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All Journal Journal of General Procedural Dermatology and Venereology Indonesia Jurnal Kedokteran Meditek
Melody Febriana Andardewi
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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The epidemiology of skin cancer at Dr. Cipto Mangunkusumo National Central General Hospital from 2014 to 2017 Larisa Paramitha Wibawa; Melody Febriana Andardewi; Inge Ade Krisanti; Riesye Arisanty
Journal of General - Procedural Dermatology and Venereology Indonesia Vol 4, No 1 (2019): December 2019
Publisher : Universitas Indonesia

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Abstract

Background: The incidence of skin cancer has been increasing over the past decades globally. At present, there is no valid national cancer data in Indonesia. The purpose of this study is to evaluate the increment of skin cancer cases at Dr. Cipto Mangunkusumo National General Hospital, Jakarta.Methods: In this retrospective descriptive study, we evaluated all pigmented skin tumor cases from June 2014 to June 2017. Data were obtained from the Department of Anatomical Pathology and medical records at Dr. Cipto Mangunkusumo National General Hospital. Data were compared with previous reports.Results: From 263 skin cancer cases, the most frequent skin cancer was basal cell carcinoma (BCC; 66.9%), followed by squamous cell carcinoma (SCC; 27.4%), and malignant melanoma (MM; 5.7%). Most of the skin cancer were predominantly in the female population. In BCC and SCC, most of the patients were within the age group above 60 years (n = 106 and 18, respectively). In MM, the incidence is greater in age group of 41–50 years (n = 5). For BCC and SCC, the distribution sites of lesions were mostly in sun-exposed areas, whereas the distribution sites of MM were mostly in non-sun-exposed areas. Median diameters of BCC, SCC, and MM were 2, 4, and 6.5 cm, respectively. There was an increase of BCC incidence from 1996 to 2017. Conclusion: In comparison with other types, the incidence of BCC in Dr. Cipto Mangunkusumo National General Hospital is increasing. A well-documented skin cancer registry is required to establish national data of skin cancer in Indonesia. Keywords: epidemiology, incidence, basal cell carcinoma, malignant melanoma, squamous cell carcinoma
Perkembangan Terapi Sistemik Pada Pruritus Melody Febriana Andardewi; Windy Keumala Budianti; Lili Legiawati; Yudo Irawan
Jurnal Kedokteran Meditek Vol 28 No 1 (2022): JANUARI-APRIL
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v28i1.2203

Abstract

Pruritus merupakan sensasi tidak nyaman yang mencetuskan keinginan untuk menggaruk. Sensasi tersebut disebabkan oleh berbagai hal, misalnya penyakit kulit, penyakit sistemik, atau idiopatik, gangguan psikiatri, serta penyakit neurologis. Pruritus menjadi masalah kesehatan karena dapat memberi dampak negatif terhadap kualitas hidup pasien. Pendekatan tata laksana pruritus diberikan secara bertingkat mulai dari terapi dasar, terapi target, dan terapi simtomatik. Pada kasus pruritus kronik yang refrakter maupun pruritus tanpa sebab yang diketahui, terapi simtomatik berperan besar dan dapat diberikan pada pasien tersebut. Tata laksana pada pruritus kronik saat ini banyak diteliti seiring dengan ditemukan berbagai mekanisme yang mendasari terjadinya pruritus. Sesuai dengan patofisiologi dari pruritus, terapi sistemik yang dikembangkan menargetkan pada reseptor spesifik di sistem saraf dan sistem imunitas yang berperan pada jalur sinyal pruritus. Berbagai terapi terbaru yang masih diteliti dalam uji klinis menunjukkan hasil yang menjanjikan dan berpotensi menjadi pilihan terapi pada pasien dengan pruritus kronik.
Co-Authors Inge Ade Krisanti Larisa Paramitha Lili Legiawati Lili Legiawati Riesye Arisanty Windy Keumala Budianti Yudo Irawan