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All Journal Jurnal Ilmiah Edunomika (JIE) Journal of Functional Food and Nutraceutical
Wu, Ming-Chang
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Agriculture, Biological Sciences & Forestry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Nursing

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ANTI-INFLAMMATORY ACTIVITY OF PECTIC ENZYME-TREATED PECTIN ON LIPOPOLYSACCHARIDE-INDUCED RAW 264.7 CELLS Huang, Cian-Song; Li, Qiao-Lin; Lo, Diana; Wang, Yuh-Tai; Wu, Ming-Chang
Journal Akademik Universitas Swiss German Vol 1 No 1 (2019)
Publisher : Swiss German University & Perhimpunan Penggiat Pangan Fungsional dan Nutrasetikal Indonesia (P3FNI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (782.022 KB) | DOI: 10.33555/jffn.v1i1.14

Abstract

The purpose of this study was to investigate the ability and pathway of the pectic enzyme-treated (PET) pectin to inhibit the inflammation of macrophage RAW 264.7 induced by lipopolysaccharide. Results showed that PET-pectin produced from 1% substrate and 48 h reaction time had the highest antioxidative activity, thus these parameters were used to produce PET-pectin used in this study. PET-pectin showed no cell cytotoxicity to normal macrophage RAW 264.7 and reduce the nitrite secretion from LPS-induced RAW 264.7 by 20%. Finally, the expression of cytokines, including NO synthase (iNOS), nitric oxide (NO), cyclooxygenase-2 (COX-2), nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) and tumor necrosis factor (TNF-?) were analyzed by western blot. In the western blot method, it was found that iNOS, COX-2, NF-?B, TNF-? and other proteins that activated NO production had a downtrend. It was found that PET-pectin possess promising activity to mitigate the inflammatory response.
Perspectives on the Values in University Administration :: Reflection on Empiricism Through Critical Paradigm Christy, Nisa Novia Avien; Wu, Ming-Chang; Wibowo, Radna Andi; Dwiantari, Scorina
JURNAL ILMIAH EDUNOMIKA Vol. 9 No. 3 (2025): EDUNOMIKA
Publisher : ITB AAS Indonesia Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29040/jie.v9i3.17777

Abstract

The current educational environment is characterized by a high level of competitive pressure, which is the result of meritocratic policies and the multifaceted resources available. Universities are encouraged to use measurable, often instantaneous, accomplishments to demonstrate their self-accreditation. Consequently, the university administration strives to establish a mundane institutional reputation by focusing on quantitative but superficial metrics, including project grants, apparatus upgrades, and paper publication. In order to candidly envision the future of institutions and engage in a more in-depth discussion of the fundamental objectives of university education, there is a limited amount of reflection on the values of current university development. Consequently, this investigation employs literature analysis approaches to synthesize the subsequent issues: (1) the obstacles to empiricism and performanceism in university environments, (2) the reflection of administration values in contemporary universities, and (3) the proposed strategies for enhancing the fundamental values of university administration.
Co-Authors Christy, Nisa Novia Avien Dwiantari, Scorina Huang, Cian-Song Li, Qiao-Lin Lo, Diana Wang, Yuh-Tai Wibowo, Radna Andi