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Pengaruh merokok terhadap hasil clotting time dan bleeding time pada populasi laki-laki Fakultas Kedokteran UMSU Ginting, Dhio Emerko; Irma, Fani Ade; Arbaningsih, Sri Rezeki; Hajar, Siti
Sriwijaya Journal of Medicine Vol. 2 No. 1 (2019): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

WHO telah menetapkan Indonesia sebagai negara dengan jumlah perokok terbesar ketiga. Ada tiga zat kimia yang paling sangat berbahaya, yaitu tar, nikotin, karbon monoksida yang terkandung dalam rokok. Hasil penelitian di Inggris menunjukkan kepada kita bahwa kurang lebih 50% perokok yang merokok sejak remaja mengalami kematian akibat penyakit yang berhubungan dengan kebiasaan merokok mereka. Penelitian ini bertujuan untuk mengetahui tentang pengaruh asap rokok dengan proses kaskade clotting time. Jenis penelitian ini adalah penelitian analitik dengan menggunakan desain cross-sectional. Penelitian ini menggunakan sampel populasi laki-laki di Fakultas Kedokteran di UMSU yang diwawancara untuk mengetahui bahwa mereka merokok atau tidak, setelah itu, sampel diperiksa clotting time dan bleeding time. Data yang terkumpul dianalisis dengan uji chi-square. Hasil penelitian menunjukkan p = 0,000 bahwa ada hubungan merokok dengan clotting time dan bleeding time pada perokok berat dan sedang. Pada perokok berat dan moderat terdapat hubungan bermakna antara penurunan bleeding time dan peningkatan clotting time dengan merokok. Tidak ada hubungan antara clotting time dan merokok pada perokok ringan.
HUBUNGAN JUMLAH LEUKOSIT TOTAL DAN JUMLAH TROMBOSIT TERHADAP HASIL KEPOSITIFAN TUBEX-TF PADA PASIEN DEMAM TIFOID DI RSUD Dr. PIRNGAlDI KOTAl MEDAN TAHUN 2018-2021 UTAMI, MEGA DIAHSYAH; IRMA, FANI ADE
JURNAL ILMIAH SIMANTEK Vol 7 No 4 (2023): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Typhoid fever is an infection of the digestive tract caused by Salmonella typhi and Salmonella serovalr Palraltyphi (important causes of typhoid fever). Typhoid fever can be diagnosed based on clinical signs, symptoms, and laboratory tests. Leukopenia occurs due to the invasion of Sallmonellal Typhi Balcterial into halemopoetic organelles such as lymph nodes, tonsils, and the spleen of the spinal cord, thereby depressing the rate of hemopoiesis. Decreasing production of plaltelets in the bone malrrow can be caused by viral infections, malturaltion of plaltelet precursor cells in the bone malrrow, raldialtion, bone malrrow alplalsia, malignancy or cancer in the bone malrrow, and drugs that suppress blood cell production in the bone malrrow. This study used an observational alnallytic research method with a cross-sectional design. Daltal collection uses secondary daltal from medical records. The research sample of typhoid fever patients at RSUD Dr. Pirngaldi Medaln City in 2018–2021, which met the inclusion and exclusion criteria, was obtained with a total sample of 71 patients. Daltal alnallysis was performed univalrially and bivalrially using the chi squalre test. The result of this research is that there were 37 patients with Tubex-TF +4, 26 patients with Tubex-TF +6, and 8 patients with Tubex-TF +8. Leukocytes were detected in 9 patients, normal leukocytes in 58 patients, and abnormal leukocytes in 4 patients. Plaltelets were detected in 12 patients, normal plaltelets in 51 patients, and abnormal plaltelets in 8 patients. The conclusion is that there is a relationship between total leukocyte count and tubex-TF positive results in patients with typhoid fever. There is a relationship between plaque count and tubex-TF positive results in typhoid fever patients.
Blood Transfusion Therapy in Patients with Autoimmune Hemolytic Anemia Irma, Fani Ade
Buletin Farmatera Vol 7, No 1 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v7i1.9478

Abstract

Management therapy of autoimmune hemolytic anemia (AIHA) with severe clinical symptoms requires supportive therapy such as blood components transfusion to improve hemodynamic conditions. This literature study aims to explain the role of blood transfusion therapy in AIHA cases. The method used is through searching articles in national and international journals published in the last 10 years that discuss transfusion in AIHA cases using the Google Scholar application. From the search results, it can be concluded that blood transfusion is a supportive therapy in cases of AIHA with symptoms of severe hypoxemia that interfere with hemodynamics and work function of body organ systems and findings of Hb levels 7 mg/dL with the selection of blood components in the form of packed red cells (PRC), washed packed red cells (WPRC) and Leucoreduction (LR).
EFEKTIVITAS JIGSAW METHOD PADA PEMBELAJARAN DARING MELALUI FORUM DISKUSI ZOOM DI FAKULTAS KEDOKTERAN UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA fathanaya, Harris; Siregar, Siti Masliana; Yulfi, Hemma; Irma, Fani Ade
Bahasa Indonesia Vol 5 No 1 (2024): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v5i1.4376

