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Evaluation of artemisinin-based combination therapy (ACT) to uncomplicated falciparum malaria patients in Purworejo District, Central Java, Indonesia Michael Bhadi Bia; E. Elsa Herdiana Murhandarwati; Neil F Lobo; William A Hawley; . Supargiyono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 48, No 1 (2016)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Artemisinin-based Combination Therapy (ACT) to treat uncomplicated Plasmodiumfalciparum malaria has been applied in Purworejo District, Central Java, Indonesia, since2004. However evaluation of the two ACT regimens used ie: Artesunate Amodiaquine(AAQ) and Dihydroartemisinin-Piperaquine (DHP) co-administered with Primaquine (PQ)has not been performed. This study aims to evaluate the efficacy and side effects ofAAQ+PQ and DHP+PQ treatment in uncomplicated falciparum malaria in Purworejo. Inthis descriptive and observational study, 46 Pf infected patients who fullfill the inclusionand exclusion criterias were recruited from December 2010 to August 2011. StandardACT treatment were given to the patients followed by WHO drug efficacy evaluation for28 days. The clinical symptoms and adverse events was also evaluated over the course ofthe treatment. From all recruited subjects, 37 patients received DHP+PQ and 9 patientsreceived AAQ+PQ. On the DHP+PQ treated patient, all subjects were free of asexualand sexual parasites by Day-3 while on AAQ+PQ treated patient, this parasite clearancewas achieved faster as early as on D-2 at the latest. On the otherhand, the disappearanceof fever was also last longer in DHP+PQ treated patient which in one patient last onD-14, while in AAQ+PQ treated patient, the symptom of fever dissappeared by D-2at the latest. No Early or Late Treatment Failures were found on either DHP+PQ orAAQ+PQ treatment as well as clinical and parasitological failures. However, the presenceof adverse events cause by both drugs should not be ignored to ensure drug compliance.

Serum total protein and albumin levels among malnourished elementary-aged children East Nusa Tenggara, Indonesia Tangkelangi, Marni; Djami, Supriati Wila; Bia, Michael Bhadi; Astuti, Aldiana
Public Health of Indonesia Vol. 8 No. 4 (2022): October - December
Publisher : YCAB Publisher & IAKMI SULTRA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v8i4.643

Background: School-aged children between 6-12 years are a vulnerable group that could be affected by malnutrition, which may cause growth failure and affect their school achievement. East Nusa Tenggara, Indonesia, is known as the province with the highest cases of malnutrition. Objective: This study aimed to determine serum total protein and albumin levels among malnourished elementary-aged children. Serum total protein and albumin are biochemical parameters that give valuable data due to malnutrition. Methods: This study employed a case-control design. Purposive sampling was used to select the samples with a total of 90 children aged 6 – 12 years, of which 45 were assigned to a case group and a control group. The children’s blood was collected and analyzed using Riele Photometer 5010. The Biuret method was applied for total protein and bromocresol green for albumin serum. Independent sample t-test with a significant value <0.05 was used to determine the difference between mean total protein and albumin levels. Results: The percentage of low total protein levels in malnourished children was 36%, and the percentage of low albumin levels was 27%. The mean level of total protein and albumin was found to be lower in malnourished than in well-nourished children, 6.324±1.1748 g/dL vs. 7.047±0.6330 g/dL (p = <0.001), and 3.927 g/dL±0.7779 g/dL vs. 4.242 g/dL±0.5272 (p = 0.016), respectively. Conclusion: There were significant differences in total protein and albumin serum among malnourished and well-nourished children. The results may serve as basic information for further studies or to create an intervention to reduce malnutrition.

