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All Journal e-CliniC PHARMACON JURNAL BIOMEDIK
Wiyono, Weny I.
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology

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Cost of Illness Pasien Hipertensi Rawat Inap di RSUP Prof. Dr. R. D. Kandou Manado Lolo, Widya A.; Wiyono, Weny I.; Mpila, Deby A.
e-CliniC Vol. 12 No. 3 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i3.58444

Abstract

Abstract: Besides causing systemic damage to organs, hypertensive disease also has an impact on the health economy sector (double burden disease). This study aimed to determine the cost of illness of hypertensive inpatients and its suitability with INA-CBG's tariff. This was an analytical and observational study with a cross-sectional designh. Data were collected retrospectively from the medical records of hypertensive inpatients registered as members of Jaminan kesehatan Nasional (National Health Insurance) from January to June 2024 and from financial department of Prof. Dr. R. D. Kandou Hospital Manado. Pharmaeconomic analysis was used based on hospital perspective and prevalence approach. The data were analyzed using one sample t-test to compare the congruence between cost of illness and INA-CBG’s tariff. There were 30 inpatients in this study, consisting of 10 males and 21 females. The results showed that the difference between total cost of illness and INA-CBG’s tariff was Rp.76,403,811. The one sample t-test showed that the congruence between cost of illness and INA-CBG’s tariff was significantly different based on the p-values of each code, as follows: 0.001 (I-17-14-I), 0.000 (I-17-14-II), and 0.000 (I-17-14-III). In conclusion, the total cost of illness of hypertensive inpatients at Prof. Dr. R. D. Kandou Hospital was Rp. 251,287,311 with an average per patient of Rp. 8,376,244. Moreover, overall there is a significant difference between cost of illness and INA-CBG's tariff. Keywords: cost of illness; hypertensive inpatients; Indonesian Case-based Group    Abstrak: Penyakit hipertensi bukan hanya menyebabkan kerusakan sistemik di organ namun juga berdampak pada sektor ekonomi kesehatan (double burden disease). Penelitian ini bertujuan untuk mengetahui besaran terapi pasien hipertensi (cost of illness) dan kesesuaiannya dengan tarif INA-CBG’s. Jenis penelitian ialah observasional analitik dengan desain potong lintang. Data pasien hipertensi Jaminan kesehatan Nasional (JKN) rawat inap diperoleh secara retrospektif dari Bagian Rekam Medik dan Bagian Keuangan RSUP Prof. Dr. R. D. Kandou Manado periode Januari-Juni 2024. Analisis farmakoekonomi dilakukan dengan kajian berdasarkan perspektif rumah sakit dimana kategori biaya dalam perhitungan cost of illness menggunanakan biaya medis langsung dengan pendekatan secara prevalensi. Data analisis uji beda menggunakan one sample t-test untuk mengetahui perbandingan biaya cost of illness dengan tarif INA-CBG’s. Hasil penelitian mendapatkan 30 pasien sebagai sampel, terdiri dari 10 laki-laki dan 21 perempuan. Besaran selisih antara cost of illness dengan tarif INA-CBG’s sebesar Rp. 76.403.811. Kesesuaian antara cost of illness dengan tarif INA-CBG’s menggunakan one sample t-test berbeda bermakna dengan nilai p masing-masing kode ialah 0,001 (I-17-14-I); 0,000 (I-17-14-II); dan 0,000 (I-17-14-III). Simpulan penelitian ini ialah total cost of illness pasien hipertensi rawat inap RSUP Prof Dr. R. D. Kandou sebesar Rp. 251.287.311 dengan rerata per pasien sebesar Rp. 8.376.244. Terdapat perbedaan bermakna antara cost of illness dan tarif INA-CBG’s. Kata kunci: cost of illness; pasien hipertensi; Indonesian Case-based Group
Hubungan Kepatuhan Penggunaan Obat Antihipertensi dengan Kualitas Hidup Pasien Hipertensi Wagiu, Ariel E.; Wiyono, Weny I.; Mpila, Deby A.
e-CliniC Vol. 13 No. 1 (2025): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v13i1.58790

