Article Per Year (5 Year)
p-Index From 2021 - 2026
0.817
P-Index
This Author published in this journals
All Journal Jurnal Zarah JOPS (Journal Of Pharmacy and Science) Jurnal Farmasi Klinik - Best Practice (JFKlin)
Purwanggana, Agus
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
SINTESIS SENYAWA 1,5-BIS(3’-ETOKSI-4’-HIDROKSIFENIL)-1,4-PENTADIEN-3-ON (EHP) DENGAN BAHAN BAKU ETIL VANILIN MUTU TEKNIK Mulatsari, Esti; Mumpuni, Esti; Purwanggana, Agus; Rasdianti, Putri
Jurnal Zarah Vol 9 No 1 (2021): Jurnal Zarah
Publisher : Fakultas Keguruan dan Ilmu Pendidikan, Universitas Maritim Raja Ali Haji

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31629/zarah.v9i1.2184

Abstract

Selama ini, sintesis senyawa 1.5-bis (3'-etoksi-4'-hidroksifenil)-1,4-pentadien-3-on (EHP) menggunakan etil vanillin kualitas pro analisis sebagai bahan baku. Dalam penelitian ini, dilakukan sintesis EHP dengan etil vanilin kualitas teknis sebagai bahan baku. Tujuan dari penelitian ini adalah memperoleh rendemen yang tinggi dengan karakteristik EHP yang sama dengan hasil sintesis menggunakan etil vanillin pro analisis akan tetapi biaya produksi lebih rendah. EHP merupakan senyawa analog kurkumin dengan mengubah gugus metoksi menjadi etoksi dan diketon menjadi monoketon. Metode sintesis menggunakan reaksi kondensasi aldol dengan variasi waktu kondensasi. Karakterisasi dan identifikasi senyawa hasil sintesis dilakukan menggunakan metode spektrofotometri. Hasil penelitian menunjukkan bahwa rendemen optimum yang diperoleh adalah 73,23% dalam waktu kondensasi 7 hari. Proses karakterisasi dan identifikasi menunjukkan bahwa senyawa yang disintesis berwarna hijau kecoklatan dan memiliki aroma aromatik, titik leleh 105,2-109,8 °C, Faktor retardasi (Rf) 0,68 dengan uji Kromatografi Lapis Tipis, serapan maksimum 310 dan 278,50 nm dengan uji kromatografi UV-Vis, vibrasi pada bilangan gelombang 3354,38 cm-1; 2979,82 dan 2931,60 cm-1; 1576.99 cm-1; 1672,51 cm-1; 838,59 dan 631,78 cm-1 dengan uji spektrofotometri Inframerah dan persentase area kemurnian dengan uji densitometri 76,69% dan persentase rendemen 51,16 %. Hasil ini menunjukkan karakteristik dan rendemen yang sama dibandingkan dengan EHP yang disintesis menggunakan etil vanilin kualitas pro analisis sebagai bahan baku dengan persentase rendemen yang lebih rendah.
The Demineralization Optimization for Chitosan Synthesis from Crab Shell Waste (Portunus pelagicus) Sari, Intan Permata; Mulatsari, Esti; Mumpuni, Esti; Purwanggana, Agus
JURNAL FARMASI DAN MAKANAN Vol 7 No 2 (2024): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i2.4653

Abstract

Chitosan, gelatin, albumin, and sodium alginate are examples of natural polymers that are often utilized as a basis material for polymeric nanoparticles. The deacetylation of chitin molecules produces the formation of chitosan. Chitin, protein, CaCO3, MgCO3, and astaxanthin pigment are all found in crab shells. Crab shell is an undervalued potential waste. Despite the fact that copious crab shell waste can be used to produce raw materials and industrial products. According to the findings of Mohadi et al (2014), chitosan was extracted with a yield of 70.71% and a deacetylation degree of 76.6%. Previous research on optimizing chitosan synthesis has involved changing the base reagent at the deacetylation stage. The results showed that a 50% concentration of KOH reagent produced the best chitosan properties. Another study on the synthesis of chitosan from crab shells got a yield of 70.4%, and the following analysis showed that this high yield is due to the amount of calcium. Therefore, demineralization in the synthesis of chitosan from crab shells must be optimized. The calcium content was measured after optimization with various solvent concentration variations. The best demineralization optimization results use 3 M hydrochloric acid with a decrease in calcium content of 97.75%.
Evaluation Of The Use Of Antidiabetic Drugs For Geriatric Patients With Type 2 Diabetes Mellitus In Outpatient Care At Fatmawati Hospital, South Jakarta In 2023. Mola, Maria Melda; Purwanggana, Agus; Subhan, Ahmad; Widyastuti, Anak Agung Arie
Jurnal Farmasi Klinik Best Practice Vol 4 No 2 (2025): Jurnal Farmasi Klinis Best Practice Volume 4 No. 2 Desember 2025
Publisher : RSUP Fatmawati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58815/jfklin.v4i2.68

Abstract

Diabetes mellitus is a non-communicable disease that has a large prevalence and is increasing every year in Indonesia. Evaluation of the use of antidiabetic drugs aims to ensure that patients with diabetes mellitus use antidiabetic drugs appropriately. This study is an observational study with retrospective descriptive analysis using patient medical record data. In this study, an evaluation was carried out on outpatient type 2 diabetes mellitus geriatric patients with a total of 200 patients based on PERKENI in 2021 with an accuracy standard of 100%. Evaluation of drug use is divided into 3 parameters, namely the right indication, the right drug, and the right dose. Based on the analysis of demographic data, most patients are at the age of 60-69 years and are female. Based on clinical data analysis, patients with the highest level of diabetes are type 2 diabetes mellitus without comorbidities or complications. Based on the results of the evaluation, the most common pattern of drug use is monotherapy. Based on the evaluation results, the right indication was obtained for 200 patients (100%), the right drug for 178 patients (89%) and the right dose for 199 patients (99.5%). Based on Hemoglobin A1c, FBS, PGB and RBGS, 188 patients (94%) had controlled diabetes. In this study, it can be concluded that there are still discrepancies in the use of antidiabetic drugs in outpatient type 2 diabetes mellitus geriatric patients at Fatmawati General Hospital in 2023.
EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN PNEUMONIA ANAK RAWAT INAP DI RSUP FATMAWATI JAKARTA TAHUN 2023 dosi, sari; PURWANGGANA, AGUS; SUBHAN, AHMAD; LATUPEIRISSA, DEBBIE
Jurnal Farmasi Klinik Best Practice Vol 4 No 2 (2025): Jurnal Farmasi Klinis Best Practice Volume 4 No. 2 Desember 2025
Publisher : RSUP Fatmawati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58815/jfklin.v4i2.72

Abstract

Co-Authors Ahmad Subhan Debbie Latupeirissa, Debbie dosi, sari Esti Mumpuni, Esti intan permata sari Mola, Maria Melda Mulatsari, Esti Rasdianti, Putri Widyastuti, Anak Agung Arie