MEDIA UBI NUABOSI DAN UBI KUNING (Manihot utilissama) SEBAGAI SUBSTITUSI PADA PERTUMBUHAN BAKTERI Escherichia coli DAN Staphylococcus aureus Agnensia Samma Djala; Michael Bhadi Bia; Norma Tiku Kambuno
Journal of Indonesian Medical Laboratory and Science Vol 4 No 2: Oktober 2023
Publisher : Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53699/joimedlabs.v4i2.123

Indonesia has natural wealth with its biodiversity, UNESCO also declared Indonesia as the 2nd megabiodiversity country after Brazil. The number of natural resources that have been used as a substitute for bacterial growth media encourages researchers to study and create alternative media to replace nutrient agar derived from nuabosi cassava and yellow cassava. This study aims to determine the media of nuabosi cassava and yellow cassava can be used as an alternative to nutrient agar media for the growth of Escherichia coli and Staphylococcus aureus bacteria. This study is a true experimental study with a posttest-only control design where the effect of treatment is analyzed using a different test, namely the one way ANOVA test. The results showed the average number of colonies growth of Escherichia coli bacteria on nuabosi cassava media was 530 CFU/mL, yellow cassava media 599 CFU/mL, and nutrient agar medium as a control was 435 CFU/mL, while for Stapylococcus aureus which was grown on nutrient agar media as control as much as 708 CFU/mL, nuabosi cassava media 434 CFU/mL, and yellow cassava media 103 CFU/mL. The results of the one way ANOVA statistical test on the growth of Escherichia coli bacteria on nuabosi cassava, yellow cassava, and nutrient media in order to obtain a p value of 0.059 (p > 0.05) this indicates that there is no significant difference, which means either yellow cassava media , nuabosi cassava media and nutrient agar media had the same ability on the growth of Escherichia coli bacteria, while the one way ANOVA statistical test for the growth of Staphylococcus aureus bacteria on nuabosi cassava media, yellow cassava media, and nutrient media in order to obtain a significance value of 0.000 ( p < 0.05), it shows that there is a significant difference. Based on the results of the analysis on yellow cassava media and nuabosi cassava media, it can be used as an alternative medium to replace the growth of Escherichia coli and Staphylococcus aureus bacteria.

SCREENING KADAR C-REAKTIV PROTEIN PENDERITA HIPERTENSI PADA MASYARAKAT DESA BONE KECAMATAN NEKAMESE KABUPATEN KUPANG Adrianus Ola Wuan; Ni Ketut Yuliana Sari; Wilhelmus Olin; Michael Bhadi Bia
SWARNA: Jurnal Pengabdian Kepada Masyarakat Vol. 2 No. 12 (2023): SWARNA: Jurnal Pengabdian Kepada Masyarakat, Desember 2023
Publisher : LPPM Sekolah Tinggi Ilmu Ekonomi 45 Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/swarna.v2i12.1068

Hipertensi adalah meningkatnya tekanan darah atau kekuatan menekan darah pada dinding rongga dimana darah itu berada. Hipertensi akan membuat kerja jantung lebih berat, bila hipertensi berlangsung lama maka akan menyebabkan kerusakan yang terjadi pada jantung (melalui arteri koroner) dan menyebabkan aterosklerosis. Hipertensi akan mengakibatkan hilangnya elastisitas arteri, meningkatnya aktivitas dan tegangan akhirnya akan melemahkan dinding arteri dan melukai permukaanya. Luka dan peradangan kecil mulai terbentuk, kemudian akan menarik kolesterol berbahaya dalam jumlah besar, serta bahan-bahan lain yang bersifat mengiritasi, lalu seiring berjalannya waktu akan semakin menumpuk sehingga menyebabkan arteri menjadi tidak elastis lagi. Setelah dibiarkan bertahun-tahun maka tekanan darah tinggi yang terus menerus ini akan menyebabkan aterosklerosis. Terjadinya aterosklerosis dapat menyebabkan timbulnya inflamasi yang ditandai dengan meningkatnya kadar C-Reactive Protein (CRP) dalam darah. CRP merupakan salah satu protein fase akut yang meningkat selama inflamasi sistemik. Tujuan dari kegiatan ini untuk mengetahui gambaran C-Reaktif Protein penderita Hipertensi pada Masyarakat di Desa Bone Kecamatan Nekamese Kabupaten Kupang. Pelaksanaan kegiatan Pengabdian Masyarakat dilaksanakan di Desa Bone Kecamatan Nekamese dengan sasarannya adalah masyarakat Lansia yang menderita Hipertensi yang kemudian diperiksa kadar Creaktif proteinnya. Semua Lansia yang Hipertensi dilakukan pemeriksaan kadar C- Reaktif Proteinnya untuk menilai ada tidaknya terjadi inflamasi.Dari hasil pelaksanaan kegiatan disimpulkan bahwa semua Lansia hipertensi memiliki kadar C-Reaktif Protein yang normal. Hal ini disebabkan karena adanya kegiatan pemeriksaan Kesehatan rutin yang dilakukan oleh Puskesmas setempat sehingga status hipertensinya dapat dikontrol dengan baik.

