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All Journal Public Health of Indonesia Jurnal Sehat Mandiri ANJANI Journal (Medical Science & Healthcare Studies) West Science Social and Humanities Studies Journal of World Future Medicine, Health and Nursing Jurnal Info Kesehatan
Astuti, Aldiana
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Energy Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Serum total protein and albumin levels among malnourished elementary-aged children East Nusa Tenggara, Indonesia Tangkelangi, Marni; Djami, Supriati Wila; Bia, Michael Bhadi; Astuti, Aldiana
Public Health of Indonesia Vol. 8 No. 4 (2022): October - December
Publisher : YCAB Publisher & IAKMI SULTRA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v8i4.643

Abstract

Background: School-aged children between 6-12 years are a vulnerable group that could be affected by malnutrition, which may cause growth failure and affect their school achievement. East Nusa Tenggara, Indonesia, is known as the province with the highest cases of malnutrition. Objective: This study aimed to determine serum total protein and albumin levels among malnourished elementary-aged children. Serum total protein and albumin are biochemical parameters that give valuable data due to malnutrition. Methods: This study employed a case-control design. Purposive sampling was used to select the samples with a total of 90 children aged 6 – 12 years, of which 45 were assigned to a case group and a control group. The children’s blood was collected and analyzed using Riele Photometer 5010. The Biuret method was applied for total protein and bromocresol green for albumin serum. Independent sample t-test with a significant value <0.05 was used to determine the difference between mean total protein and albumin levels. Results: The percentage of low total protein levels in malnourished children was 36%, and the percentage of low albumin levels was 27%. The mean level of total protein and albumin was found to be lower in malnourished than in well-nourished children, 6.324±1.1748 g/dL vs. 7.047±0.6330 g/dL (p = <0.001), and 3.927 g/dL±0.7779 g/dL vs. 4.242 g/dL±0.5272 (p = 0.016), respectively. Conclusion: There were significant differences in total protein and albumin serum among malnourished and well-nourished children. The results may serve as basic information for further studies or to create an intervention to reduce malnutrition.
Latest Innovations in the Treatment of Degenerative Diseases Sembiring, Lisma Natalia Br; Astuti, Aldiana; Nazaruddin, Muhammad; Muntasir, Muntasir; Hasyim, Dadang Muhammad
Journal of World Future Medicine, Health and Nursing Vol. 2 No. 1 (2024)
Publisher : Yayasan Pendidikan Islam Daarut Thufulah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/health.v2i1.718

Abstract

Recent innovations in the treatment of degenerative diseases have become a major focus of efforts to improve the quality of life of patients. With the development of technology and scientific research, there are opportunities to develop more effective and innovative treatment methods. In this study, we aim to explore recent innovations in the treatment of degenerative diseases, the purpose of which is to showcase the latest developments in the field of medicine that can provide new solutions in the management of degenerative diseases. The research method involved a literature review of recent studies in the treatment of degenerative diseases, as well as an analysis of relevant research data. The results showed some promising recent innovations, such as gene therapy, the use of stem cell technology, nanotechnology in drug delivery, and electromagnetic field approaches in medicine. These innovations offer the potential to improve treatment effectiveness and reduce the negative impact of these degenerative diseases. From the results of this study, it can be concluded that recent innovations in the treatment of degenerative diseases offer new hope in the management of these diseases. Technological developments and scientific research provide opportunities for the development of more effective and innovative treatment methods. However, despite significant progress in this field, further research is needed to evaluate the effectiveness, safety and sustainability of these innovations. This conclusion underscores the importance of collaboration between scientists, clinicians and the pharmaceutical industry to continue to drive innovation in an effort to holistically address degenerative diseases.
Unveiling the Distinctive Traits of Aedes aegypti and Aedes albopictus Mosquito Larvae: A Remarkable Entomological Exploration for dengue fever Astuti, Aldiana; Rolanda, Rolanda
ANJANI Journal (Medical Science & Healthcare Studies) Vol 3, No 2 (2023)
Publisher : Perkumpulan Dosen Muda Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37638/anjani.v3i2.976

