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HUBUNGAN ANTARA AKTIVITAS BELAJAR KELOMPOK DENGAN INDEKS PRESTASI MAHASISWA SEMESTER 6 FAKULTAS KEDOKTERAN UNIVERSITAS HANG TUAH SURABAYA TAHUN AJARAN 2017/2018 Handajani, Fitri; Hapsari, Kinanti; Garianto, Efyluk
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 2 (2019): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i2.1070

One of the active learning methods is to do a study group. Researcher is interested in research on the correlation between study group activities and student?s grade, so that students can find learning methods which may influence academic outcomes and facilitate learning, especially the medical students. This observational analytic study was carried out with a cross sectional design. The data of this study were obtained from the answers to the respondent's questionnaire in the Medical Faculty of Hang Tuah University, Surabaya. The sample in this study were semester 6 students of the 2017/2018 academic year at the Faculty of Medicine, University of Hang Tuah Surabaya (130 respondents). Based on the Spearman correlation statistical test between study group activities with the 6th semester students grade point, the significance of the correlation between study group activities and the 6th semester students grade point is 0.687. With a value of ? = 0.05, means p> ?, it can be concluded that the correlation between the two variables is not significant so that H0 accepts and H1 is rejected. So, there is no correlation between study group activities with 6th semester grade point. There is no correlation between study group activities and the 6th semester students grade point in the Faculty of Medicine, Hang Tuah University Surabaya.

Hubungan antara Konsumsi Kopi dengan Gejala Gastroesophageal Reflux Disease (GERD) Alika Putri Saraswati; Efyluk Garianto; Mulyarjo
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 1 No. 3 (2021): Februari
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Introduction: Gastroesophageal Reflux Disease (GERD) is a condition that develops when there is the retrograde flow of gastric contents causing some symptoms or complications. One of the risk factors for GERD is the habit of consuming coffee, which has become a trend in everyday life without realizing it. Purpose: The purpose of this study was to determine the relationship between coffee consumption and symptoms of GERD. Method: This research is an analytic observational study using a cross-sectional study design with a sample size of 86 people. Results: The results showed that most respondents were women with a total of 66 people (73.3%). Of the 86 respondents, 55 people (64%) had coffee consumption habits and 31 people (36%) did not. Respondents who did not have the possibility of suffering from GERD were 74 people (86.0%) and those who had the possibility of suffering GERD were 12 people (14.0%). Data analysis using the Spearman correlation test showed no significant relationship (p = 0.428) between the frequency of coffee consumption and symptoms of GERD. Of the 55 respondents who consumed coffee, 12 respondents (21.8%) consumed ready-to-drink liquid coffee, 19 respondents (34.5%) consumed ground instant coffee, and 24 respondents (43.6%) consumed ground/brewed coffee. Discussion: Data analysis using the Spearman correlation test showed no significant relationship (p = 0.193) between the type of coffee consumed and the symptoms of GERD. The conclusion of this study is that there is no significant relationship between coffee consumption and GERD symptoms in students of the Faculty of Medicine, University of Hang Tuah Surabaya, class 2016-2018.

Pengaruh Pengetahuan Hygiene Saat Menstruasi Terhadap Kejadian Fluor Albus pada Siswi Kelas 8 dan 9 di SMPN 1 Sidoarjo FAIZAH ALDA SARASWATI; ANNISA ULLYA RASYIDA; EFYLUK GARIANTO
HANG TUAH MEDICAL JOURNAL Vol 19 No 2 (2022): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v19i2.318