Screening Kadar Rheumatoid Factor (RF) Pada Lanjut Usia (Lansia) Dengan Keluhan Nyeri Sendi Adrianus Ola Wuan; Marni Tangkelangi; Wilhelmus Olin; Michael Bhadi Bia; Ni Ketut Yuliana Sari
Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia Vol. 2 No. 2 (2023): Juni : Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia
Publisher : Sekolah Tinggi Ilmu Administrasi Yappi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jppmi.v2i2.457

Rheumatoid arthritis is an autoimmune disease that occurs when the body's immune system mistakenly attacks healthy joints. The disease can start at any age, but the likelihood of onset is highest in older adults. In Rheumatoid Arthritis the tissue lining the joints becomes thickened resulting in swelling and pain. Elderly is an age that has a greater possibility of having an autoimmune this is based on the statement that the older you are, the greater the chance of having an autoimmune. Early diagnosis and treatment isthe key to successful treatment of Rheumatoid Arthritis because joint damage cannot be restored once it occurs. Rhematoid Factor examination is largely used to help diagnose rheumatoid arthritis. Community service activities aim to determine the description of RF levels in the elderly with supply disorders, descriptive research type with a cross sectional approach. The sampling technique used purposive sampling as many as 62 elderly people in the Social Service of NTT Province. The results of RF examination in all elderly samples 6.45% have positive results and 93.55% negative results.

Personal Hygiene and Soil Transmitted Helminth Incidence in Elementary School Students Amanuban Barat District, South Central Timor Bia, Michael Bhadi; Susilawati, Ni Made; Rantesalu, Agnes; Octrisdey, Karol; Bire, Winioliski L.O. Rohi
JURNAL INFO KESEHATAN Vol 20 No 2 (2022): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol20.Iss2.932

Soil-transmitted helminth infection remained a significant public health problem in many developing countries. Elementary school-age children dominated the cases in Indonesia due to poor personal hygiene. South Central Timor had the top three poverty and the highest stunting rates in East Nusa Tenggara. Research to examine the relationship between personal hygiene and the incidence of Soil-Transmitted Helminth infection had never been conducted in South Central Timor. The study population consisted of 279 elementary school students selected from Inpres Nulle Elementary School, Inpres Neonmat Elementary School, and GMIT Nulle Elementary School through the Multistage Random Sampling technique. It was obtained 160 children as the study samples. The study found that 46 children (29.0%) were positive for STH, and 114 (71.0%) were negative for STH. Furthermore, 30 (65.2%) were positive for hookworm, 14 (30.4%) were positive for Ascaris lumbricoides, and 2 (4.4%) children had mixed infections. Multiple Logistic Regression Tests showed a significant effect of washing hands with soap after defecating with p = 0.031 and OR = 7.158. Thus, if a child did not wash his hands with soap after defecating, he had a risk of STH infection by 7.158 times. Furthermore, the effect of eating habits obtained a p = 0.038 and an OR value = 0.133 with the possibility of eating habits that did not protect against STH infection. In addition, the effect of dirty nails obtained a p=0.064 and an OR=5.264, which indicated the risk of contracting STH by 5.264 times. The effect of snacking habit obtained a p = 0.005 and an OR=0.121. It can be concluded that the incidence of STH was simultaneously influenced by the habit of defecating on the ground, washing hands without soap after defecation, eating raw food, having dirty nails, and having poor snacking habits.

