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Effectiveness of Soursop Leaf Extract (Annona muricata l.) on IL-6 Levels in Mammary Sprague dawley Female Rats Induced by Staphylococcus aureus Purnamasari, Feby; Yulianty, Risfah; Latief, Syamsa
Unnes Journal of Public Health Articles in Press
Publisher : Universitas Negeri Semarang in cooperation with Association of Indonesian Public Health Experts (Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/ujph.v0i0.30904

Abstract

  Research this aiming for analyze effectiveness extract leaf soursop could take effect to IL-6 levels at mammae rat female Sprague Dawley induced Staphylococcus aureus. Research this use type research Experiment Moot or quasi-experimental design with the design of the Post-test Only Control Group Design by looking at the 3th and 6th day IL-6 levels after induction bacteria Staphylococcus aureus and giving treatment on mammae rat female Sprague Dawley. Taking sample blood done at eye rat 2 times with examination elisa kit. Data analyzed with use Hock and Post test followed by the Mann Whitney test . Research results to show that not there is difference IL-6 levels at group control (?=0,062 > ? =0,05) and group antibiotics (?=0,0514 > ? =0,05). On group leaf soursop (?=0.037 < ? =0,05) and group antibiotics + leaves soursop and on group control (?=0.030 < ? =0,05) to show there is difference levels IL-6. Value mean on group soursop 7.50 ± 1.74 pg/ml day to3, and 7.50 ± 1.74 1 pg/ml day 6. Value mean on group soursop + antibiotics 7.46 ± 26t.66 pg/ml Day 3, and 4.73 ± 1.36 pg/ml day 6. The implication of this study is that soursop leaf extract or combination of antibiotic + soursop leaf extract can be as a complementary therapy for mastitis caused by the bacteria Staphylococcus aureus. Keywords: Extract Leaf Soursop, Levels IL-6, Rat Sprague Dawley Females
Identifikasi Senyawa Aktif dari Ekstrak Daun Sirsak (Annona muricata L.)dengan Perbandingan Beberapa Pelarut pada Metode Maserasi Purnamasari, Feby
Window of Health : Jurnal Kesehatan Vol 4 No 3 (Juli 2021 )
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33368/woh.v4i03.588

Abstract

Soursop (Annona muricata L) is one of the native tropical fruit plants used to treat headaches, hypertension, coughs, asthma, and sedatives. Of the many medicinal plants, soursop leaves are used traditionally to treat inflammation. This study aims to determine the content of active compounds contained in soursop leaf extract with several solvents in the maceration processThe extraction method used in this research is the maceration method using 70% ethanol as a solvent. The extract obtained is then evaporated using a rotary evaporator until thickened, then dried with the help of a water bath. The resulting viscous extract was put into a portion of porcelain and the extract was weighed. The phytochemical tests that were carried out were saponins, flavonoids, alkaloids, tannins and steroids. The results of this study from the test, it was known that the soursop leaf extract sample with positive methanol solvent contained several active compounds in the form of flavonoids, saponins, tannin alkaloids, and steroids. The conclusion of The implication of this research is soursop leaf extract with active compounds in the form of flavonoids, saponins, and tannins which have the ability as antibacterial, antioxidant, anti-inflammatory, and inhibit bacterial growth or even die, and are able to prevent cancer.Researchers concluded that the soursop (Annona muricata L.) leaf extract contains active compounds in the form of alkaloids, tannins, saponins, steroids, flavonoids. The bioactive compounds contained in the soursop leaf extract can inhibit the growth of pathogenic bacteria so that they can be used as complementary anti-inflammatory and antibacterial therapies.
GAMBARAN KEJADIAN HIPEREMESIS GRAVIDARUM DI BIDAN PRAKTEK MANDIRI ST. NILAWATI S.ST Purnamasari, Feby
Journal of Borneo Holistic Health Vol 3, No 2 (2020): Journal Of Borneo Holistic Health
Publisher : Fakultas Ilmu Kesehatan, Universitas Borneo Tarakan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35334/borticalth.v3i2.1672

