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All Journal JURNAL KEDOKTERAN KOMUNITAS DAN TROPIK Grimsa Journal of Science Engineering and Technology
Sorisi, Angle Maria Hasthee
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Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Engineering Medicine & Pharmacology Physics

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Prevalensi infeksi cacing usus soil transmitted helminths pada orang dewasa di Sulawesi Utara Sorisi, Angle Maria Hasthee; Sapulete, Ivonny Melinda; Pijoh, Victor David
JURNAL KEDOKTERAN KOMUNITAS DAN TROPIK JKKT Volume 7 Nomor 2 (2019)
Publisher : UNIVERSITAS SAM RATULANGI

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Abstract

Worm disease or helminthiasis, is a disease caused by worms or helminths. Worms that occur are often caused by the Soil Transmitted Helminths (STH) worms, which are worms that are transmitted through the soil. Intestinal helminthiasis is one of the neglected infectious diseases (NIDs) and is still a public health problem in Indonesia. Worm disease is a disease that does not get enough priority in the Health Office program and data on intestinal helminthiasis infection is only limited to the population of school children. The absence of data on helminthiasis in adults in North Sulawesi shows the need for increased awareness about this because not only in children, intestinal helminthiasis can also infect high-risk adults such as people living in slums and poor sanitation, people with immunodeficiency, and people who do a lot of activities with the land. Population density, geographical conditions, and climate also affect intestinal worm transmission. Given the above, it is necessary to conduct research to determine the percentage of STH intestinal helminthiasis infections in adults. This research was conducted in the Clinical Parasitology Laboratory for sample examination. The sample in this study was stool in patients who had stool examination in the Parasitology laboratory. This type of research is analytic descriptive with cross-sectional approach. A total of 40 stool samples, examined using the direct method and examined under a microscope. From the results of laboratory tests, 20 samples (50%) were positively infected by worms. The types of worms found in the sample were Ascaris lumbricoides, Hookworm, Trichuris trichiura, Strongiloides stercoralis. Hookworm infection is the most common type of helminthiasis which is found in 35% of all samples examined followed by Stongiloides stercoralis at 7.5%, Ascaris lumbricoides 5%.
Comparative Assessment of Microscopy and RDTs in Diagnosing Plasmodium vivax Mesaulawan, Septyarini; Sorisi, Angle Maria Hasthee; Tuda, Josef Sem Berth
Grimsa Journal of Science Engineering and Technology Vol. 3 No. 1 (2025): April 2025
Publisher : Graha Primera Saintifika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61975/gjset.v3i1.71

Abstract

Plasmodium vivax is the primary cause of malaria in Indonesia in 2023, particularly in areas with low to moderate endemicity. To reduce malaria transmission, rapid and accurate diagnostic tools are essential for early detection. Microscopic examination remains the gold standard, but the limited availability of trained microscopists and facilities hinders its effectiveness in endemic areas. The Rapid Diagnostic Test (RDT) based on pLDH, such as SD Bioline® Malaria Ag Pf/Pan®, offers rapid results and ease of use, which are beneficial in resource-limited settings. However, performance data for this RDT in Indonesia remains limited. This study evaluates the field performance of SD Bioline® compared to microscopic examination as the reference standard for P. vivax diagnosis. The study involved 62 EDTA blood samples from suspected malaria patients at the Parasitology Laboratory of the Faculty of Medicine, Sam Ratulangi University, from July 2022 to December 2024. Microscopic examination revealed 54 positive cases (87.1%), while SD Bioline® detected 50 positive cases (80.6%). The sensitivity and specificity of SD Bioline® were 92.6% and 100%, respectively, with a negative predictive value (NPV) of 66.6% and a positive predictive value (PPV) of 100%. The results suggest that SD Bioline® demonstrates good sensitivity and specificity for detecting P. vivax in endemic areas. However, false negatives require microscopic confirmation. Combining RDT with microscopy can improve diagnostic accuracy and support Indonesia's malaria elimination efforts by 2030.
Co-Authors Mesaulawan, Septyarini Pijoh, Victor David Sapulete, Ivonny Melinda Tuda, Josef Sem Berth