Abstract

ABSTRAKPendahuluan: Penyakit Demam Berdarah Dengue (DBD) merupakan ancaman global yang disebabkan oleh virus yang ditularkan melalui gigitan nyamuk Aedes aegypti dan Aedes albopictus. Penelitian ini bertujuan untuk mendalami karakteristik larva kedua jenis nyamuk tersebut melalui pendekatan entomologi, dengan tujuan memahami pola perindukan dan perilaku habitatnya. Metode: Penelitian ini mengadopsi pendekatan eksploratif entomologi dengan teknik pengambilan sampel larva menggunakan metode simple random sampling. Fokus utama penelitian adalah pada identifikasi ciri khas larva Aedes aegypti dan Aedes albopictus serta distribusi perindukannya di area penelitian. Hasil: Hasil penelitian mengungkapkan ciri khas larva Aedes aegypti dan Aedes albopictus yang mencolok, dengan perbedaan dalam pola perindukan dan prevalensi di berbagai lingkungan. Larva Aedes aegypti cenderung mendominasi di ruangan, sementara larva Aedes albopictus lebih sering ditemukan di luar ruangan. Temuan ini memberikan wawasan mendalam mengenai adaptasi kedua jenis nyamuk terhadap lingkungan sekitarnya. Kesimpulan: Eksplorasi entomologi ini memberikan pemahaman yang lebih mendalam mengenai ciri khas larva Aedes aegypti dan Aedes albopictus, serta distribusi perindukannya di lingkungan sekitar. Penelitian ini memberikan dasar untuk pengembangan strategi pengendalian vektor yang lebih efektif dalam upaya pencegahan Demam Berdarah Dengue. Hasil ini diharapkan dapat menjadi landasan bagi intervensi yang tepat dan berkelanjutan untuk mengurangi risiko penularan DBD. ABSTRACTIntroduction: Dengue Hemorrhagic Fever (DHF) is a global threat caused by viruses transmitted through the bites of Aedes aegypti and Aedes albopictus mosquitoes. This research aims to delve into the characteristics of larvae of both mosquito species through an entomological approach, with the goal of understanding their breeding patterns and habitat behavior. Methodology: The study adopts an exploratory entomological approach with larval sampling using the simple random sampling method. The primary focus of the research is on identifying the distinctive features of Aedes aegypti and Aedes albopictus larvae, as well as their distribution of breeding sites within the study area. Results: The research reveals striking characteristics of Aedes aegypti and Aedes albopictus larvae, showing differences in breeding patterns and prevalence across various environments. Aedes aegypti larvae tend to dominate indoor locations, while Aedes albopictus larvae are more commonly found in outdoor settings. These findings provide profound insights into the adaptation of both mosquito species to their surrounding environments. Conclusion: This entomological exploration offers a deeper understanding of the distinctive characteristics of Aedes aegypti and Aedes albopictus larvae, along with the distribution of their breeding sites in the surrounding environment. The research provides a foundation for the development of more effective vector control strategies in the effort to prevent Dengue Hemorrhagic Fever. These results are expected to serve as a basis for appropriate and sustainable interventions to reduce the risk of Dengue transmission.
Bibliometric Analysis of the Impact of Work-Life Balance on Mental Health in the Workplace Erliana, Yossy Dwi; Arisanti, Ivon; Astuti, Aldiana; Indriawati, Ratna; Wilanda, Alifah
West Science Social and Humanities Studies Vol. 2 No. 08 (2024): West Science Social and Humanities Studies
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsshs.v2i08.1213

Abstract

This bibliometric study investigates the academic landscape surrounding work-life balance, exploring the interrelations between work-life balance and its impacts on mental health, job satisfaction, and organizational performance. Utilizing data from major academic databases from 2000 to 2023 and employing VOSviewer for network analysis, the study maps the evolution of research themes, with a special focus on changes influenced by the COVID-19 pandemic. The findings highlight the increased emphasis on mental health issues, flexibility in work arrangements, and the critical role of workplace support. The study also identifies central researchers and thematic clusters, illustrating the dynamic interplay between work-life balance strategies and employee well-being. These insights provide a valuable foundation for developing more effective policies and interventions aimed at enhancing work-life harmony.
HBsAg Status, Molecular Detection and Therapy Evaluation of Hepatitis B Patient Djuma, Agustina W.; Dewu, Sherly; Banunu, Ayorince Herlinalt Gloria; Kambuno, Norma T.; Astuti, Aldiana
JURNAL INFO KESEHATAN Vol 21 No 4 (2023): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol21.Iss4.1110