Abstract

Penelitian ini bertujuan untuk mengetahui gambaran Kejadian Hiperemesis Gravidarum Berdasarkan Umur Ibu, Umur kehamilan Ibu, dan Gravida ibu di Bidan Praktek Mandiri ST. Nilawati S.ST. Penelitian ini adalah jenis penelitian survey dengan metode pendekatan deskriptif yang bermaksud memberikan gambaran tentang kejadian Hiperemesis Gravidarum pada ibu hamil. Pengambilan sampel dengan cara Non Random Sampel (Purposive Sampling) Adalah metode dengan menggunakan kriteria yang telah dipilih oleh peneliti dalam memilih. Kriteria yang ditentukan oleh peneliti yaitu ibu hamil dengan muntah yang terus menerus, nafsu makan yang berkurang, berat badan menurun. Data yang dikumpulkan berupa data sekunder yang diperoleh dengan mempelajari catatan atau laporan dan buku register di Bidan Praktek Mandiri ST.Nilawati S.ST. Data dianalisis dengan Analisis data yang dilakukan adalah analisis deskriptif dengan rumus dan Pengolahan data dilakukan secara manual dalam bentuk tabel frekuensi dan presentasi dengan penjelasan tabel dalam naskah atau narasi. Hasil penelitian menunjukkan bahwa adi kesimpulannya terdapat 51 (68%) kasus dengan kejadian hiperemesis gravidarum, yang berisiko tinggi berdasarkan umur ibu yaitu umur 20 - 35 tahun, lebih banyak terjadi pada gravida 1 dan 3, dan terjadi pada umur kehamilan 16 minggu.
Perbedaan Perawatan Tali Pusat Terbuka Dan Perawatan Tali Pusat Tertutup Dengan Efektifitas Pelepasan Tali Pusat Purnamasari, Feby
Journal of Borneo Holistic Health Vol 4, No 2 (2021): Journal Of Borneo Holistic Health
Publisher : Fakultas Ilmu Kesehatan, Universitas Borneo Tarakan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35334/borticalth.v4i2.2062

Abstract

Bayi memerlukan pemantauan ketat dan perawatan yang dapat meningkatkan kesempatan menjalani masa transisi yang baik terhadap kehidupannya di luar uterus. Salah satunya perawatan tali pusat. Tali pusat dapat merupakan pintu masuk bagi infeksi ke tubuh bayi.Tingginya angka kematian bayi antara lain disebabkan asfiksia, BBLR, infeksi tali pusat (Tetanus neonatorum), congenital, dan lain-lain. Tujuan dalam penelitian ini adalah untuk mengetahui adakah perbedaanantara perawatan tali pusat terbuka dan perawatan tali pusat tertutup tentang efektifitas pelepasan tali pusat di BPM Nila Pangkep.Penelitian ini metode eksperimenmenggunakan desain non equivalent time sampel design dengan pendekatan sampling systematis, penelitian ini memiliki jumlah responden 33 bayi dengan tekhnik pengambilan probability sampling. Data dalam penelitian ini didapat dengan melakukan pengamatan dan intervensi langsung pada setiap responden.Hasil penelitian dengananalisis data yang digunakan adalah Uji T (Indepedent samples test) dengan tingkat kemaknaan α = 0.05 jika p α 0.05 artinya terdapat pengaruh perawatan tali pusat terbuka dan perawatan tali pusat tertutup tentang efektifitas pelepasan tali pusat atau perawatan dengan teknik terbuka lebih cepat waktu pelepasan tali pusatnya dibandingkan dengan perawatan teknik tertutup.
Effectiveness Treatment of perineal wounds with compresses soaked in Betadine Purnamasari, Feby; Nurhidayah, Nurhidayah
Journal Midwifery Jurusan Kebidanan Politeknik Kesehatan Gorontalo Vol 9, No 1 (2023): March
Publisher : Politeknik Kesehatan Kementrian Kesehatan Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jm.v9i1.596

