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HUBUNGAN ANTARA GAMBARAN HISTOPATOLOGI DENGAN JUMLAH LEUKOSIT PADA PENDERITA LIMFADENITIS TUBERKULOSIS DI NUSA TENGGARA BARAT TAHUN 2019 Alfaridzi, Muhammad; Lestarini, Ima Arum; Djannah, Fathul
Jurnal Kedokteran Vol 10 No 1 (2021): volume 10 nomor 1 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i1.453

Abstract

Background: Indonesia is the 3rd country with the highest incidence of tuberculosis (TB) in the world. 15% of TB cases are EPTB with 50% of them being lymphadenitis TB (LNTB). The histopathological features of the biopsy samples play an important role in the diagnosis of this disease by producing the images of WOG or POG. The number of leukocytes can describe the immune response in people with LNTB. Methods: This study is an observational analytic study with a cross-sectional approach. The data were obtained by documenting the medical records of LNTB patients who were treated at the RSUD Provinsi NTB and RSUD Kota Mataram in the January 2019 - February 2020 period. Results: The total number of research subjects is 51 people. In the histopathological features, 37 samples included WOG, and 14 samples included POG. On the leukocyte count, none of the patients had leukopenia, 39 patients had normal leukocyte counts and 12 patients had leukocytosis. The results of the Spearman correlation test obtained p = 0.005 and r = 0.384 Conclusion: There is a significant correlation between the histopathological features and the number of leukocytes in patients with LNTB in NTB in January 2019 - February 2020. The correlation is weak.
PEMANFAATAN SUSU SAPI DAN SUSU KEDELAI TERHADAP PENINGKATAN JUMLAH LIMFOSIT MENCIT JANTAN YANG TERPAPAR RADIASI SINAR X Yudha, Sagita; Dewilza, Nerifa; Alfaridzi, Muhammad
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 9 No. 3 (2023)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v9i3.805

Abstract

Radiasi yang digunakan dalam kesehatan memang memberikan manfaat yang lebih baik dibandingkan efek yang ditimbulkan, namun radiasi ini tetap memiliki efek sebagai karsinogen bagi organisme hidup terutama kadar limfosit dalam darah. Tujuan penelitian ini adalah untuk melihat peningkatan limfosit setelah terpapar radiasi Sinar-X dengan pemberian susu sapi dan susu kedelai (Susu Soya). Desain yang akan dilakukan pada penelitian ini adalah penelitian eksperimental laboratories dengan rancangan posstest only control group design. Peralatan yang dibutuhkan berupa Pesawat sinar X, Tabung reaksi, Buku dan alat tulis, Mikroskop Bahan habis bahan yang dibutuhkan seperti, Susu Soya, Susu sapi steril, 21 tikus jantan. Berdasarkan hasil penelitian melalui hasil uji statistik dengan menggunakan uji ANOVA One Way diperoleh nilai significant = 0,000 (p > 0,05) sehingga Ho ditolak dan Ha diterima, maka dapat disimpulkan bahwa terdapat perbedaan antara rerata jumlah limfosit pada mencit dengan pemberian susu sapi, susu kedelai, dan tanpa pemberian susu.