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Duration of diabetes as an important risk factor of microalbuminuria in type 2 diabetes Indriani, Vitasari; Lestari, Tri; Dewantari, Vidya
Universa Medicina Vol 39, No 1 (2020)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (825.133 KB) | DOI: 10.18051/UnivMed.2020.v39.42-46

Abstract

BACKGROUNDMicroalbuminuria is the earliest evidence of diabetic nephropathy and a major predictor of end stage renal disease (ESRD). The objective of the study was to determine the influence of several risk factors on the presence of microalbuminuria in type 2 diabetics.METHODSThis observational cross-sectional study was done on 73 patients with type 2 diabetes, who attended the Prolanis program in Primary Health Care from May to November 2018. Detailed medical histories including duration of diabetes and relevant clinical examinations including fasting blood sugar (FBS), post-prandial blood sugar (PPBS), HbA1c, serum creatinine, blood urea and urinary microalbumin were recorded for each patient. A multiple regression analysis was used to analyze the data. The analysis was assessed at 5% level of significance.RESULTSMean age of study population was 51.89 ± 6.78 years with female preponderance (51.1%). Mean FBS, PPBS, HbA1c, duration of diabetes, systolic blood pressure, microalbuminuria and serum creatinine was 182.51 ± 74.63 mg/dL, 186.25 ± 26.72 mg/dL, 8.8 ± 1.83%, 9.37 ± 5.96 years, 118.44 ± 4.13 mmHg, 30.32 ± 3.2 mg/day and 1.33 ± 0.64 mg/dL respectively. Duration of diabetes and HbA1c were positively correlated with microalbuminuria (â=0.052; Beta =0.367; p<0.001 and â=0.058; Beta=0.363; p<0.001) respectively.CONCLUSIONSDuration of diabetes was the most important risk factor of microalbuminuria in type 2 diabetes patients. Therefore microalbuminuria can predict diabetic nephropathy earlier, as a warning to prevent further worsening of diabetic complications.
Korelasi Antara Lingkar Kepala Lahir Dengan Tumbuh Kembang Anak Di Desa Rempoah Banyumas Salsabila, Sabrina Dhia; Santosa, Qodri; Fatchurohmah, Wiwiek; Hapsari, Ariadne Tiara; Indriani, Vitasari
Window of Health : Jurnal Kesehatan Vol 5 No 01 (January 2022)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33368/woh.v0i0.674

Abstract

The golden period of children’s growth occurred in the first 1000 days and every disruption in this period would damage the number of cells and myelination that could not be achieved in the next period. Head circumference (HC) at birth was correlated with brain size to measure the brain’s growth and development. This study aimed to find the correlation between HC at birth and children’s growth and development. The research method used was cross-sectional. A total sample of 233 children at 6-60 months old in Posyandu Bina Kasih I-XI Rempoah Village, Baturaden District, was taken using total sampling. Research data used secondary data from previous study and were analyzed by Eta and spearman correlation tests. Results show 180 children who have normal nutritional status and 221 children with development based on their age. Median HC at birth value is 33 cm belongs in the normal category. Spearman test shows HC at birth is not correlated with nutritional status (p=0.412). Eta test shows HC at birth was statiscally significant correlated with development based on KIA book albeit with a very weak level of correlation(F calculated > F table; ETA=0.196). In conclusion, Head circumference at birth is correlated with development based on the KIA book, but does not correlated with nutritional status and head circumference.
HUBUNGAN BERAT BADAN LAHIR DENGAN STATUS GIZI DAN PERKEMBANGAN ANAK USIA 6 – 60 BULAN Andreanetta, Prisca Tiffany; Santosa, Qodri; Indriani, Vitasari; Arifah, Kurniawati; Fatchurohmah, Wiwiek
E-Jurnal Medika Udayana Vol 11 No 9 (2022): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2022.V11.i9.P07

Abstract

Periode emas kehidupan akan menentukan tumbuh kembang anak di masa yang akan datang. Berat badan lahir (BBL) merupakan salah satu faktor yang memengaruhi tumbuh kembang anak. Tujuan penelitian ini untuk mengetahui korelasi antara BBL dengan status gizi dan perkembangan anak usia 6 – 60 bulan. Penelitian ini menggunakan analisis observasional dengan pendekatan cross sectional study. Subjek penelitian yaitu anak – anak balita di Posyandu Bina Kasih I – XI Desa Rempoah pada bulan Oktober – November 2018 dengan menggunakan data sekunder. Uji korelasi BBL dengan status gizi menggunakan analisis Spearman dan korelasi BBL dengan perkembangan menggunakan uji Eta. Sebagian besar subjek penelitian memiliki status gizi normal (74%) dan perkembangan sesuai buku KIA (94,1%). Hasil korelasi bermakna dan signifikan secara statistik antara BBL dengan status gizi (p=0,042) dan BBL dengan perkembangan berdasar buku KIA (F=96,25). Kesimpulan penelitian ini yaitu terdapat korelasi antara BBL dengan status gizi dan perkembangan berdasar buku KIA. Hasil penelitian ini diharapkan dapat menjadi acuan tenaga medis dalam memberikan informasi kepada ibu hamil mengenai gizi salama masa hamilnya.
Platelet-to-Lymphocyte Ratio as Coagulopathy Predictor in COVID-19 Patients at Margono Soekarjo Hospital Siswandari, Wahyu; Saksana, Rachmad Aji; Indriani, Vitasari; Fuadi, Muhammad Robiul
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 31 No. 1 (2024)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v31i1.2268

Abstract

Coronavirus Disease 2019 (COVID-19) is a disease possibly attacking various organs and systems of the body including the coagulation system causing coagulopathy. Various laboratory biomarkers have been developed to detect coagulopathy. This research aimed to determine the correlation and ability of Platelet-to-Lymphocyte Ratio (PLR) in predicting coagulopathy when compared to D-dimer. A cross-sectional research was conducted on 1580 data of COVID-19 patients at Margono Soekarjo Hospital. The research data were then analyzed using Spearman’s correlation test to figure out the correlation between PLR and D-dimer. This research was also intended to find the PLR Cut-Off Value (COV), Odds Ratio (OR), Area Under Receiver Operating Characteristic (AUROC), and diagnostic value. Platelet-to-lymphocyte ratio value had a significant correlation with D-dimer levels (r=0.260, p=0.000). The COV of PLR was 176.61 with the OR of 2.7 (2.2-3.3 95%CI), AUROC of 0.638, sensitivity of 62%, and specificity of 62%. PLR can be used as a screening biomarker to predict the occurrence of coagulopathy in COVID-19 patients.