORMULA DAN EVALUASI GEL PEMBERSIH TANGAN EKSTRAK BAWANG TIWAI (Eleutherine bulbosa (Mill.) Urb) Sukawaty, Yullia; Apriliana, Anita; Warnida, Husnul
Jurnal Ilmiah Manuntung Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (197.587 KB) | DOI: 10.51352/jim.v3i1.94

Abstract

Bawang tiwai (Eleutherine bulbosa (Mill.) Urb.) acts as an antibacterial because it contains a class of alkaloids, flavonoids, saponins, tannins, glycosides, triterpinoida / steroid, anthraquinone glycosides.Bawang tiwai onions can be used as an antibacterial active ingredient formulated in a gel hand sanitizer. The purpose of this study to determine the effect of varying concentrations of alcohol on the physical properties of gel preparation and inhibition of E.coli bacteria which are formulated in the form of a gel hand sanitizer bawang tiwai extract. Research conducted on fomula gel hand sanitizer bawang tiwai extract with various concentrations of alcohol F1 0%, F2 10%, F3 20%, F4 60% include (organoleptic, homogeneity, pH, dispersive power, consistency and viscosity) and continued with test inhibition of E. coli using disc diffusion method (Kirby-Bauer) in F1 0%, 10% F2, F3 20%, K (-) 60% and K (+) Triclosan 0.1%. Data were analyzed with SPSS 16.0 using Kruskal Wallis test with a level of 95%, α = 0.05. Gel hand sanitizer contains bawang tiwai extract 20% meets the requirements of the physical stability and have antibacterial inhibition of E. Coli
STABILITAS DAN AKTIVITAS GEL EKSTRAK BULBUS BAWANG TIWAI (Eleutherine americana (Mill.) Urb.) SEBAGAI ANTI ACNE Warnida, Husnul; Sukawaty, Yullia; Mega, Mega
Jurnal Ilmiah Manuntung Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (77.652 KB) | DOI: 10.51352/jim.v1i1.19

Abstract

awang Tiwai has an antibacterial activity toward some microorganisms e.g. Staphylococcus epidermidis dan Propionibacterium acne, two acne related bacteria. Bawang Tiwai extract 1% and 2% were formulated into gel (no oil content, because oil could make the acne worse) with carbomer 940 as gelling agent. Physical stability of bawang tiwai gel was evaluated included stability, organoleptic, pH, homogeneity, viscosity, consistency, spreading test, and activity toward Staphylococcus epidermidis.  The result showed that all formulas are stable after 7 days. The test results of antibacterial activity gel are 17,24 mm dan gel 19,75 mm to gel 1% dan 2% respectively.
PERSEPSI MASYARAKAT TERHADAP DAMPAK KESEHATAN DARI AKTIVITAS PENAMBANGAN BATUBARA DI KAMPUNG TASUK KABUPATEN BERAU Mursyidin, Musyidin; Warnida, Husnul
Jurnal Ilmiah Manuntung Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (323.241 KB) | DOI: 10.51352/jim.v2i2.56

Abstract

Mining is an ancient occupation, long recognized as being arduous and liable to injury and disease. Coal mining carried dangers from exposure to noise, heat, and airborne dusts, causing many associated diseases. Respiratory diseases caused by coal mine dust are pneumoconiosis, chronic bronchitis, and emphysema. The process of coal mining involves the discharge of huge amount of effluent into the surface water. Effluent from coal mine contains high load of TSS, TDS, calcium carbonate and heavy metals accumulates in water, soil, sediment and living organism. Coal mining has long been established in East Kalimantan. This paper explores the public perceptions of the health and environmental impact of opencast coal mining in Kampung Tasuk, Gunung Tabur, Regency of Berau, East Kalimantan. The obtained result may be used as an input to formulate and redesign the community development program of coal mining company in Berau. The public perception of coal mining activity in kampung Tasuk was dissastified with costumer satisfaction index 58.1
FORMULASI EKSTRAK ETANOL GAMBIR (Uncaria gambir Roxb.) DALAM BEDAK ANTI JERAWAT Warnida, Husnul; Masliyana, Agustiani; Sapri, Sapri
Jurnal Ilmiah Manuntung Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (88.713 KB) | DOI: 10.51352/jim.v2i1.53