SCREENING KADAR C-REAKTIV PROTEIN PENDERITA HIPERTENSI PADA MASYARAKAT DESA BONE KECAMATAN NEKAMESE KABUPATEN KUPANG Wuan, Adrianus Ola; Sari, Ni Ketut Yuliana; Olin, Wilhelmus; Bia, Michael Bhadi
SWARNA: Jurnal Pengabdian Kepada Masyarakat Vol. 2 No. 12 (2023): SWARNA: Jurnal Pengabdian Kepada Masyarakat, Desember 2023
Publisher : LPPM Sekolah Tinggi Ilmu Ekonomi 45 Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/swarna.v2i12.1068

Hipertensi adalah meningkatnya tekanan darah atau kekuatan menekan darah pada dinding rongga dimana darah itu berada. Hipertensi akan membuat kerja jantung lebih berat, bila hipertensi berlangsung lama maka akan menyebabkan kerusakan yang terjadi pada jantung (melalui arteri koroner) dan menyebabkan aterosklerosis. Hipertensi akan mengakibatkan hilangnya elastisitas arteri, meningkatnya aktivitas dan tegangan akhirnya akan melemahkan dinding arteri dan melukai permukaanya. Luka dan peradangan kecil mulai terbentuk, kemudian akan menarik kolesterol berbahaya dalam jumlah besar, serta bahan-bahan lain yang bersifat mengiritasi, lalu seiring berjalannya waktu akan semakin menumpuk sehingga menyebabkan arteri menjadi tidak elastis lagi. Setelah dibiarkan bertahun-tahun maka tekanan darah tinggi yang terus menerus ini akan menyebabkan aterosklerosis. Terjadinya aterosklerosis dapat menyebabkan timbulnya inflamasi yang ditandai dengan meningkatnya kadar C-Reactive Protein (CRP) dalam darah. CRP merupakan salah satu protein fase akut yang meningkat selama inflamasi sistemik. Tujuan dari kegiatan ini untuk mengetahui gambaran C-Reaktif Protein penderita Hipertensi pada Masyarakat di Desa Bone Kecamatan Nekamese Kabupaten Kupang. Pelaksanaan kegiatan Pengabdian Masyarakat dilaksanakan di Desa Bone Kecamatan Nekamese dengan sasarannya adalah masyarakat Lansia yang menderita Hipertensi yang kemudian diperiksa kadar Creaktif proteinnya. Semua Lansia yang Hipertensi dilakukan pemeriksaan kadar C- Reaktif Proteinnya untuk menilai ada tidaknya terjadi inflamasi.Dari hasil pelaksanaan kegiatan disimpulkan bahwa semua Lansia hipertensi memiliki kadar C-Reaktif Protein yang normal. Hal ini disebabkan karena adanya kegiatan pemeriksaan Kesehatan rutin yang dilakukan oleh Puskesmas setempat sehingga status hipertensinya dapat dikontrol dengan baik.

Pediculosis capitis in Elementary School Children in Kupang Regency Michael Bhadi Bia; Aldiana Astuti; Lidia Vartika Putri; Noldiana Rini Hello; Junita Mogu Wole
Laboratory Journal of Infectious Diseases Vol. 1 No. 1 (2025): Laboratory Journal of Infectious Diseases
Publisher : Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/ljid.v1i1.2157

Pediculosis capitis is a parasitic infestation caused by the head louse, Pediculus humanus capitis (PHC). These lice feed on human blood on the head. Head lice infestations most commonly occur among preschool and primary school children, as well as household members and caregivers. This study was conducted to provide an overview of the evidence regarding the prevalence of pediculosis capitis among primary school students in Kupang Regency, East Nusa Tenggara. This study aimed to determine the prevalence of pediculosis capitis and identify risk factors influencing its occurrence among primary school students in Kupang Regency. The study was conducted in primary schools in Kupang Regency during the 2023–2024 academic year. To identify cases of pediculosis, the presence of eggs/nymphs/adult PHC was detected using a lice comb. Clinical symptoms and signs were collected through interviews using a questionnaire and direct observation of clinical signs. A total of 278 children participated in the study, consisting of 164 boys (59%) and 114 girls (41%). Pediculosis cases were found in 151 children (54,3%). Characteristics of children influencing the occurrence of pediculosis include hair length and the number of family members living in the same household. Reported symptoms associated with pediculosis cases included dandruff, scalp itching, redness, difficulty sleeping, and poor concentration. Behaviours of primary school children related to the transmission of pediculosis include sleeping with an infected person, sharing hats, sharing combs at home, frequency of using a lice comb, and frequency of washing hair per week.

