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Antioxidant Activity of Goat Milk Yogurt Casein on Dioxin Intoxicated Rat Liver Function Setianingrum, Ani; Padaga, Masdiana Chendrakasih
Veterinary Biomedical and Clinical Journal Vol. 1 No. 1 (2019)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (206.741 KB) | DOI: 10.21776/ub.VetBioClinJ.2019.001.01.4

Abstract

Dioxin is toxic contaminant which persistent in the environment. This compound bio-accumulate through food chain and generate adverse effect in human health. Oxidative stress due to dioxin exposure can interfere metabolism process and leads to the development of hepatotoxicity.The aim of this study was to asses the role of casein derived from goat milk yogurt in dioxin-intoxicated rat based on liver function parameters. Substances used were: 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) diluted in corn oil and casein from goat milk yogurt. The study included 24 Wistar rats divided into 6 groups: (1) control group, (2) placebo group which given casein 600 mg/kg BW, (3) TCDD group given with TCDD 100 ng/kg BW, (4) group P1 given casein 300 mg/kg BW and TCDD, (5) group P2 given casein 600 mg/kg BW and TCDD, (6) group P3 given casein 900 mg/kg BW and TCDD. The respective dose were given orally for 21 days. Blood serum was collected for transaminases (ALT, AST) and γ-glutamyl transferase (GGT) analysis. Based on serum transaminases activity, there were no significant change on AST and ALT level. Casein yogurt supplementation has significant effect on serum GGT level (p<0,05) and optimum dose was 600 mg/kg BW/day
Principles of Rural Tourism Development in Krisik Village, East Java: The Perspectives of Local Community Aulanni'am, Aulanni'am; Hariati, Anik Martinah; Sawitri, Manik Eirry; Padaga, Masdiana Chendrakasih; Wuragil, Dyah Kinasih; Hakim, Luchman
Journal of Indonesian Tourism and Development Studies Vol. 9 No. 2 (2021)
Publisher : Graduate School, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jitode.2021.009.02.05

Abstract

The research aimed to identify the local community perception in Krisik Village in Blitar Regency as a fundamental aspect of rural tourism planning and development. Three points were accepted as basic principles in rural tourism development, namely acceptance of rural tourism as an alternative to rural economic machine growth, promoting indigenous knowledge as a philosophy and value of rural tourism program implementation, and strengthening community-based tourism implementation in rural tourism programs Krisik Villages. Community involvement was a crucial issue in rural tourism planning and development.  In the limitation of human resources, the assistance of the university to support and increase human resources capacity in rural tourism development was important.Keywords: Ecotourism, community perception, tourism planning, tourism development