Abstract

The postpartum infection could have come from a wound infection experienced by the perineum. It is caused by wound incisions experienced infections and a tear of the birth canal or tear of the perineum. Perineal care is an effort to provide comfort for women who have given birth to avoid infection. The purpose of this research is to investigate the effectiveness of the use of betadine compress not given betadine on healing wounds in the perineum. The kind of research is quantitative using experimental design spring. Samples are to be taken as many as 30 people that is 15 people to the control group and 15 people to the case. This study was conducted from September -November 2022. The research results show there is no difference between the healing of wounds in the perineum control compress betadine with clusters of cases that do not compress betadine (the test Mann Whitney U p-value = 0,129 > 0,05) so that it can be concluded that both compress and non compress betadine and it is the same with betadine have a chance to heal in good
Sosialisasi Penerapan Aplikasi Android Pemantauan Tumbuh Kembang Anak Guna Mencegah Stunting di Dusun Kampala Desa Bonto Matene Kec. Marusu Kab. Maros Purnamasari, Feby; Astuti, Fanni; Selvia, Selvia
Jurnal Pengabdian Kesehatan Vol 7, No 1 (2024): Jurnal Pengabdian Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM) STIKES Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31596/jpk.v7i1.296

Abstract

Stunting adalah kondisi tinggi badan seseorang lebih pendek dibanding tinggi badan orang lain pada umunya (yang seusia). Stunting merupakan masalah kesehatan yang banyak ditemukan di Indonesia balita yang mengalami stunting di Indonesia sebanyak 24,4% pada 2021. Upaya pencegahan stunting salah satu nya dengan Kegiatan pengabdian kepada masyaarkat melalui penyuluhan dan sosialisasi penerapan aplikasi android pematauan tumbuh kembang anak untuk mencegah stunting di Dusun Kampala, Desa Bonto Matene, Kab. Maros dengan sasaran sebanyak 100 ibu yang memiliki anak balita. Kegiatan sosialisasi penerapan aplikasi android tumbuh kembang anak bertepatan dengan kegiatan posyandu warga. Pengabdian kepada masyarakat berisi kegiatan sosialisasi, penyuluhan, pelatihan aplikasi android tumbuh kembang anak terhadap bidan desa, kader, dan masyarakat dalam hal ini para ibu yang memiliki anak balita. Kegiatan yang dilaksanakan mendapat respon positif dari bidan desa, kader, dan masyarakat, pada saat penyuluhan dan sosialisasi pelatihan penerapan aplikasi android pemantau tumbuh kembang anak berlangsung, terjadi interaksi komunikasi yang cukup intensif.
The Consequences of Bullying: Analyzing Its Effects on Student Achievement and Psychological Well-Being M, Syahruddin; Pongpalilu, Fien; Aisyah, Sitti; Maing, Rosmawati Abdul; Purnamasari, Feby
Al Qalam: Jurnal Ilmiah Keagamaan dan Kemasyarakatan Vol. 19, No. 2 : Al Qalam (Maret 2025)
Publisher : Sekolah Tinggi Ilmu Al-Qur'an (STIQ) Amuntai Kalimantan Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35931/aq.v19i2.4833

Abstract

Bullying has become a widespread issue in schools, with significant consequences for the victims. This study aims to explore the detrimental effect of bullying on students' academic achievement and stress levels. the study used mixed method approach, combining quantitative and qualitative data.A quantitative approach was employed, with data collected from 223 students at SMA Negeri 1 Pangkep using a Likert scale instrument. The findings reveal that bullying behavior, which encompasses students' thinking, feelings, attitudes, actions, and responsibility, is generally in the "good" category. However, the study also found a significant negative correlation between bullying and student achievement, as well as a positive correlation between bullying and student stress levels. The qualitative results found that bullying effects the students in learning and concentrate at school. This study underscores the importance of addressing bullying in schools to support student well-being and academic success. These results highlight the importance of addressing bullying in schools to ensure a safe and supportive learning environment for all students.
Android Application for Determining Growth and Development of Children Aged 0-5 Years using The Denver II Test Purnamasari, Feby; Selvia, Selvia
jitek Vol 10 No 2 (2023): Maret 2023
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v10i2.1032

Abstract

Health services in the form of information technology are needed to advance health services. Applications for child development are very necessary during the pandemic because of the limitations of direct visits by health workers to residents' homes, so an android application is needed as a screening method to determine child growth and development so that it can detect developmental delays in children from an early age. This study uses the Denver II test to design an android application to determine the growth and development of children aged 0-5 years. The design of the application system starts with observations and interviews, after which the process of designing and making an offline-based android application programming system is carried out. This application has been tested pretest and posttest on 30 mothers who have children aged 0-5 years. The Wilcoxon test carried out these results with a 0.000 <0.005, so there is a difference between the pretest and posttest knowledge results. The conclusion is that parents can use this application to monitor the growth and development of children aged 0-5 years