Abstract

ABSTRACT During the Coronavirus Disease-2019 (COVID-19) pandemic, the education sector must adapt by switching from face-to-face teaching and learning activities to online. There are various kinds of learning methods used, Many options are switching from teacher-based learning methods to student-based learning, one of them is the jigsaw method. The jigsaw method is considered to be able to trigger cooperative nature towards others and can increase understanding of the lecture materials or issues raised. To find out how the jigsaw method affects online learning through the Zoom discussion forum. This research is an experimental study with pre-test and post-test control group design in physiology class at Faculty of Medicine, University of Muhammadiyah North Sumatra. Data analysis was conducted using SPSS with Mann Whitney test. Which will be used to determine the effectiveness of the jigsaw method in online learning through zoom application. Subjects were 180 students with 90 students in Class A (conventional method) and 90 students in Class B (jigsaw method). There was a greater increase in the mean value of pre-test (56.22) and post-test (79.44) in the jigsaw method class, compared to the mean value of pre-test (30.22) and post-test (54.67) in the conventional class. In this study, the results of the pre-test and post-test on the jigsaw class method were considered more effective than the control class on the Mann-Whitney test with p<0.001. The jigsaw method is proven to be more effective when applied to online learning than conventional learning methods.
Total Leukocyte Count And Platelet Count Are Related To TUBEX-TF Positivity Results In Typhoid Fever Patients At Dr. Pirngadi Hospital Medan City In 2018-2021 Utami, Mega Diahsyah; Irma, Fani Ade
Buletin Farmatera Vol 10, No 1 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i1.24436

Abstract

Abstract: Typhoid fever is a gastrointestinal infection caused by Sallmonellal typhi and Sallmonella serovar Paratyphi A (an important inhibitor of typhoid fever). Typhoid fever can be diagnosed based on clinical signs and symptoms, and laboratory tests. Leukopenia occurs due to the invasion of the bacterium Salmonella typhi into hematopoietic organs such as lymph nodes, tonsils, spleen, and bone marrow, thereby inhibiting hematopoiesis.The decrease in platelet production in the bone marrow is caused by viral infections, the destruction of platelet precursor cells in the bone marrow, radiation, aplastic bone marrow, bone marrow disorders or cancers, and other conditions that inhibit cell production in the bone marrow.This study aims to determine the relationship between total leukocyte count and platelet count in relation to Tubex-TF positivity in typhoid patients at RSUD dr. Pirngadi Medan from 2018 to 2021.This research uses an analytical observational method with a cross-sectional approach.The research sample consisted of typhoid patients at RSUD Dr. Pirngadi Medan from 2018-2021, which met the inclusion and exclusion criteria, totaling 71 patients.Analysis of the data was conducted using the chi-square test for both univariate and bivariate analyses.The total leukocyte count was found to be elevated in the case of a positive Tubex-TF in a patient with typhoid fever.
Perbandingan Jumlah Total Leukosit Pada Perokok Konvensional dan Perokok Elektrik Pada Mahasiswa Fakultas Kedokteran Universitas Muhammadiyah Sumatera Utara Barus, Putri Ricka Amelia; Irma, Fani Ade
Jurnal Pendidikan Tambusai Vol. 9 No. 3 (2025): Desember
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

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Abstract

Merokok sudah menjadi kebiasaan sehari-hari bagi masyarakat di Indonesia. Prevalensi merokok setiap hari di Kota Medan sebesar 55,2% angka ini lebih tinggi dibandingkan angka nasional yaitu 54% pada tahun 2016. Bahaya yang terkandung pada rokok tembakau tidak membuat pengguna rokok jera dan berhenti mengonsumsi rokok tembakau. Berbagai upaya yang dilakukan untuk mengurangi rokok tembakau. Salah satu upaya nya adalah dengan mengganti rokok tembakau dengan rokok elektrik atau e-cigarette. pada nyatanya rokok elektrik juga memiliki efek negatif bagi tubuh manusia salah satunya pada jumlah leukosit. Penelitian ini bertujuan untuk mengetahui mengetahui perbandingan jumlah total leukosit pada pengguna rokok konvensional dan rokok elektrik. Jenis penelitian ini adalah analitik observasional dengan desain cross sectional, menggunakan tehnik purposive sampling berjumlah 60 responden yang memenuhi kriteria inklusi dan eksklusi. Hasil penelitian ini telah di analisis menggunakan uji Mann-Whitney. Hasil penelitian ini menunjukan frekuensi lamanya merokok paling banyak pada responden 1-5 tahun, banyaknya merokok pada pengguna rokok konvensional 1-5 batang perhari, pada pengguna rokok elektrik 1-2 ml liquid perhari. Berdasarkan hasil uji Mann-whitney, diperoleh nilai sig. sebesar 0.525, nilai tersebut > 0.05 yang artinya tidak terdapat perbedaan jumlah total leukosit antara pengguna rokok konvensional dengan rokok elektrik. tidak terdapat perbedaan jumlah total leukosit antara pengguna rokok konvensional dengan rokok elektrik pada mahasiswa Fakultas Kedokteran Universitas Muhammadiyah Sumatera Utara.
PERBANDINGAN KADAR HIGH DENSITY LIPOPROTEIN DARAH PADA PEROKOK AKTIF, PEROKOK PASIF, DAN NONPEROKOK Fadillah Pasya, Ryan; Irma, Fani Ade
Buletin Farmatera Vol 11, No 2 (2026): (In Progress)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i2.26702

Abstract

Abstract: Tobacco is one of the factors known to increase the risk of disease and premature death globally. Nicotine is one of the harmful substances in cigarettes that can result in the release of hormones such as catecholamines, cortisol, and growth hormone. The release of these hormones can alter the lipid profile in the blood, including increased total cholesterol levels, Very Low-Density Lipoprotein (VLDL), Low Density Lipoprotein (LDL), and decreased High Density Lipoprotein (HDL) levels. This study aims to determine the comparison of HDL levels in active smokers, passive smokers, and non-smokers.  The total sample in this study was 45 people who were divided equally into three different groups, namely active smokers, passive smokers, and non-smokers. Data analysis was processed using SPSS. Research shows there is a difference in HDL levels between active smokers, passive smokers, and nonsmokers (p0.05). Smoking can significantly lower HDL levels in the blood.