Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Science: Indonesian Journal of Science
Darmawan, Muhammad Rahmat
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Chemistry Mathematics Physics Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Inhibitor Enzim sebagai Terapi Targeted dalam Kanker: Tinjauan Kimia Medisinal Darmawan, Muhammad Rahmat; Amin, Saeful
Science: Indonesian Journal of Science Vol. 2 No. 3 (2025)
Publisher : LPPI Yayasan Almahmudi bin Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/science.v2i3.257

Abstract

Cancer is a leading cause of global mortality, necessitating more effective and selective therapies. This study aims to evaluate the potential of enzyme inhibitors, particularly kinase inhibitors, as targeted therapy in cancer treatment. The methodology employed is an in vitro experimental design, testing against cancer cell lines MCF-7, A549, and HT-29. The results indicate that kinase inhibitors significantly reduce cancer cell viability with lower IC50 values compared to protease inhibitors. These findings underscore the greater potential of kinase inhibitors as a safer and more effective alternative cancer therapy. In conclusion, this research provides new insights into the use of enzyme inhibitors in cancer therapy and opens avenues for the development of new compounds that could enhance clinical outcomes in the future. It is recommended to explore the combination of enzyme inhibitors with other therapies and conduct clinical studies to evaluate their effectiveness in a broader patient population.
Co-Authors Saeful Amin, Saeful