Personal hygiene was very important, especially for young women who were menstruating. Poor hygiene could cause symptoms or diseases, especially those that could attack the female reproductive organs. One of the symptoms due to not maintaining personal hygiene during menstruation was vaginal discharge. However, every woman had experienced vaginal discharge or fluorine albus. Fluor albus was divided into 2, namely physiological or normal vaginal discharge and pathological or abnormal vaginal discharge. The purpose of this study was to analyze the effect between hygiene knowledge during menstruation and fluor albus incidence on 8th and 9th grade students 1 Sidoarjo. This study used an observational analytic design by means of cross sectional data collection. The number of research subjects was 78 students with the sampling technique using consecutive sampling. Data collection was conducted by distributing questionnaires online via Google form (gform) site aimed at the research sample. The results showed that the majority of respondents in this study had sufficient knowledge of hygiene during menstruation as many as 47 respondents with a percentage of 60% and as many as 43 respondents with a percentage of 55% experienced pathological or abnormal fluor albus. Furthermore, a statistical test was conducted using Chi-square showing that the influence between variables had a significant value of 0.604 (p >α). The conclusion of this study showed there is no effect, between hygiene knowledge during menstruation and fluor albus incidence on 8th and 9th grade students at SMPN 1 Sidoarjo.

HUBUNGAN MOTIVASI TEMAN SEBAYA DENGAN PERILAKU KONSUMSI BUAH DAN SAYUR PADA MAHASISWA FAKULTAS KEDOKTERAN rosabella salsa ayu; Efyluk Garianto; Budiarto Adiwinoto; Annisa Ullya Rasyida
Jurnal Kesehatan Masyarakat Vol 10, No 5 (2022): SEPTEMBER
Publisher : Fakultas Kesehatan Masyarakat Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkm.v10i5.34355

The phenomenon of dietary habit that is more common among college students currently is fast food, because of its popularity than other types of food. The data showed that the highest level of fast food consumption occurred among students, including university students. This research was aimed at the students of Medical Faculty at Hang Tuah University, Surabaya, because of the tight lecture schedule, often affected the dietary habit and tended to choose foods that were less nutritious. This research aimed at determining the relationship between peer motivation and fruit and vegetable consumption behavior among students of the Medical Faculty 2018, Hang Tuah University, Surabaya. This research applied an observational analytic design through data collection by cross sectional. The numbers of research subjects were 96 students by the sampling technique using purposive sampling. Data collection was conducted by distributing online questionnaires through the jotform website which aimed at the research sample. The data that has been collected showed that the respondent's sense of motivation from peers was classified as sufficient (64.6%), continued well (22.9%) and less (12.5%). The results of the fruit and vegetable consumption behavior of the respondents showed that most of them had a good level (87.5%) and those who were less (12.5%). The data was analyzed by the Spearman`s Rho correlation test. It showed that there was a significant relationship between peer motivation and fruit and vegetable consumption behavior (p = 0.007).

Potential Effect of Phlorotannins in Brown Algae for Antidiabetic Therapy: Molecular Docking Approach Renagupita, Melani Sinastri; Rahadianto, Rahadianto; Garianto, Efyluk; Setianingsih, Herin
Makara Journal of Science Vol. 27, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

This study aims to manifest the effect of the active compound phlorotannins in brown algae on decreasing insulin resistance by analyzing the predicted interaction between phlorotannins and protein tyrosine phosphatase 1B (PTP 1B) and estimating the pharmacokinetics and toxicity of the active compound for type 2 diabetes mellitus (DM) therapy. This type of research uses an in silico study to test the effect of using phlorotannins as an active compound in brown algae against PTP 1B inhibition. Starting from preparing materials, i.e., downloading the three-dimensional structure of phlorotannins via PubChem and PTP 1B via RSCB PDB (PDB 1A5Y), molecular docking using Molegro Virtual Docker 5, molecular visualization using PyMol and Discovery Studio, and predicting pharmacokinetics and toxicity via pkCSM have been conducted. Here, the phlorotannins include phloroglucinol, dioxinodehydroeckol, eckol, phlorofucofuroeckol-A, dieckol, 7-phloroeckol, and 6,6′-bieckol. In addition, Ertiprotafib and S-phosphocysteine are used here as the comparison controls for docking validation. All phlorotannins can bind to PTP 1B at the same binding site with drug control. Experimental results revealed that phlorotannins–PTP 1B produces lower energy than complex S-phosphocysteine–PTP 1B (−266.8 kJ/mol), which acts as a control here. However, phloroglucinol–PTP 1B produces (−208 kJ/mol) under the same condition. Compared with the drug control Ertiprotafib (−322.8 kJ/mol), the lower bond energy is owned by phlorofucofuroeckol-A (−370.6 kJ/mol), 7-phloroeckol (−328 kJ/mol), dieckol (−331.8 kJ/mol), and 6.6'-bieckol (−341 kJ/mol). Furthermore, phlorotannins are very well absorbed in the intestine. According to Lipinski’s rule, active compounds, such as phloroglucinol, eckol, and dioxinodehydroeckol have high potential as a drug. Phlorotannins are nontoxic against hepatocytes and have fewer side effects than drug control. Based on the obtained data, use of the active compound phlorotannins in brown algae can decrease insulin resistance, which can be employed as adjunctive therapy in type 2 DM.

