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All Journal Journal of Case Reports in Dental Medicine
Ali Yusran, Ali
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Dentistry Health Professions

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Identifying oral macula with malignant potential and its etiology: A case report with literature review Rasdayanti, Nur; Usman, Nur A.; Sumintarti, Sumintarti; Harlina, Harlina; Yusran, Ali; Marlina, Erni; Putri, Andi AM.
Journal of Case Reports in Dental Medicine Vol 6, No 3 (2024)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jcrdm.v6i3.247

Abstract

Objective: This article aims to report interesting case of whole mouth pigmentation, including on patient full protheses.Methods: A 79-year old female came to dental clinic with a chief complaint of difficulty in swallowing. The patient felt no pain but is very uncomfortable due to impaired taste and a burning sensation in her mouth.  In addition, the patient's dentures were stained with a diffuse black-and-white coating indicating a long and chronic course event.  This complaint occurred for last 2 months, after a long history of being in and out from the hospital due to several illnesses.  Ongoing treatment of the patient include drug for chronic digestive diseases and hypertension. Results: The patients told to come back in 7 days with strict instructions to bring all hospital-related documents to rule out possible etiologic of the pigmentation.Conclusions: This interesting case concluded with working diagnosis of oral melanocarcinoma due to macula fast and massive spread and distribution. However, black-pigmentation on patient prothesis can lead to a strong suggestion that the trigger of those malignant possible triggered by a long-chronic un-treated candida infection.
Intra uterine device on the severity of recurrent aphthous stomatitis: A case report Anitasari, Merry; Marlina, Erni; Usman, Nur A.; Putri, Andi AM.; Israyani, Israyani; Yusran, Ali; Rahmi, Rahmi
Journal of Case Reports in Dental Medicine Vol 6, No 3 (2024)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jcrdm.v6i3.246

Abstract

Objectives:  This article aimed to report RAS with severe clinical form due to hormonal fluctuant triggered by Intra Uterine Device.Methods: A 26-year-old female patient came to Hasanuddin University Dental Hospital with complaints of continuous mouth ulcers since 1 year ago. Deep anamnesis revealed that the initial trigger of the unhealed ulcers incidentally happened at the same time after the patient installed an Intra Uterine Device (IUD) which also led to continuous menstruation in the past month leading to self-decision to have her IUD removed. Due to her clinically anemic condition, the patient was referred for routine blood examination with the result of lower red blood cells and hemoglobin which also contributed to the ulcer severity. Since the main cause of hormonal imbalance has been removed, supportive treatment uses vitamins to support the patient’s systemic condition which gives a good response.Conclusion: Recalcitrant and severe intraoral ulceration may be triggered by hormonal imbalance caused by IUD. Removal of these devices can help reduce oral complaints if the patient is on optimum health, otherwise, the background systemic needs to be improved.
Intra uterine device on the severity of recurrent aphthous stomatitis: A case report Anitasari, Merry; Usman, Nur A.; Marlina, Erni; Putri, Andi AM.; Israyani, Israyani; Yusran, Ali; Rahmi, Rahmi
Journal of Case Reports in Dental Medicine Vol 7, No 1 (2025)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jcrdm.v7i1.265

Abstract

Background: Recurrent aphthous stomatitis (RAS) is one of the most common oral mucosal diseases characterized by recalcitrant and painful ulcerations in the oral cavity. The pathogenesis remains uncovered, but several factors are thought to contribute, such as a hormonal imbalance due to puberty, a disease, contraceptive devices including Intra Uterine Device (IUD) for birth control, and un-coping stress.Objectives:  This article aimed to report RAS with severe clinical form due to hormonal fluctuant triggered by Intra Uterine Device.Case report: A 26-year-old female patient came to Hasanuddin University Dental Hospital with complaints of continuous mouth ulcers since 1 year ago. Deep anamnesis revealed that the initial trigger of the unhealed ulcers incidentally happened at the same time after the patient installed an Intra Uterine Device (IUD) which also led to continuous menstruation in the past month leading to self-decision to have her IUD removed. Due to her clinically anemic condition, the patient was referred for routine blood examination with the result of lower red blood cells and hemoglobin which also contributed to the ulcer severity. Since the main cause of hormonal imbalance has been removed, supportive treatment uses vitamins to support the patient’s systemic condition which gives a good response.Conclusion: Recalcitrant and severe intraoral ulceration may be triggered by hormonal imbalance caused by IUD. Removal of these devices can help reduce oral complaints if the patient is on optimum health, otherwise, the background systemic needs to be improved.
Manifestation of Multiple Oral Ulcerations and Facial Palsy in Patient with History of Typhoid Fever Nasrul, Adenia A.; Putri, Anggun Mauliana; Usman, Nur Asmi; Yusran, Ali; Israyani, Israyani; Indirayani, Indirayani
Journal of Case Reports in Dental Medicine Vol 7, No 1 (2025)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jcrdm.v7i1.249