Abstract

The management of chronic hepatitis B involves various therapeutic approaches, including nucleotide analogs (NUCs) and pegylated-interferon alpha (peg-IFN), either in isolation or in combination. Reverse transcriptase enzyme is competitively inhibited by NUCs, which effectively suppresses HBV replication and lowers viral load. Concerning their cost-effectiveness, high response rates, low side effects, and oral administration, NUCs are recommended. Prolonged use, particularly of NUCs with a low genetic barrier or as monotherapy, can, however, lead to resistance, long-term safety issues, and the need for ongoing treatment. Physicians and other healthcare professionals are extremely concerned about the emergence of resistance and possible safety concerns related to the long-term use of NUCs. Moreover, the requirement for continuous therapy presents notable obstacles concerning patient adherence, distribution of healthcare resources, and overall economic viability. To clarify these problems and direct the creation of more potent and long-lasting treatment plans for chronic hepatitis B, urgent research is required. Hepatitis B surface antigen (HBsAg) detection is frequently accomplished via the use of the Chemiluminescent Microparticle Immunoassay (CMIA), which is a crucial early serologic marker for screening and diagnosis. Polymerase chain reaction (PCR) molecular testing is employed to confirm the presence of HBsAg. Polymerase Chain Reaction (PCR) was the technique we utilized to verify the outcomes. Twenty-eight of the HBsAg-positive patients at W.Z. Johannes Kupang Hospital had positive PCR results, highlighting the significance of molecular confirmation. The results of this study emphasize the value of precise HBsAg testing and the supplementary function of molecular confirmation in the treatment of patients with chronic hepatitis B. Furthermore, it clarifies the current therapeutic approaches applied to this patient population, highlighting the necessity of customized therapeutic approaches based on each patient's unique profile and potential complications.
Pengaruh Penambahan Ekstrak Kulit Terong Ungu pada Tahu yang Mengandung Formalin Rantesalu, Agnes; Rohi Bire, Winioliski L. O.; Tangkelangi, Marni; Astuti, Aldiana
Jurnal Sehat Mandiri Vol 19 No 1 (2024): Jurnal Sehat Mandiri, Volume 19, No.1 Juni 2024
Publisher : Poltekkes Kemenkes Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33761/jsm.v19i1.1421

Abstract

Testing for formalin content in food is usually done through laboratory tests using chemicals, making it difficult for people to use it. As an alternative, formalin testing can be done with natural ingredients containing anthocyanins. This study aims to determine the formalin test on purple eggplant skin. This study is an experimental study. The method used is colorimetry by extracting anthocyanins from purple eggplant and testing them on tofu given formalin. Materials such as white tofu, formalin solution, distilled water, ethanol, purple eggplant, and label paper. The tools used in this study were hot plates, dropper pipes, stirring rods, mortars, evaporators, spray bottles, bulbs, and glassware commonly used in chemistry laboratories. This study was conducted in May - December 2023 at the Kupang City Health Laboratory. The results showed an efficient natural method for identifying formalin in food is to use eggplant skin extract. The ideal anthocyanin content in eggplant skin extract can be maintained using the right extraction method. As a result, the use of eggplant skin extract as a test material for formalin can be a practical and environmentally friendly substitute. In conclusion, the use of eggplant skin extract can be a reliable and environmentally friendly solution for detecting formalin in food products. Suggestions are to test the effectiveness of this eggplant skin extract on various types of food. Thus, it can be known how far the reliability of this method in detecting formalin accurately.
Co-Authors Agnes Rantesalu Agustina Welhelmina Djuma Arisanti, Ivon Banunu, Ayorince Herlinalt Gloria Bia, Michael Bhadi Dadang Muhammad Hasyim Dewu, Sherly Djami, Supriati Wila Erliana, Yossy Dwi Kambuno, Norma T. Marni Tangkelangi Muntasir, Muntasir Natalia Lisma Br Sembiring Ratna Indriawati, Ratna Rohi Bire, Winioliski L. O. Rolanda, Rolanda Wilanda, Alifah