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All Journal Buletin Farmatera JURNAL PENDIDIKAN TAMBUSAI SRIWIJAYA JOURNAL OF MEDICINE JURNAL ILMIAH SIMANTEK Prominentia Medical Journal
Irma, Fani Ade
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Journal : Buletin Farmatera

 1 
Blood Transfusion Therapy in Patients with Autoimmune Hemolytic Anemia Irma, Fani Ade
Buletin Farmatera Vol 7, No 1 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v7i1.9478

Abstract

Management therapy of autoimmune hemolytic anemia (AIHA) with severe clinical symptoms requires supportive therapy such as blood components transfusion to improve hemodynamic conditions. This literature study aims to explain the role of blood transfusion therapy in AIHA cases. The method used is through searching articles in national and international journals published in the last 10 years that discuss transfusion in AIHA cases using the Google Scholar application. From the search results, it can be concluded that blood transfusion is a supportive therapy in cases of AIHA with symptoms of severe hypoxemia that interfere with hemodynamics and work function of body organ systems and findings of Hb levels 7 mg/dL with the selection of blood components in the form of packed red cells (PRC), washed packed red cells (WPRC) and Leucoreduction (LR).
Total Leukocyte Count And Platelet Count Are Related To TUBEX-TF Positivity Results In Typhoid Fever Patients At Dr. Pirngadi Hospital Medan City In 2018-2021 Utami, Mega Diahsyah; Irma, Fani Ade
Buletin Farmatera Vol 10, No 1 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i1.24436

Abstract

Abstract: Typhoid fever is a gastrointestinal infection caused by Sallmonellal typhi and Sallmonella serovar Paratyphi A (an important inhibitor of typhoid fever). Typhoid fever can be diagnosed based on clinical signs and symptoms, and laboratory tests. Leukopenia occurs due to the invasion of the bacterium Salmonella typhi into hematopoietic organs such as lymph nodes, tonsils, spleen, and bone marrow, thereby inhibiting hematopoiesis.The decrease in platelet production in the bone marrow is caused by viral infections, the destruction of platelet precursor cells in the bone marrow, radiation, aplastic bone marrow, bone marrow disorders or cancers, and other conditions that inhibit cell production in the bone marrow.This study aims to determine the relationship between total leukocyte count and platelet count in relation to Tubex-TF positivity in typhoid patients at RSUD dr. Pirngadi Medan from 2018 to 2021.This research uses an analytical observational method with a cross-sectional approach.The research sample consisted of typhoid patients at RSUD Dr. Pirngadi Medan from 2018-2021, which met the inclusion and exclusion criteria, totaling 71 patients.Analysis of the data was conducted using the chi-square test for both univariate and bivariate analyses.The total leukocyte count was found to be elevated in the case of a positive Tubex-TF in a patient with typhoid fever.
PERBANDINGAN KADAR HIGH DENSITY LIPOPROTEIN DARAH PADA PEROKOK AKTIF, PEROKOK PASIF, DAN NONPEROKOK Fadillah Pasya, Ryan; Irma, Fani Ade
Buletin Farmatera Vol 11, No 2 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i2.26702

Abstract

Abstract: Tobacco is one of the factors known to increase the risk of disease and premature death globally. Nicotine is one of the harmful substances in cigarettes that can result in the release of hormones such as catecholamines, cortisol, and growth hormone. The release of these hormones can alter the lipid profile in the blood, including increased total cholesterol levels, Very Low-Density Lipoprotein (VLDL), Low Density Lipoprotein (LDL), and decreased High Density Lipoprotein (HDL) levels. This study aims to determine the comparison of HDL levels in active smokers, passive smokers, and non-smokers.  The total sample in this study was 45 people who were divided equally into three different groups, namely active smokers, passive smokers, and non-smokers. Data analysis was processed using SPSS. Research shows there is a difference in HDL levels between active smokers, passive smokers, and nonsmokers (p0.05). Smoking can significantly lower HDL levels in the blood.
Co-Authors Barus, Putri Ricka Amelia Fadillah Pasya, Ryan fathanaya, Harris Ginting, Dhio Emerko SIREGAR, SITI MASLIANA Siti Hajar Sri Rezeki Arbaningsih UTAMI, MEGA DIAHSYAH Yulfi, Hemma