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All Journal Jurnal Kedokteran Brawijaya Journal of Issues in Midwifery KESANS : International Journal of Health and Science Jurnal Pengabdian Masyarakat Bangsa
Lovita, Agnestia Naning Dian
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Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Energy Health Professions Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Pengaruh Relaktasi Suplementer Dikombinasikan dengan Pijat Oksitosin dan Aromaterapi Lavender terhadap Peningkatan Berat Badan Bayi di Malang Raya ariani, dewi; Mastuti, Ni Luh Putu Herli; Hastuti, Nur Aini Retno; Lovita, Agnestia Naning Dian
Journal of Issues in Midwifery Vol 1, No 2 (2017)
Publisher : Journal of Issues in Midwifery

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.024 KB) | DOI: 10.21776/ub.JOIM.2017.001.02.10

Abstract

Di Indonesia ada banyak ibu yang tidak dapat menyusui bayinya karena berbagai alasan. Berbagai upaya dilakukan agar ibu dapat menyusui bayinya kembali, salah satunya dengan relaktasi suplementer dikombinasikan aromaterapi lavender dan pijat oksitosin. Tujuan penelitian ini adalah mengetahui pengaruh relaktasi suplementer, aromatherapy lavender dan pijat oksitosin terhadap peningkatan berat badan bayi di Malang Raya. Quasi Experiment dengan rancangan penelitian Randomized Post Test Only Control Group Design dilakukan pada ibu yang menginginkan kembali menyusui bayinya dengan usia bayi ≤ 6 bulan. Sampel dibagi dalam 4 kelompok : relaktasi suplementer (kontrol), relaktasi suplementer dan aromaterapi lavender, relaktasi suplementer dan pijat oksitosin, relaktasi suplementer dan kombinasi (aromaterapi lavender + pijat oksitosin). Perlakuan diberikan sejak hari pertama intervensi sampai dinyatakan berhasil melakukan relaktasi. Variabel yang diukur adalah peningkatan berat badan bayi. Hasil analisis pada variable peningkatan berat badan bayi tidak menunjukkan ada beda yang signifikan antar semua kelompok. Kesimpulan dari penelitian ini adalah perlakuan yang memberikan dampak terbaik adalah relaktasi suplementer metode kombinasi. Penelitian ini telah dinyatakan laik etik oleh Komisi Etik Penelitian Fakultas Kedokteran Universitas Brawijaya.
The Effect of Extra Virgin Olive Oil (EVOO) on Fetal Birth Weight in Preeclampsia Rat Model Silvani, Yulia; Maharani, Afniari; Lovita, Agnestia Naning Dian
Jurnal Kedokteran Brawijaya Vol 31, No 1 (2020)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (163.79 KB) | DOI: 10.21776/ub.jkb.2020.031.01.3

Abstract

Preeclampsia, as one of the most common pregnancy-specific diseases, causes high maternal-fetal morbidity and mortality in almost every country. Placental vascular abnormalities in preeclamptic women can cause chronic hypoxia and impaired fetal nutrition, so fetal growth retardation often occurs. EVOO has strong antioxidant effect is assumed to prevent nutritional disorders in the fetus. This study aimed to determine the effect of EVOO on fetal birth weight in a preeclampsia rat model. This research was laboratory research conducted in vivo with a Post Test Only Control Group design which consisted of five groups; negative control group, positive control group (pre-eclampsia rat model), dose 1, 2, and 3 groups that were preeclampsia rats given EVOO in 3 different doses (0.5 mL/day, 1 mL/day and 2 mL/day respectively). Blood pressure and proteinuria measurements were carried out at the 12, 15 and 19 day of pregnancy. After sacrificed, fetal weight was measured immediately using analytical balance. The result of this study showed that there was a significant reduction of fetal weight between negative control and positive control group (p=0.020), meanwhile no significant differences among positive control, dose 1 and dose 2 group (p=0.90 and p=0.142) but statistically significant to dose 3 group (p=0.005). EVOO administration increases fetal weight in doses group by its AA and DHA in Long-Chain Poly Unsaturated Fatty Acids (LCPUFA) within. The optimal dose of EVOO to increase fetal weight is 2 mL/day.
Optimalisasi Peran Kader Dalam Meningkatkan Derajat Kesehatan Masyarakat Melalui Pelatihan ToT Secara Berjenjang Setyowati, Dewi; Prasetyo, Budi; Lovita, Agnestia Naning Dian; Mufarokhah, Amelya Binti; Kusuma, Ira Nurwahyu; Prasetyo, Muhammad Rizkinanda
Jurnal Pengabdian Masyarakat Bangsa Vol. 2 No. 10 (2024): Desember
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v2i10.1825

