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The Effect of Carnitine on Reducing Triglyceride Levels Thoha, Thoha; Kusniawati, Kusniawati; Subaktio, Toto; Akbar, Roby Rahmadi; Putri, Prystia Riana
JURNAL INFO KESEHATAN Vol 22 No 4 (2024): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol22.Iss4.1657

Abstract

Carnitine is a crucial compound involved in the transport of long-chain fatty acids across mitochondrial membranes, playing an essential role in converting fat into energy. One of the most accessible ways to increase L-carnitine levels is through the consumption of red meat, which is a more affordable alternative compared to supplements. However, there is limited information on the optimal amount of red meat required to reduce blood triglyceride levels. This study aims to compare the effects of 50 mg and 100 mg of L-carnitine derived from red meat on blood triglyceride levels. The research utilized a quantitative approach with a quasi-experimental design. Participants included individuals aged 30-60 years with high triglyceride levels, who consumed beef did not take anti-cholesterol medications or had a history of diabetes. They also agreed to provide blood samples after an 8-9 hour fast. A simple random sampling method was used, with the first and odd-numbered participants assigned to the 100 mg group, and the second and even-numbered participants assigned to the 50 mg group. A total of 38 respondents were involved, with 19 in each group. The results indicated that the mean rank for the 100 mg carnitine group (17.32) was lower than that of the 50 mg group (21.68), though statistical analysis revealed no significant difference in triglyceride reduction between the two doses. The conclusion is the 50 mg carnitine group exhibited a higher increase in triglyceride levels compared to the 100 mg group. These findings suggest that a 12-day intervention with 100 mg of carnitine may prevent an increase in blood triglycerides, while 50 mg may not have the same effect.
Analisis determinan faktor yang memengaruhi self management pada klien dengan hipertensi Sari, Yunita; Sari, Kirana Candra; Putri, Prystia Riana
Holistik Jurnal Kesehatan Vol. 19 No. 9 (2025): Volume 19 Nomor 9
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/hjk.v19i9.1676

Abstract

Background: Hypertension is a condition in which both systolic and diastolic blood pressure exceed the normal range, as indicated by three measurements. Hypertension is a chronic non-communicable disease (NCD) requiring lifelong treatment, including risk factor management, activity management, nutrition/diet, and medication. Therefore, hypertension requires long-term treatment. Involving those closest to the patient, namely the family, is one strategy to assist in the management of hypertensive patients. Purpose: To analyze the determinants influencing self-management in clients with hypertension. Method: This descriptive correlational study used a cross-sectional approach. The population used in this study were hypertensive patients undergoing treatment at the Mandala Community Health Center. The diagnosis of hypertension was confirmed using secondary data from the Community Health Center. The sampling technique used was purposive sampling, and data collection was carried out using a questionnaire. The data were then analyzed using the chi-square test. Results: A p-value of 0.012 was obtained for the variables age, gender 0.01, income 0.017, and marital status 0.042. This indicates a relationship between the variables of age, gender, income, and marital status and hypertension self-management. Conclusion: There is a relationship between the variables of age, gender, income, and marital status and hypertension self-management (p-value <0.05). Suggestion: Educational programs are needed to improve self-management and increase confidence in patients' perceptions of hypertension susceptibility and severity.   Keywords: Adherence; Hypertension; Self-Management.   Pendahuluan: Hipertensi merupakan kondisi dimana tekanan sistol dan diastole melebihi normal yang diindikasi kandengan 3x pengukuran. Hipertensi merupakan salah satu penyakit tidak menular (PTM) dan bersifat kronis sehingga memerlukan pengobatan seumur hidup, baik dari segi pengendalian faktor risiko, kontrol aktivitas, nutrisi/diit, maupun pengobatannya. Oleh karena itu, penyakit hipertensi membutuhkan pengobatan jangka panjang. Pendekatan dengan orang terdekat, yaitu keluarga merupakan salah satu strategi untuk membantu tata laksana penanganan pasien hipertensi. Tujuan: Untuk menganalisis determinan faktor yang memengaruhi self management pada klien dengan hipertensi. Metode: Penelitian deskriptif korelasional dengan pendekatan cross sectional. Populasi yang digunakan pada penelitian ini adalah penderita hipertensi yang sedang menjalani pengobatan di Puskesmas Mandala. Penegakan diagnosa hipertensi dibuktikan dari data sekunder Puskesmas. Teknik pengambilan sampel menggunakan purposive sampling dan pengumpulan data menggunakan kuesioner, selanjutnya data di analisis melalui uji chi square. Hasil: Didapatkan p value 0.012 pada variabel umur, jenis kelamin 0.01, penghasilan 0.017, dan status pernikahan 0.042. Hal ini menunjukkan adanya hubungan antara variabel umur, jenis kelamin, penghasilan, dan status pernikahan terhadap self management hipertensi. Simpulan: Adanya hubungan antara variabel umur, jenis kelamin, penghasilan, dan status pernikahan terhadap self management hipertensi (p-value < 0.05). Saran: Perlu pengembangan program edukasi untuk meningkatkan self management dan meningkatkan keyakinan tentang persepsi kerentanan dan tingkat keparahan bagi pasien hipertensi.   Kata Kunci: Hipertensi; Kepatuhan; Self Management.