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All Journal Buletin Farmatera Jurnal Respirologi Indonesia The Journal of Society Medicine (JSOCMED)
Sinaga, Bintang YM
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

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Factors that Influencing Sputum Conversion at the End of Intensive Phase on TB-DM Patients at Medical Health Service in Medan Pertiwi, Vani Gita; Sinaga, Bintang YM; Lindarto, Dharma
Buletin Farmatera Vol 6, No 2 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i2.4767

Abstract

Tuberculosis and type 2 DM are the main problems of health in the world, including Indonesia. Many sputum conversion failures are found in TB-DM patients. This study aims to know about the factors that influence sputum conversion at the end of the intensive phase on TB-DM patients at the Medical Health Service in Medan. This research was carried out in a Specialized Lung Hospital and eight Health Centers in Medan. The Design of this study is observational analytic with a Cross-Sectional approach that took place in October-December 2019. Of 76 patients, there were 65 subjects (85.5%) with sputum conversion and 11 subjects (14.5%) without sputum conversion, the number of male patients was 48 subjects (63.2%), elderly were 51 subjects (67.1%), the normals BMI were 54 subjects (71.0%), patients with smoking were 4 subjects (5.3%), previous alcohol consumptions were 6 subjects (7.9%), current blood sugar levels 200 mg/dl are 23 subjects (30.2%) and the patients which using the anti-diabetes medication regularly were 62 subjects (81.6%). This study found that there was a significant relationship between alcohol, current blood sugar levels, and regularity using anti-diabetes medication with sputum conversion (p=0.036, p=0.001, p=0.001), while the factors that influence sputum conversion are alcohol and regularity using anti-diabetes medication (p=0.032, dan p=0.001).
Characteristics of Loss to Follow-Up Patient in Drug-Sensitive Pulmonary TB in Medan Sari Mardia, Rina; Sinaga, Bintang YM; Siagian, Parluhutan; Taufik, Ashar
Journal of Society Medicine Vol. 3 No. 10 (2024): Oktober
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i10.166

Abstract

Introduction: Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis. Adherence to TB treatment is a complex and dynamic phenomenon with various interacting factors. The characteristics of loss to follow-up patients include social, clinical, and economic characteristics. The Aim of study was to identify characteristics of loss to follow-up patients in drug-sensitive pulmonary TB in Medan. Method: This research is a descriptive study using a cross-sectional approach. All variables were measured and observed at a time during the study. The study was conducted at RSUP Adam Malik Medan and Prof. Dr. Chairuddin P. Lubis USU Hospital in loss to follow-up TB patients diagnosed bacteriologically that meet the criteria of inclusion and exclusion. This study used data from medical records and questionnaires. Independent variables include age, gender, educational level, employment, marital status, family history of lung tuberculosis, attitudes to TB treatment, social support, health services, and reasons for loss to follow-up. Results: Out of 40 patients with loss to follow-up pulmonary tuberculosis, the majority were patients in the age range of 45-65 years (n=26.65%), male (n=31.77,5%), equal level of high school education (n = 24.60%) had a fixed job (n=33.82.5%), marital status (n=33.90%), had no family history of lung tuberculosis (n=36.90%), poor attitude to TB treatment (n=36.90%), received low social support (n=51.52,5%), and received less supported health care services (n<33.82,5%). Reasons patients TB SO quit taking medication presented in this study vary, among others due to the side effects of TB drugs, patients choosing herbal drugs, already feeling healthy, laziness consuming TB medication, being embarrassed with pulmonary TB disease, not taking lung TB drugs because no one carries or has no transportation costs. Conclusion: The majority of patients with drug-sensitive pulmonary tuberculosis who quit their medication in the fields are between 46 and 65 years of age, male sex, high school graduates of equal degree, have a fixed job, marital status, have no family history of TB, have an inferior attitude to TB treatment, receive low social support, and receive less supportive health services. Reasons for loss to follow-up for SO TB patients vary, including TB drug effects, clinical, and economic.
The Overview Side Effects of MDR TB Short Term Regimen for Heart and Kidney Function in MDR TB Patients at H. Adam Malik General Hospital Medan, North Sumatra Santy, Diana; Siagian, Parluhutan; Sinaga, Bintang YM; Eyanoer, Putri C
Jurnal Respirologi Indonesia Vol 44 No 1 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i1.573

Abstract

Background: World Health Organization issued a recommendation for the use of standard 9–11 month Shorter Multidrug-Drug Resistant Tuberculosis (MDR TB) regimen. It will impact the number of patients treated and improve obedience because of the shorter, low cost, and well-tolerated. However, MDR TB drugs allow side effects both mild, moderate and severe. If severe side effects occur, the patient will stop treatment and close monitoring required. An optimal and adequate care of side effects is the key of the successful of MDR TB treatment. The aim of this study was to determine the side effects that occured in the treatment of MDR TB patients with short term regimen (STR) on heart and kidney function at H. Adam Malik General Hospital Medan, North Sumatra.Methods: A case series design with a total of 76 MDR TB patients who underwent a shorter regimen. Samples were obtained from the medical record in the pulmonary isolation inward and MDR TB polyclinic at Adam Malik Hospital, Indonesia. Data were analyzed descriptively to identify changes in heart (Prolong QTc) and kidney function of the nine months treatment.Results: 76 data were collected, the number of male samples was 68.4% and 31.6% were women with the age group of the study subjects being mostly followed by 41-50 years of age. There was a significant increase in value occurred in 4-6 months of treatment related to the side effects of treatment on heart (Prolong QTc) and kidney function.Conclusion: There was a trend to increase the value of heart (Prolong QTc) and kidney function significantly occurred 4-6 months after the patient underwent MDR TB treatment with STR.
Co-Authors dharma Lindarto, dharma Eyanoer, Putri C Parluhutan Siagian Pertiwi, Vani Gita Santy, Diana Sari Mardia, Rina Taufik, Ashar