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All Journal El-Hayah : Jurnal Biologi Jurnal Teknologi Laboratorium Prosiding Seminar Informasi Kesehatan Nasional
Azizah, Inas Hasna
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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In-vitro antibacterial activity of the seed extract of three member Artocarpus towards methicillin resistant Staphylococcus aureus (MRSA) Prastiyanto, Muhammad Evy; Azizah, Inas Hasna; Haqi, Hafizha Dara; Yulianto, Bagus Dwi; Agmala, Aulia Bella; Radipasari, Zhafira Dias; Astuti, Nita Ayu Dwi; Putri, Arifani Rahma
Jurnal Teknologi Laboratorium Vol 9 No 2 (2020): (In Progress)
Publisher : POLTEKKES KEMENKES YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29238/teknolabjournal.v9i2.237

Abstract

Methicillin-Resistant Staphylococcus aureus (MRSA) infections have created a critical need for the development of natural antibacterials from biological sources. This research aimed to investigate the antibacterial activity of the seed extract of three-member Artocarpus (Artocarpus heterophyllus, A. champeden and A. camansi) against MRSA which are the most prevalent causes of infections in patients. Crude seed extracts of three-member Artocarpus were evaluated for their antibacterial activity against MRSA. The antibacterial activity against MRSA of the three extracts was assayed in vitro by the agar well diffusion assay and agar microdilution method (Minimum inhibitory concentration [MIC] and Minimum bactericidal concentration [MBC]). The best antibacterial activity, calculated as a zone of inhibition and MIC, MBC values. The Crude seed extracts of three-member Artocarpus showed antibacterial activity against the MRSA in the agar well diffusion assay (1.5-9 mm inhibition diameter). The MIC value of extract showed at 15.62 mg/mL and the MBC value of seed extract of A. heterophyllus at 62.5 mg/mL, A. champeden at 31.25 mg/mL, A. camansi at 250 mg/mL. The data have revealed that all seed extracts have the potential to be developed as antibacterial agents, particularly against MRSA strain. Further in vivo research and discovery of mode action are needed to shed light on their antibacterial effects. Research on anti-MRSA of seed extract of Artocarpus against MRSA has not been reported. Studies on the antibacterial activity against MRSA can provide new information about the benefits seed of members of Artocarpus as a source of natural antibacterial.
Adsorption of Carbon Monoxide (CO) on ZSM-5 Membrane in Smoking Area Azizah, Inas Hasna; Mindhumalid, Tatut; Mukaromah, Ana Hidayati
El-Hayah : Jurnal Biologi Vol 6, No 2 (2017): EL-HAYAH (VOL 6, NO 2,March 2017)
Publisher : Department of Biology Science and Technology Faculty UIN Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/elha.v6i2.4533

Abstract

This research aimed to investigate the ability of ZSM-5 in absorbing cigarette smoke to reduce CO level in smoking area. The research method are according to Gao, 2011 and Mukaromah 2014. The results were characterized using x-ray diffraction (XRD), FTR and SEM. The absorbance test was conducted by placing the gauze absorbed into the enclosed space with volume 18.000 cm3containing CO from cigarette smoke. The research was reached the stage of inorganic and organic substances leaching and oxidized in electrochemistry in H2SO4 to 20%. Zeolite zsm-5 membrane has the ability to absorb CO with the decline in CO on the highest levels the surface area of 25 cm2 to the time contact 30 minutes is 0.50 %.
BIOMARKER PADA KANKER STEM SEL: LITERATURE REVIEW Ismawatie, Emma; Azizah, Inas Hasna; Maulani, Yulita
Prosiding Seminar Informasi Kesehatan Nasional 2023 : SIKesNas 2023
Publisher : Fakultas Ilmu Kesehatan Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/sikenas.vi.2851

Abstract

Sel punca kanker adalah sel tumor pemicu kanker. CSC terjadi karena kegagalan asimetris pada sel punca yang memicu tumorigenesis. CSC terkait dengan metastasis, perkembangan kanker dan resistensi terhadap terapi. Jalur pensinyalan terkait penanda terlibat dalam kejadian dan perkembangan tumor, dan memiliki dampak signifikan pada proliferasi, metastasis, dan invasi sel kanker, yang dapat digunakan sebagai target terapi molekuler yang potensial. Artikel ini akan membahas penanda pada Cancer Stem Cells. Makalah ini bertujuan untuk menemukan penanda sebagai target terapi di CSC.
Co-Authors Agmala, Aulia Bella Ana Hidayati Mukaromah Astuti, Nita Ayu Dwi Haqi, Hafizha Dara Ismawatie, Emma Maulani, Yulita Mindhumalid, Tatut Prastiyanto, Muhammad Evy Putri, Arifani Rahma Radipasari, Zhafira Dias Yulianto, Bagus Dwi