Abstract

Acne occurs due to blockage of pilosebaseus (oil glands) and inflammation causing by Propionibacterium acne, Staphylococcus epidermidis and Staphylococcus aureus. The purpose of the study was to test the antibacterial activity of gambir (Uncaria gambier Roxb.) ethanol extract toward Staphylococcus epidermidis and to formulate gambir ethanol extract into a loose powder dosage form that meets the standards of physical powder quality. Gambir was macerated with 95% ethanol. Activity of gambir ethanol extract against Staphylococcus epidermidis was tested by diffusion method using varying concentrations 3%, 6% and 9% of gambir etanol extract. Afterward, gambir ethanol extract formulated into powder. Analyze of powder physical properties including organoleptic test, homogeneity and particle size distribution. The results showed gambirethanol extract 3%, 6%, 9% has inhibition zone diameter 3.6 mm, 4.2 mm, and 6.8 mm respectively. Gambir ethanol extract powder has a homogeneous, fine size with a light brown color and a distinctive gambir aroma. The average particle size of the powder is 236.17 μm
PERBANDINGAN METODE EKSTRAKSI EKSTRAK UMBI BAWANG RAMBUT (Allium chinense G.Don.) MENGGUNAKAN PELARUT ETANOL 70% TERHADAP RENDEMEN DAN SKRINING FITOKIMIA Supomo, Supomo; Warnida, Husnul; Said, Bagus Moch
Jurnal Riset Kefarmasian Indonesia Vol 1 No 1 (2019): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (445.411 KB) | DOI: 10.33759/jrki.v1i1.15

Abstract

Allium chinense are plants that contain bioactive compounds such as alkaloids, flavonoids, and saponins. The rendement of an extract may be affected by the extraction mentod used. This study aims to determine the effect of maseration and digestion extraction method on rendemen and identification of secondary metabolite in the extract of the hair onion bulbs. Research conducted is an experimental study. The samples used were hair bulbs obtained in Kota Bangun, East Kalimantan, extracted wiyh 2 extraction methods of maceration and digestion using ethanol 70% solvent and done as much as 3 times replication. Identification of secondary metabolite compounds was performed by phytochemical screening including test of alkaloids, flavonoids, saponins, tannins, and steroids. From the test data is processed by statistical analysis. The result of rendement with 3 times replikation of digesti mentod obtained by 20,02 gram, 19,03 gram, and 19,17 gram. While the maseration method obtained for 12,38 grams, 12,45 grams, and 15,91 grams. So there are differences between the results of the results of digestion mentod and maseration mentod. Based on phytochemical screening tets showed that the thick extract of hair onion bulbs contain compounds alkaloids, flavonoids, and saponins.
PERBANDINGAN FISIK FORMULA LIPSTIK DENGAN BASIS LEMAK TENGKAWANG (ILLIPE BUTTER) DAN LEMAK COKLAT (COCOA BUTTER) Warnida, Husnul; Sukawaty, Yullia; Ardhita, Fazri Wisnu
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (241.004 KB)

Abstract

Illipe butter and cacao butter have alike physical characteristic. Hence, illipe butter is one of CBS (cacao butter substitute) in food industry. The studi aims to compare the physical properties of illipe butter based lipstick with cacao butter based lipstick. Illipe butter in the study is a vegetable fat from the nut of Shorae mecistopteryx, it has a melting point of 29 ° C. The study was conducted at Pharmaceutical Technology Laboratory of Stikes Samarinda. Lipstick bases consist of illipe butter, cacao butter, carnauba wax, beeswax, lanolin and castor oil. Physical evaluation of lipstick includes homogeneity test, pH test, meting point test, hardness test, patch test, and sensory evaluation. The results showed that all lipstick formulas were homogeneous, stable, and no discoloration during 14 days. The average pH of all lipstick formulas is 5.9. Melting point of illipe buteer based lipstick is 58-59 ° C and 59-60° on cocoa butter based lipstick. Illipe butter brown fat base. Hardness level of illipe butter based lipstick is 433-833 grams, while cocoa butter based lipstick has a hardness level more than 1000 grams. Panelists in sensory evaluation preferred illipe butter based lipstick.  
AKTIVITAS DAN STABILITAS FISIK LOSION TABIR SURYA DARI EKSTRAK DAUN RAMBAI (Sonneratia caseolaris (L.)engl.) Warnida, Husnul; Ardita, Ardita; Nurhasnawati, Henny; Sukawaty, Yullia
PROSIDING SEMINAR KIMIA Vol 2 No 2 (2024): Prosiding SNKT III 2023
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Long-term, intense sun exposure can cause erythema and sunburn, as well as premature aging and skin cancer. For generations, the people of the Banjar tribe of Borneo have applied a wet paste of Sonneratia caseolaris leaves mixture on the skin when undertaking tasks in the hot sun. The Sonneratia caseolaris tree is a mangrove plant that grows on river banks throughout the Borneo Island. The study aims to formulate Sonneratia caseolaris leaves ethanol extract into a stable lotion and test its efficacy as a sunscreen. Sonneratia caseolaris leaves were macerate with 70% ethanol, and the sunscreen activity of the extract was examined in vitro with a UV-visible spectrophotometer, and then formulated into a lotion dosage form. Organoleptic and homogeneity observations, pH measurements, viscosity measurements, and spreadability measurements were all performed on the lotion. Following that, the lotion sunscreen activity of was tested in vitro. The Sonneratia caseolaris extract sunscreen lotion has met the requirements of organoleptic, homogeneity, pH, viscosity, and spreadability tests. Sunscreen lotion with 2.5% Sonnerata caseolaris extract classified as standard suntan. Sonneratia caseolaris extract of Borneo has the potential to develop as a raw material for herbal cosmetics. Keywords : Sonneratia caseolaris, mangrove, lotion, sunscreen, suntan
Penetapan Kadar Flavonoid Total Ekstrak Etanol Kulit Buah Labu Kuning (Cucurbita moschata) Berdasarkan Perbedaan Konsentrasi Pelarut Secara Spektrofotometri UV-Vis ilham, ilham; Supriningrum, Risa; Warnida, Husnul
Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia Vol 25, No 1 (2024): CHEMICA
Publisher : Jurusan Kimia FMIPA UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/chemica.v25i1.59074