Correlation of Anemia Status in Mothers and Stunted Toddlers Florida Ester Pailau; Michael Bhadi Bia; Supriati Wila Djami; Ni Ketut Yuliana Sari; Atun Farihatun
Laboratory Journal of Infectious Diseases Vol. 1 No. 2 (2025): Laboratory Journal of Infectious Diseases
Publisher : Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Postpartum anemia remains a public health concern due to its potential impact on maternal and child health. This study aimed to analyze the correlation between maternal anemia status and anemia among stunted toddlers. An analytical observational study with a cross-sectional design was conducted at Pustu Noelbaki. The study subjects were mothers and their stunted toddlers selected using purposive sampling. A total of 40 participants were included, consisting of 20 mothers and 20 stunted toddlers. Maternal and toddler anemia status were assessed and analyzed using statistical correlation testing with a significance level of p < 0,05. The results showed that 25% of mothers were anemic, while 55% of stunted toddlers had anemia. Statistical analysis demonstrated a p-value of 0,319 (p > 0,05), indicating no significant correlation between maternal anemia status and anemia among stunted toddlers. In conclusion, maternal anemia was not significantly associated with anemia in stunted toddlers in this study. Further research with larger sample sizes is recommended to better understand potential contributing factors.

Peningkatan Peran Guru Sekolah Dasar dalam Pencegahan Infeksi Parasite di Desa Bone : Enhancing The Role of Primary School Teachers in Preventing Parasite Infections in Bone Village Michael Bhadi Bia; Adrianus Ola Wuan; Novian Agni Yudhaswara
Jurnal Pengabdian Kepada Masyarakat: Kesehatan Vol. 6 No. 1 (2026): Maret
Publisher : Sekolah Tinggi Ilmu Kesehatan Notokusumo Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstrak: Penyakit infeksi seperti kecacingan, demam berdarah dengue (DBD), dan kutu kepala masih menjadi masalah kesehatan pada anak usia sekolah dasar. Guru memiliki peran penting sebagai agen edukasi dalam upaya pencegahan penyakit tersebut di lingkungan sekolah. Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan guru SDN Bone Kecamatan Nekamese terkait pencegahan kecacingan, DBD, dan kutu kepala. Kegiatan dilaksanakan melalui dua tahapan, yaitu ceramah dan praktikum. Evaluasi dilakukan menggunakan desain pretest dan posttest sebelum dan sesudah pemberian materi, baik teori maupun praktik, dengan menggunakan aplikasi Google Form. Peserta kegiatan berjumlah delapan orang guru. Hasil pretest menunjukkan bahwa pengetahuan awal guru masih bervariasi, terutama pada materi DBD, langkah cuci tangan yang benar, serta pencegahan kutu kepala. Setelah dilakukan intervensi, hasil posttest menunjukkan peningkatan pengetahuan yang signifikan, di mana seluruh peserta (100%) mampu menjawab dengan benar seluruh pertanyaan yang diberikan. Kegiatan ini menunjukkan bahwa edukasi kesehatan melalui metode ceramah dan praktikum efektif dalam meningkatkan pengetahuan guru mengenai pencegahan penyakit infeksi pada anak usia sekolah. Diharapkan peningkatan pengetahuan ini dapat diterapkan dan disebarluaskan kepada siswa serta orang tua guna mendukung upaya promotif dan preventif kesehatan di sekolah. Abstract: Infectious diseases such as helminthiasis, dengue hemorrhagic fever (DHF), and head lice infestation remain public health problems among elementary school–aged children. Teachers play an important role as health education agents in preventing these diseases within the school environment. This community service activity aimed to improve the knowledge of teachers at SDN Bone, Nekamese District, regarding the prevention of helminthiasis, DHF, and head lice infestation. The activity was conducted in two stages, namely lectures and practical sessions. Evaluation was carried out using a pre-test and post-test design before and after the delivery of theoretical and practical materials through Google Forms. The participants consisted of eight teachers. The pre-test results indicated varying levels of baseline knowledge, particularly regarding dengue prevention, proper handwashing steps, and head lice prevention. After the intervention, the post-test results showed a significant improvement in knowledge, with all participants (100%) correctly answering all questions. This activity demonstrates that health education using lecture and practical methods is effective in improving teachers’ knowledge of infectious disease prevention among school-aged children. It is expected that the improved knowledge will be applied and disseminated to students and parents to support promotive and preventive health efforts in schools.

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