Topographical heterogeneity in water distribution networks frequently causes pressure imbalance, hydraulic inefficiency, and elevated energy consumption, particularly in regions with significant elevation gradients. This study aims to develop and validate a dynamic Internet of Things (IoT)-based pressure control model within a cyber–physical system framework for energy-efficient water distribution under varied geographical conditions. The primary contribution of this work lies in the separation of strategic and tactical control layers, where a Digital Twin based on EPANET dynamically generates optimal pressure setpoints, while distributed proportional–integral–derivative controllers execute real-time valve regulation at the network edge. The research adopts a Design Science Research methodology to design, implement, and evaluate a four-layer architecture consisting of physical sensing and actuation, long-range communication, tactical control, and strategic simulation layers. Validation is conducted using EPANET-based simulations across three control scenarios: a baseline condition without dynamic control, a static rule-based valve control scenario, and the proposed dynamic IoT–PID control scenario. The experimental procedure involves comparative analysis using control performance metrics including overshoot, settling time, steady-state error, and root mean square error. Simulation results demonstrate that the baseline configuration suffers from severe pressure imbalance and hydraulic backflow, while static rule-based control partially mitigates inefficiencies but fails to adapt to demand variability. In contrast, the proposed dynamic IoT–PID approach achieves precise pressure regulation with overshoot below 2% and tracking error maintained under 0.5 meters across all evaluated scenarios. These findings confirm that integrating a Digital Twin with real-time PID control significantly improves pressure stability and operational efficiency. The proposed architecture offers practical implications for smart water infrastructure in geographically diverse regions, providing a scalable foundation for adaptive pressure management, energy optimization, and future digital-twin-driven water distribution systems.