Abstract

ABSTRAKKulit labu kuning ( Cucurbita moschata ) yang selama ini dianggap sebagai limbah ternyata memiliki manfaat antara lain sebagai antibakteri, antioksidan, karena senyawa metabolit sekunder yang dikandungnya. Salah satu senyawa metabolit sekundernya adalah flavonoid. Penyarian senyawa aktif dalam bahan alam dapat dipengaruhi oleh konsentrasi pelarut. Tujuan penelitian ini adalah mengetahui kadar flavonoid total ekstrak etanol kulit buah labu kuning berdasarkan perbedaan konsentrasi pelarut etanol. Tahapan penelitian meliputi penentuan tanaman, pengumpulan bahan baku, pembuatan simplisia, penetapan kadar flavonoid total secara spektrofotometri UV-Vis. Variabel bebas pada penelitian ini adalah variasi konsentrasi etanol 70% dan 95%, variabel ikatan berupa kadar flavonoid total, variabel kontrol berupa metode ekstraksi, tempat pengambilan sampel. Analisis data yang digunakan adalah analisis deskriptif. Hasil penelitian menyatakan persen rendemen ekstrak etanol 70% dan 95%, masing-masing adalah 13,68% dan 15,54%. Kadar flavonoid total dari ekstrak etanol 70% dan 95%, masing-masing sebesar 1,1931% ± 0,0810; dan 1,2045% ± 0,0854. Sehingga dapat disimpulkan bahwa konsentrasi pelarut etanol berpengaruh terhadap kadar rendemen dan ekstrak flavonoid kulit buah labu kuning.Kata kunci : Cucurbita moschata , flavonoid, konsentrasi pelarut, spektrofotometri UV-Vis. ABSTRACTThe skin of pumpkin (Cucurbita moschata) which has been considered as waste so far has benefits such as antibacterial, and antioxidant, because of the secondary metabolites it contains. One of the secondary metabolites is flavonoids. The Extraction of active compounds in natural products can be affected by solvent concentration. The purpose of this study was to determine the total flavonoid content of the ethanol extract of pumpkin peel based on differences in ethanol solvent concentration. The stages of the research included plant determination, raw material collection, simplicia manufacture, extraction by maceration with variations in ethanol concentration, flavonoid phytochemical screening, and determination of total flavonoid content by UV-Vis spectrophotometry. The independent variable in this study was the variation of 70% and 95% ethanol concentration, the dependent variable was the total flavonoid content, and control variable was the extraction method, where the sample was taken. The data analysis used is descriptive analysis. The results of the study stated that the percent yield of 70% and 95% ethanol extract were 13.68% and 15.54%, respectively. The total flavonoid content of 70% and 95% ethanol extract, respectively, were 1.1931% ± 0.0810, 1.2045% ± 0.0854. So it can be concluded that the concentration of ethanol solvent affects the yield and flavonoid levels of pumpkin peel extract.Keywords : Cucurbita moschata, flavonoids, solvent concentration, UV-Vis spectrophotometry.
Co-Authors Anita Apriliana, Anita Ardhita, Ardhita Ardhita, Fazri Wisnu Ardita, Ardita Eka Siswanto Syamsul Handayani, Sri Endah Henny Nurhasnawati Ilham Ilham Masliyana, Agustiani Mega, Mega Mursyidin, Musyidin Pertiwi, Sari Putri Risa Supriningrum Said, Bagus Moch sapri sapri Sukawaty, Yullia Supomo Supomo