Abstract

Abstract: Hypertension is a condition where systolic and diastolic blood pressure exceeds values of 140 mmHg and 90 mmHg, respectively. Patient compliance related to the use of antihypertensive drugs is a major factor in improving the quality of life of hypertensive patients. This study aimed to determine the relationship between the level of compliance in consumption of antihypertensive drugs and the quality of life of hypertensive patients at Puskesmas Kawangkoan (public health center). This was an observational and analytical study with a cross-sectional approach. A total of 80 patients as samples were obtained using purposive sampling technique. Data on the level of compliance with drug use were obtained from the Morisky Medication Adherence Scale (MMAS-8) questionnaire and the Short-Form 36 (SF 36) questionnaire to measure quality of life in hypertensive patients. The results obtained 80 patients as samples. Data were statistically analyzed using the Spearman-rho test which showed a significant relationship between the level of compliance in drug consumption and the quality of life of hypertensive patients at Puskesmas Kawangkoan (p=0.000<0.05). In conclusion, there is a significant relationship between the level of compliance in antihypertensive drug consumption and the quality of life of hypertensive patients at Puskesmas Kawangkoan. Keywords: hypertension; medication adherence; quality of life.   Abstrak: Hipertensi adalah keadaan dimana tekanan darah sistolik dan diastolik melebihi nilai  140 mmHg dan 90 mmHg. Kepatuhan pasien dalam penggunaan obat antihipertensi merupakan faktor utama dalam peningkatan kualitas hidup pasien. Penelitian ini bertujuan untuk mengetahui hubungan tingkat kepatuhan penggunaan obat antihipertensi dengan kualitas hidup pasien hipertensi di Puskesmas Kawangkoan. Jenis penelitian ialah analitik observasional dengan desain potong lintang. Sampel penelitian diperoleh dengan teknik purposive sampling. Data tingkat kepatuhan penggunaan obat diperoleh dari kuesioner Morisky Medication Adherence Scale (MMAS-8) dan kuesioner Short-Form 36 (SF 36) untuk mengukur kualitas hidup pada pasien hipertensi. Hasil penelitian mendapatkan sebanyak 80 pasien sebagai sampel. Hasil uji Spearman-rho menunjukkan adanya hubungan bermakna antara tingkat kepatuhan penggunaan obat dengan kualitas hidup pasien hipertensi (p=0,000<0,05). Simpulan penelitian ini ialah terdapat hubungan bermakna antara tingkat kepatuhan penggunaan obat antihipertensi dengan kualitas hidup pasien hipertensi di Puskesmas Kawangkoan. Kata kunci: hipertensi; kepatuhan penggunaan obat; kualitas hidup
Identifikasi Drug Related Problems (DRPs) pada Pasien Penyakit Jantung Koroner di Instalasi Rawat Inap CVBC RSUP Prof. Dr. R. D. Kandou Manado Laloan, Carmelita; Wiyono, Weny I.; Mpila, Deby A.
e-CliniC Vol. 13 No. 2 (2025): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v13i2.60743

