Claim Missing Document
Check
Articles

Found 12 Documents
Search

Association Between Maternal Factors and Stunting Based on the Indonesia Family Life Survey 5 (IFLS-5) Sukamto, Charissa Otniel; Fatimah, Siti Nur; Indraswari, Noormarina
Makara Journal of Health Research Vol. 30, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Stunting remains a major issue in Indonesia. Maternal factors during pregnancy are one of the key determinants in preventing stunting. This study aimed to analyze the association between maternal history during pregnancy (age, height, parity, and inter-pregnancy interval) and stunting, with a comparison between urban and rural areas. Methods: This analytical cross-sectional study used data from 3,639 children aged 1-5 years old from the household survey of Indonesia Family Life Survey 5, conducted between late October 2014 and August 2015 within 13 provinces in Indonesia. Data was analyzed using chi-square and binary logistic regression methods. Results: The toddlers were predominantly boys (51.9%), with a mean age of 3 years (1–5). Around 37% were stunted. Stunting was associated with adolescent mothers, short maternal stature, high parity, and rural residence. In both urban and rural areas, these maternal factors were significantly associated with stunting. Conclusions: Younger maternal age, lower maternal height, and high parity were significant predictors of stunting, including in both urban and rural areas. Stunting management strategies should prioritize reducing early pregnancy, improving maternal nutrition, and limiting high parity with equitable implementation across rural areas to address existing disparities in Indonesia.
Nutriepigenetic Modulation of Hypertension Risk: A Review of the Literature Maria Riastuti Iryaningrum; Nanny Natalia Mulyani Soetedjo; Noormarina Indraswari; Rudi Supriyadi
Indonesian Journal of Global Health Research Vol 7 No 2 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i2.4774

Abstract

This review aimed to investigate the interplay between dietary components and epigenetic modulation in the pathogenesis of hypertension. A comprehensive literature search encompassing all published primary and secondary research dating up to March 2024 was carried out on several electronic databases, including MEDLINE, EBSCO-Host, Science Direct, ProQuest, and Google Scholar. Individual genomes and dietary intake exhibit a bidirectional relationship, influencing the hypertension risk. Unhealthy dietary patterns can compromise DNA integrity through DNA methylation and histone acetylation, ultimately affecting both systolic and diastolic blood pressure. Dietary macronutrient composition (carbohydrates, lipids, and proteins) significantly alters the expression of specific microRNAs (miRNAs) known to regulate endothelial function and blood pressure homeostasis. Moreover, micronutrients (vitamin A, D, E, Zinc, Iodine, and Sodium) can exert epigenetic effects on blood pressure via receptor interactions, potentially modifying cardiovascular disease risk. Dietary imbalances in macro and micronutrients can epigenetically influence hypertension development. Addressing these deficiencies through targeted interventions may offer a complementary approach to hypertension treatment.