Abstract

Objective: Typhoid fever is infectious disease caused by Salmonella typhi. Patients with typhoid fever might have several clinical manifestations, in addition, post-infection, patients are still at risk of experiencing posttreatment complications. The aim of this article is to report a case of multiple oral ulcerations in a post-typhoid fever patient to improve the knowledge and awareness of dentists in handling ulcer lesions cases in the oral mucosa, especially in patients with history of infectious diseases. Methods: An-54-year-old female came with the chief complaint of multiple painful ulcers on the oral mucosa since 3 days ago after following hospitalization for typhoid fever for 8 days. The patient typically experiences only 2 ulcers and healed without medication. Extral oral examination revealed the facial asymmetry on sinistra. The patient was prescribed dexame dexamethasone gargle and referred to neurologist. The hematology examination revealed the decreased hemoglobin and erythrocyte levels. The patient has also been diagnosed with Bell’s Palsy and treated with methylprednisolone. Therefore, the working diagnosis is Aphthous-like ulcers related to typhoid fever Result: Oral ulcers can occur in typhoid patients due to anemic condition that triggers malnutrition deficiency of vitamin B12, folic acid, and iron which causing damage to the oral mucosa, playing a role in triggering and worsening oral ulcers. Anemia in typhoid is caused by decrease of erythrocyte production in bone marrow due to infection leading to anemia. Conclusion: Multiple oral ulcers can be triggered by systemic condition, such as typhoid fever.
Early detection, better prognosis in oral squamous cell carcinoma: A case report Nisaa, Ihda R.; Usman, Nur A.; Putri, Andi AM.; Marlina, Erni; Israyani, Israyani; Yusran, Ali
Journal of Case Reports in Dental Medicine Vol 7, No 3 (2025)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jcrdm.v7i3.253

Abstract

Introduction: Misdiagnosed oral lesions can lead to delayed diagnosis and progression to malignancy, significantly impacting patient outcomes. Early detection of oral squamous cell carcinoma (OSCC) remains a significant challenge in clinical practice, particularly in cases with atypical presentation. We aim to highlight the importance of vigilance and early detection in improving prognose for patients with OSCC.Case Report: This case report discusses good progression of OSCC treatment in 43-year-old male who presented with a persistent ulcer on the ventrolateral tongue, initially attributed to trauma and misdiagnosed as a traumatic ulcer. Over nine months, the lesion progressively enlarged, with associated pain and induration, despite symptomatic treatment. The patient had a history of systemic conditions, along with previous tobacco use, which are recognized as risk factors for OSCC. Histopathological examination revealed keratinizing squamous cell carcinoma. Patient then treated with chemotherapy and showed significant progression on his tongue.Discussion: Early recognition of warning signs, such as non-healing ulcers with indurated borders, could have facilitated timely diagnosis and intervention. This case emphasizes the critical role of clinicians in identifying high-risk lesions, particularly in patients with systemic comorbidities or lifestyle-related risk factors. Regular oral health examinations, prompt biopsies, and multidisciplinary approaches are essential in reducing delays in diagnosing potentially malignant oral conditions.Conclusion: Clinicians must prioritize early evaluation and adopt a proactive approach in managing suspicious oral lesions to reduce the burden of advanced malignancies in oral health.
A rare case of recurrent aphthous ulcer associated with calcium channel blocker Ishak, Andi AQM.; Marlina, Erni; Usman, Nur A.; Putri, Andi AM.; Israyani, Israyani; Yusran, Ali; Nisaa, Ihda R.
Journal of Case Reports in Dental Medicine Vol 7, No 3 (2025)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jcrdm.v7i3.251

Abstract

Introduction: The most commonly used hypertension medications are calcium channel blockers (CCB). Their oral impact is well recognized for gingival enlargement, yet is very limited to another oral manifestations. Here, we reported a rare case of recurrent aphthous ulcer in a patient under CCB medication.Case Report: A 59-year-old male patient came to Hasanuddin University Dental Hospital with a chief complaint of recalcitrant ulcers on his mouth three weeks ago, which started to occur continuously for a year after the regular consumption of amlodipine. Intraoral examination demonstrated painful solitary white ulcer on the right ventral of the tongue and on the left buccal mucosa. The working diagnosis of recurrent aphthous ulcer et causa CCB was made. Management includes dexamethasone gargle, triamcinolone acetonide gel, and chlorhexidine gluconate, which improved significantly. The patient was suggested to do a consultation with his internist regarding drug substitution.Discussion: The incidence of oral ulcers induced by CCB is predicted to be related to immunological mechanisms. Any drug component triggers an exaggerated immune reaction directed at the surface of the epithelium, resulting in ulcer. The potential for such response depends on the drug's immunogenicity, exposure frequency, and administration route.Conclusion: Practitioners should consider the possibility of oral ulceration triggered by a specific drug, especially if any therapy does not exhibit improvement. Moreover, dental literature must explore the association between CCB and oral ulcers more since this issue has limited explanations.
Co-Authors Anitasari, Merry Erni Marlina, Erni Harlina Harlina Indirayani, Indirayani Ishak, Andi AQM. Israyani, Israyani Nasrul, Adenia A. Nisaa, Ihda R. Putri, Andi AM. Putri, Anggun Mauliana Rahmi Rahmi Rasdayanti, Nur Sumintarti Sumintarti, Sumintarti Usman, Nur A. Usman, Nur Asmi