Abstract

Abstract: Patients with coronary heart disease (CHD) are prone to Drug Related Problems (DRPs) due to the many therapies received by patients. This study aimed to identify the prevalence of DRPs in each category of CHD patients. This was a descriptive and retrospective study using medical records of CHD patients during the period September-November 2023 who fulfilled the inclusion criteria. The results obtained 64 CHD patients as samples. There were 27 patients (42.19%) who had the potential to experience DRPs with 31 cases of DRPs in the identified DRPs categories including indications without therapy (77.41%) and therapy without indications (22.59%). There were no DRPs in the categories of ineffective drugs, dose too high, and dose too low. In conclusion, the therapy obtained by coronary heart disease patients in the CVBC inpatient installation of Prof. Dr. R. D. Kandou Hospital Manado still experienced DRPs, especially in the categories of indication without therapy and therapy without indication. Keywords: coronary heart disease; drug related problems    Abstrak: Pasien dengan penyakit jantung koroner (PJK) rentan mengalami Drug Related Problems (DRPs) karena terapi yang diterima pasien cukup banyak. Penelitian ini bertujuan untuk mengidentifikasi prevalensi kejadian DRPs pada setiap kategori dari pasien PJK. Jenis penelitian ialah deskriptif retrospektif dengan pengambilan data rekam medik pasien PJK yang memenuhi kriteria inklusi selama periode September-November 2023. Hasil penelitian mendapatkan 64 pasien PJK sebagai sampel. Terdapat 27 pasien (42,19%) yang berpotensi mengalami DRPs dengan 31 kejadian DRPs pada kategori DRPs indikasi tanpa terapi (77,41%) dan terapi tanpa indikasi (22,59%); tidak terdapat kejadian DRPs pada kategori obat tidak efektif, dosis terlalu tinggi, dan dosis terlalu rendah. Simpulan penelitian ini ialah terapi yang diperoleh pasien penyakit jantung koroner di instalasi rawat inap CVBC RSUP Prof. Dr. R. D. Kandou Manado masih mengalami kejadian Drug Related Problems, terutama pada kategori indikasi tanpa terapi dan terapi tanpa indikasi. Kata kunci: penyakit jantung koroner; drug related problems
Evaluasi Penggunaan Antibiotik pada Pasien Pneumonia di Bangsal Pediatri Manan, Nadine E.; Wiyono, Weny I.; Mpila, Deby A.
e-CliniC Vol. 13 No. 2 (2025): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v13i2.61015

Abstract

Abstract: Infectious diseases such as pneumonia are becoming more difficult to treat as antibiotics become less effective. This study aimed to evaluate the use of antibiotics in pneumonia patients in the pediatric ward of Robert Wolter Monginsidi Hospital Manado. This was a non-experimental conducted retrospectively using total sampling method, and the data were analyzed descriptively. The results obtained 89 pediatric patients with pneumonia from January to December 2023 as samples. The use of antibiotics with the right indication was 100%, the right patient was 100%, the right drug was 100%, and the right dose was 34.83%. In conclusion, the administration of antibiotics in pneumonia patients in the pediatric ward of Wolter Monginsidi Hospital Manado is appropriate for indications, appropriate for patients, and appropriate for drugs Keywords: evaluation of therapy; antibiotics; pneumonia; pediatric patients.    Abstrak: Penyakit-penyakit infeksi antara lain pneumonia menjadi semakin lebih sulit diobati karena antibiotik menjadi kurang efektif. Penelitian ini bertujuan untuk mengevaluasi penggunaan antibiotik pada pasien pneumonia di bangsal pediatrik Rumah Sakit Robert Wolter Monginsidi Manado. Metode penelitian ini bersifat non-eksperimental yang dilakukan secara retrospektif dengan pengambilan sampel secara total sampling, dan dianalisis secara deskriptif. Hasil penelitian mendapatkan 89 pasien pediatri dengan pneumonia pada periode Januari–Desember 2023 sebagai sampel. Didapatkan penggunaan antibiotik yang tepat indikasi sebesar 100%, tepat pasien sebesar 100%, tepat obat sebesar 100%, dan tepat dosis sebesar 34,83%. Simpulan penelitian ini ialah pemberian antibiotik pada pasien pneumonia di Bangsal Pediatrik Rumah Sakit Wolter Monginsidi Manado sudah tepat indikasi, tepat pasien, dan tepat obat. Kata kunci: evaluasi terapi; antibiotik; pneumonia; pasien pediatri
Co-Authors Alotia, Gerry S. Angkow, Leydia Antasionasti, Irma Baluntu, Dwi DEBY AFRIANI MPILA Gayatri Citraningtyas Gultom, Febryan Heedy Tjitrosantoso Jayanto, Imam Kawengian, Sartika I. Laloan, Carmelita Maalangen, Tiansi Manan, Nadine E. Manarimbing, Marina Mangaku, Albertian Marina Mamarimbing Maringka, Pingkan C. Pratiwi, Ageng I. Wagiu, Ariel E. Widya Astuty Lolo, Widya Astuty