HUBUNGAN ANTARA AKTIVITAS BELAJAR KELOMPOK DENGAN INDEKS PRESTASI MAHASISWA SEMESTER 6 FAKULTAS KEDOKTERAN UNIVERSITAS HANG TUAH SURABAYA TAHUN AJARAN 2017/2018 Handajani, Fitri; Hapsari, Kinanti; Garianto, Efyluk
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 2 (2019): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i2.1070

One of the active learning methods is to do a study group. Researcher is interested in research on the correlation between study group activities and student’s grade, so that students can find learning methods which may influence academic outcomes and facilitate learning, especially the medical students. This observational analytic study was carried out with a cross sectional design. The data of this study were obtained from the answers to the respondent's questionnaire in the Medical Faculty of Hang Tuah University, Surabaya. The sample in this study were semester 6 students of the 2017/2018 academic year at the Faculty of Medicine, University of Hang Tuah Surabaya (130 respondents). Based on the Spearman correlation statistical test between study group activities with the 6th semester students grade point, the significance of the correlation between study group activities and the 6th semester students grade point is 0.687. With a value of α = 0.05, means p> α, it can be concluded that the correlation between the two variables is not significant so that H0 accepts and H1 is rejected. So, there is no correlation between study group activities with 6th semester grade point. There is no correlation between study group activities and the 6th semester students grade point in the Faculty of Medicine, Hang Tuah University Surabaya.

Expression of HMGB1 and NF-κB in Fetal Membranes of Premature Rupture of Membranes Sudiarta, Ketut Edy; Khan, Joan; Aldinasyah, Monicha Zalzabilla; Garianto, Efyluk; Budiarti, Retno
Althea Medical Journal Vol 10, No 4 (2023)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v10n4.2911

Background: Inflammation, either sterile or infection-related, may lead to premature rupture of membranes (PROM). The non-histone nuclear proteins, high mobility group box-1 (HMGB1), and nuclear factor kappa-B (NF-κB) transcription factors have been extensively investigated in many disorders involving inflammatory reactions. This study aimed to determine the expression of HMGB1 and NF-κB in fetal membranes of PROM compared with non-PROM.Methods: This study was an analytical observational study with a case-control design, performed from November 2021 to January 2022, including 40 fetal membrane samples (20 PROM and 20 non-PROM), which were obtained from pregnant women treated in the emergency unit of a hospital in Surabaya from August to November 2019 using the non-probability sampling method. The HMGB1 and NF-κB expressions were examined using the immunohistochemical method and further viewed under a light microscope (400x magnification), then assessed by Image-J software. The values were then compared between PROM and non-PROM, and analyzed using the Mann-Whitney U test.Results: There was a significant difference (p<0.001) in the expression of HMGB1 and NF-κB in PROM and non-PROM for HMGB1 45.86± 14.21% vs. 8.50± 5.66% expression/mm2; and NF-κB 33.47±5.45% vs. 7.29±4.90% expression/mm2, respectively.Conclusions: PROM groups have significantly higher expression of HMGB1 and NF-κB s, indicating their higher activity and contribution to PROM.

