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Effect of Omega-3 Supplementation on Major Adverse Cardiovascular Events (MACE): A Systematic Review Aisy, Annesyia; Martineta, Meriza; Sari, Dina Keumala; Sitorus, Esther Reny Deswani
Buletin Farmatera Vol 7, No 2 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v7i2.9038

Abstract

Abstract: Major adverse cardiovascular events (MACE) are the most relevant outcome in cardiovascular secondary prevention because they are the main cause of mortality and morbidity in patients with cardiovascular disease. Due to the contrasting results between studies, omega-3 supplementation is believed to have cardioprotective effects, but its significance in reducing MACE is still in question. This study aims to determine the effect of omega-3 supplementation on the prevention of MACE. A literature search was carried out on several databases from September 820, 2021. Selection of literature is done through the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flowchart. Literature that is eligible was then assessed qualitatively. We compared the hazard ratio of each key outcome of interest, which was included in the primary and secondary end-point of each study. Among 2049 publications found from the initial literature search, 6 publications were included in this study. The analysis showed a significant reduction in cardiovascular risk in participants with a high dose of pure EPA. Studies with a lower dose of omega-3 that contains a combination of EPA and DHA did not provide similar significant results. The use of high-dose omega-3 supplementation with pure EPA content can significantly reduce
Hubungan asupan diet dengan penanda inflamasi pada penyandang obesitas Martineta, Meriza; Sari, Dina Keumala; Tala, Zaimah Z; Lubis, Nenni Dwi Aprianti
Buletin Farmatera Vol 6, No 2 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i2.6460

Abstract

Obesity is a body condition caused by an energy imbalance that is closely relatedto diet. Obese people experience chronic low-grade inflammation in the body that can lead tochronic disease due to the production of inflammatory markers from adipose tissue, one ofwhich is the acute phase protein C-reactive protein (CRP), which is closely related to diet.The purpose of this study was to determine the relationship between dietary intake andinflammatory markers (high sensitivity C-reactive protein, hs-CRP) in obese people. Therewere 34 men and women aged 19-59 years with BMI 25.0 kg/m2 tested for hsCRP blood andassessed dietary intake using the food frequency questionnaires (FFQ) method. Therelationship between dietary intake and hsCRP was assessed using the Spearman correlation.Intake of calories, protein, fat, carbohydrates, fiber, PUFA, and cholesterol did not have asignificant relationship with hsCRP (p 0.05). Dietary intake is not associated with hsCRP.
A Nutrition Education for Productive Aged Women to Improve Knowledge in Preventing Stunting in Indonesia Meriza Martineta; Nasution, Fitriyani; Lubis, Nenni Dwi Aprianti; Tala, Zaimah Z.; Sari, Dina Keumala
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 6 No. 2 (2021): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (272.705 KB) | DOI: 10.32734/abdimastalenta.v6i2.5943

Abstract

Background: stunting is one of the double burden health problem in Indonesia and the education during the first 1000 days of life is the most important determining factor. The aim of this study was to improve knowledge in preventing stunting. Methods: 50 women aged 19–59 years were giving a questionnaires before and after nutrition education has been performed. The effect of nutrition education was analyzed using Wilcoxon test. Results: there was a significant change of median score between pretest and posttest (p <0.05). Conclusion: Nutrition education was successful in improving knowledge of productive aged women in reducing stunting.