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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Jurnal Surya Medika Global Health Management Journal EJOIN : Jurnal Pengabdian Masyarakat
Natalina, Riny
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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The Effect of Human Pellucide Zone 3 Monoclonal Antibody on Expression of Bcl-2 and Bax in Follicle Granulosa Cells of Mice Ovary Natalina, Riny; Nurseta, Tatit; Winarsih, Sri
Journal of Tropical Life Science Vol 8, No 2 (2018)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (393.255 KB) | DOI: 10.11594/jtls.08.02.09

Abstract

Pellucide zone 3 (ZP3) involves in fertilization mechanism. Moreover, antibody of ZP3 can develop to inhibit egg and sperm interaction. This study aims to determine the effect of hZP3 (mab-hZP3) monoclonal antibody on the expression of Bcl-2 and Bax in follicle granulosa cells of the mice ovary. Female mice BALB/c were divided into 12 groups which consisted of control and experimental treatment group. Each group was added with 30% of total mice as error sample (1 mice). Each groups were treated differently: 50 µl adjuvant Al(OH)3 in 50 µl Tris HCl, 20 µg Mab-hZP3, 40 µg Mab- hZP3, and 60 µg Mab-hZP3. Each group was dissected at day 10, 15 and 20. Measurement of Bcl-2 and Bax was performed with immunohistochemistry. Data was analyzed by Two-Way ANOVA. There was no significant effect of Mab-hZP3 administration in various doses on Bcl-2 (p=0.0825), and Bax (p=0.836). There was no significant effect of administration of Mab-hZP3 in time (p=0.807), neither on Bcl-2 expression (p=0.088) and Bax (p=0.227). The lowest Bcl-2 level was found in dose of 60 µg in day 15. There was no significant effect of Mab-hZP3 in various doses and time (p=0.691), neither to Bcl-2 and Bax. Such results obtained due to the specificity of a monoclonal antibody that recognizes specific antigen. Mab-hZP3 is proposed as immunocontraception for women causing no disturbance of folliculogenesis.
Mental Health Resilience Among Santri: A Salutogenic Perspective on Psychological Well-Being in Pesantren: A Salutogenic Perspective on Psychological Well-Being in Pesantren Ratodi, Muhamad; Zubaidah, Tien; Legawati; Natalina, Riny
Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Vol. 13 No. SI2 (2025): Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Educat
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jpk.V13.ISI2.2025.101-107

Abstract

Background: Mental health is a vital although insufficiently examined component of student well-being at pondok pesantren (Islamic boarding schools). Pesantren offer organized religious instruction and discipline, although they also pose distinct psychological issues. Objective: This study examines the mental health resilience of santri at Pondok Pesantren Darussalam Martapura utilizing Antonovsky’s Salutogenic Model. Methods: A qualitative case study methodology was employed, utilizing semi-structured interviews, participant observations, and document analysis involving 40 respondents, comprising santri, ustadz, and administrators emphasizing comprehensibility, manageability, and meaningfulness as protective variables Results: The results indicate that pesantren cultivate resilience via faith-based coping mechanisms (82%), peer social support (74%), and organized routines (68%). Nonetheless, 62% of santri experience stress attributed to stringent discipline, while merely 32% have access to professional psychological services, underscoring deficiencies in mental health support. Although faith imparts a significant sense of purpose (81%), it does not entirely alleviate stress, since 43% continue to endure chronic psychological suffering. Conclusion: The research conclude that incorporating mental health education, flexible disciplinary systems, and organized counseling services within pesantren can improve resilience while upholding religious principles. These findings enhance the broader dialogue on mental health promotion within faith-based educational environments and advocate for a comprehensive approach to student well-being.
PEMBERDAYAAN KELOMPOK SUAMI SIAGA PADA PERILAKU PERAWATAN KEHAMILAN (ANC) UNTUK PENCEGAHAN KOMPLIKASI KEHAMILAN USIA DINI DI WILAYAH PUSKESMAS BUKIT RAWI Legawati, Legawati; Natalina, Riny
EJOIN : Jurnal Pengabdian Masyarakat Vol. 2 No. 1 (2024): EJOIN : Jurnal Pengabdian Masyarakat, Januari 2024
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/ejoin.v2i1.2167

Abstract

Teenage pregnancy (early age) is one of the important problems in the 21st century. There are more than 16 million children in the world born to mothers aged 15-19 years. Indonesia is one of the regions with the highest presentation of early marriage in the world with a rank of 37 and the second highest in ASEAN. Central Kalimantan Province is ranked second in early pregnancy, with an increasing incidence of pregnancy complications based on data reported by one of the Referral Hospitals in Central Kalimantan Province. The evaluation was carried out using questionnaires on knowledge in the prevention of pregnancy complications. There was an increase in husbands' knowledge after empowerment, before empowerment was carried out there were 2 people (10%) in the good category, 12 people (60%) in the sufficient category and there were 8 people (30%) who were included in the less category. After the formation of the standby husband group, there was an increase in knowledge in the good category of 17 people (85%), in the sufficient category of 2 people (10%) and in the category of less than 1 person (5%). Husband empowerment can increase husband's knowledge in early detection of pregnancy complications. The establishment of an early pregnancy pregnancy alert group requires monitoring and supervision from the Puskesmas Bukit Rawi.
(Re)visiting the recommendations of Joint Committee on Reducing Maternal and Neonatal Mortality performance in rural areas in Central Kalimantan, Indonesia Oktaviani , Oktaviani; Natalina, Riny
GHMJ (Global Health Management Journal) Vol. 5 No. 1 (2022)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-51600

Abstract

Analisis Faktor Pemilihan Tempat Persalinan di Wilayah Kerja UPT Puskesmas Tangkiling: Analysis Factor for Selection of Maternity Places in the Work Area of UPT Puskesmas Tangkiling Setyaningsih, Eni; Hatini, Erina Eka; Natalina, Riny
Jurnal Surya Medika (JSM) Vol. 9 No. 3 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i3.6471

Abstract

Selain masa kehamilan, komplikasi dan kematian Ibu maternal dan bayi baru lahir sebagian besar terjadi pada masa persalinan. Penelitian ini bertujuan untuk mengetahui faktot-faktor yang berhubugan dengan pemilihan tempat persalinan. Metode penelitian yang digunakan analitik dengan pendekatan crossectional. Hasil penelitian ada hubungan antara riwayat antenatal care (p=0,026), pendapatan (p=0,004) dan dukungan keluarga (p=0,000). Tidak ada hubungan antara umur (p=0,004), pendidikan (p=0,344), status bekerja (p=0,524), paritas (p=0,531) dan jarak (p=0,688). Dengan adanya penelitian ini diharapkan dapat memberikan motivasi pada masyarakat untuk lebih memahami pentingnya persalinan di fasilitas kesehatan.
Co-Authors A.A. Ketut Agung Cahyawan W Hatini, Erina Eka Legawati Legawati Legawati, Legawati Muhamad Ratodi Oktaviani , Oktaviani Setyaningsih, Eni Tatit Nurseta