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All Journal YARSI Medical Journal Junior Medical Journal
Wikaningrum, Riyani
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Religion Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

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POPULASI BAKTERI PADA FESES NEONATUS: PENELITIAN PENDAHULUAN Wikaningrum, Riyani; T Rochani, Jekti; Djannatun, Titiek; Widiyanti, Dian
Jurnal Kedokteran YARSI Vol 16, No 2 (2008): MEI - AGUSTUS 2008
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (177.301 KB) | DOI: 10.33476/jky.v16i2.236

Abstract

Recent published data have outlined a relationship between the composition of the intestinal microflora and allergic inflammation, autoimmunity, chronic bowel inflammation, psychiatric, cognitive and behavioral disturbances. Factors influencing intestinal microflora are environment, genetic predisposition, diet, age, diseases, drugs, stressor. This preliminary study is to establish local reference of microbial flora in neonates. This study included samples taken from 20 neonates, age 1 ? 7 days, from a private hospital in Jakarta. All samples were sent to microbiology laboratory without transport media and processed immediately. Bacteriological cultures for aerob and anaerob bacteria were performed according to the standard methods. Aerob and anaerob bacterial species were isolated from all samples, ranged 2 ? 5 species per sample. Enterobacteriaceae were found to be dominant isolates (25% - 75%); followed by Streptococcus anhaemolyticus (60%), Staphylococcus epidermidis (40%), Staphylococcus aureus (5%),Clostridium difficile (5%), Bacteroides fragilis (5%), Bifidobacterium sp. (10%), Lactobacillus sp. (5%) and yeast (5%). These data indicated that aerob and facultative anaerob bacteria were predominant in neonates. However Bifidobacterium, Lactobacillus and Clostridium difficile could be found. Further studies are needed to confirm this finding using larger number of samples and involving various age group.
Prevalensi dan Pola Kepekaan Bakteri Gram Negatif Multidrug Resistant dari Kultur Sputum Penyebab Infeksi Saluran Pernapasan Bawah Non-Tuberkulosis Tahun 2022-2023 Latar, Nurul Juwiyanti; Wikaningrum, Riyani; Armelia, Linda
Junior Medical Journal Vol. 3 No. 3 (2025): Maret 2025
Publisher : Fakultas Kedokteran Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jmj.v3i3.4603

Abstract

Pendahuluan: Infeksi saluran pernapasan bawah non-tuberkulosis sering disebabkan oleh berbagai macam bakteri Gram negatif seperti Klebsiella pneumoniae, Pseudomonas sp., dan Acinetobacter baumannii. Penggunaan antibiotik tanpa mengetahui bakteri penyebab dapat menyebabkan resistensi, termasuk multidrug-resistant (MDR), yang menyulitkan pengobatan serta meningkatkan risiko kematian. Tujuan penelitian ini untuk mengetahui prevalensi dan pola kepekaan bakteri Gram negatif multidrug-resistant dari kultur sputum penyebab infeksi saluran napas bawah non-tuberkulosis. Metode: Penelitian ini merupakan studi observasional deskriptif dengan desain kohort retrospektif yang dilakukan di rumah sakit swasta di Kota Bekasi dari Juni 2022 hingga Desember 2023. Hasil: Didapatkan 72 isolat (88,9%) adalah bakteri Gram negatif MDR, sebanyak 47 pasien (67,1%) adalah laki-laki dengan mayoritas usia lebih dari 28 hari - 18 tahun (57,1%), 54,3% pasien meninggal. Acinetobacter baumannii merupakan isolat terbanyak, isolat tersebut 100% resisten terhadap cefazoline, ceftazidime, ceftriaxone, cefepime, meropenem, gentamicin, dan ciprofloxacin. Kesimpulan: Pada penelitian ini ditemukan bakteri MDR Gram negatif terbanyak adalah Acinobater baumannii yaitu 19 isolat (26,3%). Bakteri MDR Gram negatif rata-rata mengalami resistensi tinggi terhadap golongan antibiotik penicillin dan cephalosporin. Dan sensitif terhadap tigecycline dan amikacin
Co-Authors Dian Widiyanti Latar, Nurul Juwiyanti Linda Armelia T Rochani, Jekti TITIEK DJANNATUN