The Relationship Between the Implementation of Complementary Feeding Guidelines and the Nutritional Status of Children Under Two Years Old in Jagir Village, Surabaya Audia Putri, Fany; Garianto, Efyluk; Purwatiningrum, Prijanti Eka; Sudiarta, Ketut Edy
Jurnal Kedokteran Meditek Vol 32 No 3 (2026): MEI
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v32i3.3538

Introduction: The WHO recommends implementing feeding rules early in life to prevent child malnutrition. Providing good complementary foods requires attention to timeliness, adequate nutrition, safety and responsive delivery. Objective: This study aims to determine the relationship between the application of complementary feeding guidelines and the nutritional status of children under 2 years of age in Kelurahan Jagir Surabaya. Methods: An observational-analytic, cross-sectional study was conducted in 15 Integrated Health Service Post. 91 Mothers and children aged 6-24 months were selected using a purposive sampling method. The research instrument used anthropometric measurement data and questionnaires. This study analyzed the data using Spearman's rho correlation test (p < 0.05). Results: Spearman's rho analysis showed a relationship between the application of complementary feeding rules and the nutritional status indices BB/U and BB/PB (p < 0,001). However, there was no relationship between the application of complementary feeding rules and the nutritional status of the TB/U index (p = 0.307). The application of complementary feeding rules is associated with weight-for-age and weight-for-height status, but not with height-for-age, which reflects chronic malnutrition. Conclusion: These findings emphasize that the application of Basic Feeding Rules contributes to better weight gain in infants and young children, reinforcing the importance of pediatricians and health workers in complementary feeding education and counselling as a promotive and preventive measure in pediatrics. Thus, education and guidance for parents and health workers to improve complementary feeding practices are paramount to support improvements in children's nutritional status.

Associated Factors for Non-Communicable Diseases: A Comprehensive Analysis of Mental, Behavioral, Biological, and Sociodemographic Determinants Wienta Diarsvitri; Siti Isfandari; Lutfah Rif’ati; Efyluk Garianto
Media Publikasi Promosi Kesehatan Indonesia Vol. 9 No. 9 (2026)
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v9i9.11006

Introduction: Non-communicable diseases (NCDs) are the leading cause of death and disability in Indonesia, placing a growing burden on the healthcare system and economy. This study examined the sociodemographic and health-related factors associated with NCDs among adults aged 35 years and older, using cross-sectional data from the national health survey. Methods: This study was a secondary analysis of the 2018 Indonesian Basic Health Research, a national survey that employed systematic two-stage random sampling. The analysis included 177,919 adults aged 35 years and older. Complex-sample multivariable binary logistic regression was used to identify factors associated with NCDs. Adjusted odds ratios (aORs) with 95% confidence intervals (CIs) were estimated after adjustment for potential confounders. Results: Individuals aged ≥55 years had twice the odds of reporting NCDs compared with younger adults (aOR: 2.025; 95% CI: 1.888–2.172). Participants presenting four metabolic syndrome (MetS) components had more than fivefold higher odds of NCDs (95% CI: 4.822–7.153). Individuals with mental health conditions (MHCs) had 2.6-fold higher odds of NCDs than those without MHCs. Former smokers had more than twice the odds of NCDs compared with current smokers. Being male, employed, and in the highest spending group were independently associated with 1.3- to 1.5-fold higher odds of NCDs. In contrast, engaging in physical activity at or below the World Health Organization (WHO)-recommended level was associated with lower odds of NCDs. Conclusion: Older age, MetS, MHCs, former smoking, male sex, employment, and higher socioeconomic status were independently associated with increased odds of NCDs, whereas physical activity was associated with lower odds. The strong association between MetS and NCDs highlights the importance of early metabolic risk screening and integrated interventions addressing metabolic health, mental health, smoking cessation, and physical activity to reduce the burden of NCDs.

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