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The potency of bay leaves extract (Syzygiumpolyanthum) as anti-inflammation in Rattus norvegicus induced with Complete Freund’s Adjuvant Buana, Dwi Candra; Sudiana, I Ketut; Nugraha, Jusak
Jurnal Teknologi Laboratorium Vol 8 No 2 (2019): 2019 (2)
Publisher : POLTEKKES KEMENKES YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1954.413 KB) | DOI: 10.29238/teknolabjournal.v8i2.177

Abstract

The using of herbal plants in Indonesia as medicine based on traditional knowledge. One of the herbal plants that believed has medication effect is bay leaves (Syzygiumpolyanthum). Bay leaves contain a flavonoid that can prevent inflammation. The study aims to prove the potency of bay leaves extract to prevent the inflammation, which is indicated by decreasing the paw edema thickness in rat induced with Complete Freund's Adjuvant (CFA). This study used 25 animal models of male rat (Rattus norvegicus) strain Wistar that divided into five groups, one group for a normal group (no treatment), one group for positive control which was injected with CFA sub plantar and given treatment with Na CMC and three test groups which is got three different doses of bay leaves extract peroral and the doses were 100 mg/kg BW, 300 mg/kg BW, 400 mg/kg BW, and injected with CFA into the sub plantar. Bay leaves extract was given one hour per oral before injected with CFA. The measurement of paw edema was done at 24 hours after CFA injection. The result of this study showed that bay leaves extract gave the anti-inflammation effect to the rats which were injected with CFA. It is concluded that bay leaves extract containing flavonoids plays a role in inhibit cytokines proinflammatory synthesis.
Rumah Imun dan Ambulan Motor sebagai Upaya Pencegahan Stunting dan Sarana Kegawatdaruratan di Desa Pagung Kabupaten Kediri Sulisetyawati, Theresia Indah Budhy; Roestamadji, Retno Indrawati; Megasari, Ni Luh Ayu; Imannia, Ristya Sylva; Wardhani, Renita Gusti; Maulanasari, Ersa Afifah; Cheardi, Natallensi Deara; Buana, Dwi Candra
Jurnal ABDINUS : Jurnal Pengabdian Nusantara Vol 8 No 2 (2024): Volume 8 Nomor 2 Tahun 2024
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29407/ja.v8i2.23173

Abstract

This community service aims to improve the skills and knowledge of the surrounding community as well as first aid accommodation to health service facilities in the community of Pagung Village, Semen District, Kediri Regency, East Java. The implementation method of this community service is a field survey to identify stunting problems, making pocket books on emergencies and stunting, making motorbike ambulances (LANTOR) to facilitate access to health services, and counseling related to emergencies, balanced nutrition, and stunting. The results of this community service show that counseling and training related to first aid and emergencies can improve the knowledge and skills of the community in Pagung Village, in addition, the provision of "LANTOR" can facilitate and smooth community mobility to the nearest health service facilities.