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All Journal Insisiva Dental Journal : Majalah Kedokteran Gigi Insisiva Journal of Case Reports in Dental Medicine
Usman, Nur Asmi
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Dentistry Health Professions

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Tata Laksana Xerostomia Oleh Karena Efek Penggunaan Amlodipine: Laporan Kasus Usman, Nur Asmi; Hernawan, Iwan
Insisiva Dental Journal: Majalah Kedokteran Gigi Insisiva Vol 6, No 2 (2017)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/di.6284

Abstract

Pendahuluan: Xerostomia atau yang biasa disebut dengan sindroma mulut kering merupakan akibat dari penurunanatau tidak adanya flow saliva sehingga menyebabkan mukosa rongga mulut menjadi kering. Gejala-gejala yangtimbul berupa rasa rongga mulut terasa kering, rasa terbakar, tidak nyaman, kesulitan dalam menelan, gangguanpengecapan, dan rasa terbakar pada rongga mulut, bibir pecah-pecah dan terkelupas. Penggunaan obat-obatanmerupakan yang paling sering menyebabkan xerostomia. Obat-obatan itu dapat berupa antidepresan, antikolinergik,antispasmodik, antihistamin, antihipertensi, sedatif, diuretik, dan bronkodilator. Salah satu penyebab xerostomiaadalah penggunaan obat antihipertensi yaitu amlodipine, suatu golongan Calcium Channel Blockers (CCBs). Tujuan:untuk melaporkan tata laksana xerostomia disebabkan oleh penggunaan amlodipine. Kasus: pasien wanita berusia55 tahun datang dengan keluhan mulut terasa kering, air ludah terasa kental dan sulit menelan sejak 5 bulan yanglalu. Pasien berobat ke poli gigi Rumah Sakit kemudian dibersihkan karang giginya namun keluhan belum membaik.Pasien kembali berobat ke poli gigi Rumah Sakit 2 bulan yang lalu kemudian pasien dirujuk ke RSGM FKG Unair.Pasien memiliki riwayat hipertensi sejak 2 tahun yang lalu dan mengkonsumsi obat amlodipine 5 mg satu kali sehari.Tes sialometri menunjukkan saliva yang berbuih dengan hasil 0.03 ml/menit. Tata laksana: pemberian obat kumurchlorine dioxide dan dry mouth gel serta mengunyah permen karet mengandung xilitol. Kesimpulan: Penangananxerostomia dapat dilakukan dengan penggunaan obat kumur chlorine dioxide dan dry mouth gel dapat mengurangikeluhan mulut kering.
Manifestation of Multiple Oral Ulcerations and Facial Palsy in Patient with History of Typhoid Fever Nasrul, Adenia A.; Putri, Anggun Mauliana; Usman, Nur Asmi; Yusran, Ali; Israyani, Israyani; Indirayani, Indirayani
Journal of Case Reports in Dental Medicine Vol 7, No 1 (2025)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jcrdm.v7i1.249

Abstract

Objective: Typhoid fever is infectious disease caused by Salmonella typhi. Patients with typhoid fever might have several clinical manifestations, in addition, post-infection, patients are still at risk of experiencing posttreatment complications. The aim of this article is to report a case of multiple oral ulcerations in a post-typhoid fever patient to improve the knowledge and awareness of dentists in handling ulcer lesions cases in the oral mucosa, especially in patients with history of infectious diseases. Methods: An-54-year-old female came with the chief complaint of multiple painful ulcers on the oral mucosa since 3 days ago after following hospitalization for typhoid fever for 8 days. The patient typically experiences only 2 ulcers and healed without medication. Extral oral examination revealed the facial asymmetry on sinistra. The patient was prescribed dexame dexamethasone gargle and referred to neurologist. The hematology examination revealed the decreased hemoglobin and erythrocyte levels. The patient has also been diagnosed with Bell’s Palsy and treated with methylprednisolone. Therefore, the working diagnosis is Aphthous-like ulcers related to typhoid fever Result: Oral ulcers can occur in typhoid patients due to anemic condition that triggers malnutrition deficiency of vitamin B12, folic acid, and iron which causing damage to the oral mucosa, playing a role in triggering and worsening oral ulcers. Anemia in typhoid is caused by decrease of erythrocyte production in bone marrow due to infection leading to anemia. Conclusion: Multiple oral ulcers can be triggered by systemic condition, such as typhoid fever.
Co-Authors Ali Yusran, Ali Indirayani, Indirayani Israyani, Israyani Iwan Hernawan, Iwan Nasrul, Adenia A. Putri, Anggun Mauliana