Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal Jurnal Ilmiah Manuntung Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Siswanto, Eka
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Chemistry Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
UJI TOKSISITAS AKUT EKSTRAK ETANOL DAUN KEREHAU (Callicarpa longifolia Lam.) TERHADAP MENCIT PUTIH Siswanto, Eka; Sari, Desy Nur Indah; Supomo, Supomo
Jurnal Ilmiah Manuntung Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (279.893 KB) | DOI: 10.51352/jim.v1i2.24

Abstract

Leaves kerehau (Callicarpa longifolia Lam.) is one of the plants used for the treatment of malaria, ulcers, diarrhea, treatment after delivery, and fever, by drinking boiled water. Report usage and security kerehau leaves are still very few. The purpose of this study to determine the potential for acute toxicity by determining the value of LD50 (Lethal Dose 50) in 4 dose-rise that dose I, II, III, and IV of the ethanol extract of the leaves kerehau against this mice. The Research. Pharmacologically using experimental methods using a completely randomized design pattern is undirectional in the selection of test animals, They are 25 mice were divided into five groups (5 mice each group), with observed 4 hours to determine the toxic symptoms and continued observation every 24 hours for 7 days to see death. Results from this study show from 4 dose levels, dose group I = 16g / kg, group II = 8g / kg, group III = 4g / kg and group IV = 2g / kg and control = 0.5 ml Na-CMC. Symptoms namely the observation of behavior and neuromuscular but not on observations of the autonomic nervous, respiratory, gastrointestinal, and skin. LD50 value obtained is expressed by the LD50 (16g / kg) were categorized as practically non-toxic (> 15g / kg)
PEMANFAATAN EKSTRAK HERBAL TERHADAP PRODUKTIVITAS DAN MUTU AYAM PEDAGING SEBAGAI UPAYA KETAHANAN PANGAN DI KALIMANTAN TIMUR BERBASIS PETERNAKAN RAMAH LINGKUNGAN Supomo, Supomo; Siswanto, Eka; Ventyrina, Ine
Jurnal Ilmiah Manuntung Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (83.394 KB) | DOI: 10.51352/jim.v2i1.52

Abstract

Quality broilers become a serious problem for farmers. Many studies done to solve these problems, one of them by making use of natural materials. Some plants are known to have the ability to improve the quality of broilers as bitter, ginger and onions tiwai. This study aimed to determine the effect of ethanol extract of the herb on the quality of broilers. Subjects used is Strain Cobb broiler DOC. A total of 60 chickens were kept in a cage stage measuring 1.5 x 1.5 m for 30 days. Subjects were divided into five treatment where each treatment consisted of four tails. The experiment was conducted with three replications using a completely randomized design. Such treatment includes control (P0), the ethanol extract of sambiloto 0.02 % (P1), the ethanol extract of umbi bawang dayak 0.05 % (P2), the ethanol extract of temulawak 0,075 (P3), Product Imugas (P4). Quality parameters include coarse fat content and crude protein. The data obtained were statistically analyzed using analysis of variance (ANOVA). The results showed that the treatment of all types of ethanol extract of the herb can improve the quality of broilers compared to control (sig < 0.05), the type of treatment is best to P4. Quality parameters which include : crude protein and crude lipid. Levels of the protein, which is the highest in treatment P4 by 23.87% . Fat content, which is the lowest in treatment P4 of 10.50%
UJI AKTIVITAS EKSTRAK ETANOL GAMBIR (Uncaria gambir Roxb.) TERHADAP PENYEMBUHAN LUKA BAKAR PADA KULIT PUNGGUNG MENCIT PUTIH JANTAN (Mus musculus) Handayani, Fitri; Siswanto, Eka; Pangesti, Lintang Ayu Trisna
Jurnal Ilmiah Manuntung Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (357.793 KB) | DOI: 10.51352/jim.v1i2.25

Abstract

Gambir (Uncaria gambir Roxb.) contains flavonoids, tannins, saponins and alkaloids that can help in the healing process of burns on the back skin of mice. Gambir has been used for the treatment because it has the effect of antimicrobial and anti-inflammatory. Gambir is used by the people as a traditional medicine to treat burns.This research is experimental research. The object studied is the potential of gambir extract on healing burns of mice back skin. The number of mice used are 15 which divided into 5 groups: the positive control group (branded ointment), negative control group (vaseline flavum), group of gambir ethanol extract and vaseline flavum concentration of 25%, 35%, and 45%. Each group consisted of 3 mice.Backs of the mice induced using a heated solder which tip contained stainlees plate measuring 1x1 cm and placed for 2 seconds on the back skin of mice. The percentage of burns healing is obtained by calculating the surface area of the wound. The data were analyzed using ANOVA analysis followed by LSD test. The results showed that ethanol extract of gambir concentration of 25% with the healing burns percentage of (72.00%), the concentration of 35% (85.00%), and the concentration of 45% (88.67%) have activity on healing burns of back skin of mice. The results of data analysis using ANOVA showed that the data has significant differences with a significance value <0.05 is 0.000. LSD test results stated that each treatment group have significant differences with a significance value <0.05. It can be seen that with increasing dose will be followed by duration of burns healing
FORMULASI SEDIAAN TABLET EKSTRAK AKAR KUNING (Fibraurea tinctoria Lour.) SEBAGAI ANTIDIABETES Sa`adah, Hayatus; Supomo, Supomo; Siswanto, Eka; Kintoko, Kintoko; Witasari, Hardi Astuti
Jurnal Ilmiah Manuntung Vol 7 No 2 (2021): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i2.484

Abstract

There are many plants that have the potential to be developed into anti-diabetic herbal medicine. One of them is yellow root (Fibraurea tinctoria Lour.) that contains chemical compounds including alkaloids, flavonoids, tannins, saponins, steroids/triterpenoids. Its known that the administration of ethanolic extract of yellow root at doses of 50, 100 and 200 mg/kg BW can reduce blood glucose levels of rats with induced with alloxan. To increase the use of yellow root in food medicine, preparations were developed by formulating the extract in tablet dosage form. In this study, tablets were made with three formulas with different fillers, namely Avicel PH 101 and pregelatinized starch. The research was conducted experimentally using three formulas with varying concentrations of fillers with a ratio between Avicel PH 101 and and pregelatinized starch, namely formula I (1:0), formula II (0.5:0,5) and formula III (0:1). Furthermore, evaluation of granules which includes evaluation of flow time, angle of repose, compressibility, mass density and moisture content. The granules were compressed and evaluated for tablets including evaluation of weight uniformity, hardness, friability and tablet disintegration time. Based on the results of the study, it can be concluded that the variation of the filler did not affect the physical properties of the yellow root extract granules, but did affect the physical properties of the tablets. The results showed that the tablet that met all the requirements for the physical properties of the yellow root extract tablet was formula II with a combination of Avicel PH 101 and Pregelatinized Starch as fillers.
Co-Authors Hardi Astuti Witasari Hayatus Sa`adah, Hayatus Kintoko Kintoko Pangesti, Lintang Ayu Trisna Sari, Desy Nur Indah Supomo Supomo Ventyrina, Ine