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Serum total protein and albumin levels among malnourished elementary-aged children East Nusa Tenggara, Indonesia Tangkelangi, Marni; Djami, Supriati Wila; Bia, Michael Bhadi; Astuti, Aldiana
Public Health of Indonesia Vol. 8 No. 4 (2022): October - December
Publisher : YCAB Publisher & IAKMI SULTRA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v8i4.643

Abstract

Background: School-aged children between 6-12 years are a vulnerable group that could be affected by malnutrition, which may cause growth failure and affect their school achievement. East Nusa Tenggara, Indonesia, is known as the province with the highest cases of malnutrition. Objective: This study aimed to determine serum total protein and albumin levels among malnourished elementary-aged children. Serum total protein and albumin are biochemical parameters that give valuable data due to malnutrition. Methods: This study employed a case-control design. Purposive sampling was used to select the samples with a total of 90 children aged 6 – 12 years, of which 45 were assigned to a case group and a control group. The children’s blood was collected and analyzed using Riele Photometer 5010. The Biuret method was applied for total protein and bromocresol green for albumin serum. Independent sample t-test with a significant value <0.05 was used to determine the difference between mean total protein and albumin levels. Results: The percentage of low total protein levels in malnourished children was 36%, and the percentage of low albumin levels was 27%. The mean level of total protein and albumin was found to be lower in malnourished than in well-nourished children, 6.324±1.1748 g/dL vs. 7.047±0.6330 g/dL (p = <0.001), and 3.927 g/dL±0.7779 g/dL vs. 4.242 g/dL±0.5272 (p = 0.016), respectively. Conclusion: There were significant differences in total protein and albumin serum among malnourished and well-nourished children. The results may serve as basic information for further studies or to create an intervention to reduce malnutrition.
Analisis Perbedaan Nilai Hematokrit pada Penderita Hipertensi Derajat Satu dan Derajat Dua Djami, Supriati Wila; Tangkelagi, Marni; Bria, Meliance; Loaloka, Meirina Sulastri
Jaringan Laboratorium Medis Vol 6, No 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.10594

Abstract

Blood pressure is the pressure exerted by blood against the walls of blood vessels and is generated by the pressure of blood against the walls of arteries when the blood is pumped from the heart to the tissues. The amount of pressure varies depending on the blood vessels and heart rate. Hypertension is a non-communicable disease that triggers health problems that occur throughout the world. Kupang Regency is one of the districts with the highest cases of hypertension in NTT province with 1,582 cases. Hypertension is closely related to hemoglobin levels, hematocrit values and erythrocyte counts. There is a significant positive relationship between hematocrit values and diastolic blood pressure. Increased blood pressure has a significant positive relationship between hemoglobin levels, hematocrit values and erythrocyte counts. Apart from that, factors that influence hypertension with hemoglobin levels, hematocrit values and erythrocyte counts are age, gender, circulating fibrinogen and red blood cell aggregation. The aim of this research is to determine the difference in hematocrit values in sufferers of grade one and degree two hypertension. This research uses a cross-sectional analytical research design based on primary data originating from examination results in Bone Village, Nekamese District, Kupang Regency in April 2023 which meets the research sample criteria. Sampling for this research was determined using the Purposive Sampling technique. The research respondents were 30 hypertension sufferers in Bone Village, Nekamese District, Kupang Regency. Research on blood pressure and hematocrit values was carried out on all respondents. The results showed that hypertension sufferers consisted of 5 (17%) men and 25 (83%) women with the highest age of hypertension sufferers being 56 years old, 24 people (80%). There were 9 (30%) people suffering from grade 1 hypertension and 21 (70%) people suffering from degree 2 hypertension with the hematocrit value of most hypertensive sufferers still within normal limits, 18 (60%) and low hematocrit values as many as 12 (40%). The results of this study were processed using SPSS software with Mann-Whitney Test analysis and presented descriptively regarding the analysis of hematocrit values in sufferers of degree one and degree two hypertension. The results of statistical analysis show p-value 0.05, which means there is no significant difference between variables and vice versa. The results of the study showed that there was no difference in hematocrit values in sufferers of degree one and degree two hypertension with a value of p=0.295. In this study, hypertension sufferers generally had normal hematocrit values, but in second-degree hypertension sufferers the hematocrit values tended to be low.
Analisis Perbedaan Nilai Hematokrit pada Penderita Hipertensi Derajat Satu dan Derajat Dua Djami, Supriati Wila; Tangkelagi, Marni; Bria, Meliance; Loaloka, Meirina Sulastri
Jaringan Laboratorium Medis Vol. 6 No. 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.10594

Abstract

Blood pressure is the pressure exerted by blood against the walls of blood vessels and is generated by the pressure of blood against the walls of arteries when the blood is pumped from the heart to the tissues. The amount of pressure varies depending on the blood vessels and heart rate. Hypertension is a non-communicable disease that triggers health problems that occur throughout the world. Kupang Regency is one of the districts with the highest cases of hypertension in NTT province with 1,582 cases. Hypertension is closely related to hemoglobin levels, hematocrit values and erythrocyte counts. There is a significant positive relationship between hematocrit values and diastolic blood pressure. Increased blood pressure has a significant positive relationship between hemoglobin levels, hematocrit values and erythrocyte counts. Apart from that, factors that influence hypertension with hemoglobin levels, hematocrit values and erythrocyte counts are age, gender, circulating fibrinogen and red blood cell aggregation. The aim of this research is to determine the difference in hematocrit values in sufferers of grade one and degree two hypertension. This research uses a cross-sectional analytical research design based on primary data originating from examination results in Bone Village, Nekamese District, Kupang Regency in April 2023 which meets the research sample criteria. Sampling for this research was determined using the Purposive Sampling technique. The research respondents were 30 hypertension sufferers in Bone Village, Nekamese District, Kupang Regency. Research on blood pressure and hematocrit values was carried out on all respondents. The results showed that hypertension sufferers consisted of 5 (17%) men and 25 (83%) women with the highest age of hypertension sufferers being > 56 years old, 24 people (80%). There were 9 (30%) people suffering from grade 1 hypertension and 21 (70%) people suffering from degree 2 hypertension with the hematocrit value of most hypertensive sufferers still within normal limits, 18 (60%) and low hematocrit values as many as 12 (40%). The results of this study were processed using SPSS software with Mann-Whitney Test analysis and presented descriptively regarding the analysis of hematocrit values in sufferers of degree one and degree two hypertension. The results of statistical analysis show p-value > 0.05, which means there is no significant difference between variables and vice versa. The results of the study showed that there was no difference in hematocrit values in sufferers of degree one and degree two hypertension with a value of p=0.295. In this study, hypertension sufferers generally had normal hematocrit values, but in second-degree hypertension sufferers the hematocrit values tended to be low.