Abstract

Pengabdian masyarakat ini bertujuan untuk membantu meningkatkan pelayanan kesehatan ibu dan anak di salah satu puskesmas di Surabaya melalui pemberdayaan masyarakat dengan melaksanakan pelatihan Training of Trainer (ToT) berjenjang bagi kader kesehatan untuk meningkatkan derajat kesehatan masyarakat. Pelatihan kepada kader kesehatan menggunakan metode deteksi dini kehamilan resiko tinggi yang telah disusun di dalam buku saku. Deteksi dini kehamilan resiko tinggi dilakukan dengan menggunakan metode sederhana yang dapat digunakan oleh masyarakat secara umum utamanya kader kesehatan. Kader kesehatan diajarkan cara pengukuran LILA, tekanan darah maupun pemeriksaan kesehatan sederhana lain yang menunjang pelaksanaan deteksi dini kehamilan resiko tinggi. Terdapat peningkatan pengetahuan kader dari awalnya rata-rata nilai pretest 87,72 mengalami peningkatan pada hasil post test dengan rata-rata nilai 91,6. Sehingga kegiatan ToT kader kesehatan dapat memberdayakan masyarakat dengan meningkatkan pengetahuan dan keterampilan kader dalam mendeteksi kehamilan resiko tinggi.
Modulation of Endothelin-1 and Placental Microvascular Diameter by Extra Virgin Olive Oil in Preeclampsia Rat Model Dian Lovita, Agnestia Naning; Silvani, Yulia; Maharani, Afniari; Riawan, Wibi
Jurnal KESANS : Kesehatan dan Sains Vol 4 No 11 (2025): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v4i11.422

Abstract

Introduction: Preeclampsia is linked to abnormal placental vasoconstriction and elevated endothelin-1 (ET-1). Polyphenols in Extra Virgin Olive Oil (EVOO) has antioxidant and vasoprotective properties, but its impact on ET-1 and placental microvasculature in preeclampsia is unclear. Objective: Investigate whether EVOO can attenuate hypertension and improve placental vascular health in preeclampsia. Method: 20 pregnant rats randomly assigned to five groups: normal (K−), preeclampsia model (K+), and three EVOO-treated groups (D1, D2, D3) receiving 0.5, 1, and 2 mL/day, respectively. Preeclampsia was induced with L-NAME, blood pressure was monitored on gestational days 12, 15, and 19. Placental ET-1 expression and microvessel diameter were assessed on day 19 using immunohistochemistry. Result and Discussion: EVOO treatment normalized blood pressure by gestational day 19. ET-1 expression increased with EVOO dose suggesting a role in vascular remodelling. Microvessel diameter improved in D1 and D2 but slightly decreased in D3. Conclusions: EVOO mitigates hypertension and enhances placental microvasculature in preeclampsia, with optimal effects at moderate doses.
Co-Authors Budi Prasetyo DEWI ARIANI Dewi Setyowati Hastuti, Nur Aini Retno Kusuma, Ira Nurwahyu Maharani, Afniari Mufarokhah, Amelya Binti Ni Luh Putu Herli Mastuti Prasetyo, Muhammad Rizkinanda Silvani, Yulia Wibi Riawan