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Hubungan Kadar Vitamin D3 Dengan Derajat Kepositifan BTA Pada Penderita Tuberkulosis Paru Kuncara, Rachmad Bayu; Istiqomah, Anisa; Hartono, Rodhi; Priyatno, Djoko
Jurnal Analis Kesehatan Vol. 12 No. 2 (2023): Jurnal Analis Kesehatan
Publisher : Department of Health Analyst, Politeknik Kesehatan, Kementerian Kesehatan Tanjungkarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jak.v12i2.3925

Abstract

Tuberkulosis paru adalah penyakit menular yang disebabkan bakteri Mycobacterium tuberculosis (MTB). Pemeriksaan mikroskopis Bakteri Tahan Asam (BTA) merupakan pemeriksaan yang penting untuk membantu diagnosis tuberculosis paru. Penderita tuberculosis paru dapat mengalami peningkatan jumlah BTA apabila mengalami defisiensi vitamin D. Vitamin D dapat menghambat multiplikasi MTB dalam makrofag dengan induksi peptida anti mikroba. Penelitian ini bertujuan untuk mengetahui hubungan kadar vitamin D3 dengan derajat kepositifan bakteri tahan asam pada penderita tuberkulosis paru. Jenis penelitian ini adalah observasional analitik dengan desain cross sectional. Sampel penelitian sebanyak 30 responden diambil dari Puskesmas Bangetayu, Puskesmas Tlogosari Wetan, dan Puskesmas Kedungmundu di Kota Semarang. Sampel tersebut diperiksa BTA secara mikroskopis dan pemeriksaan vitamin D3 dilakukan dengan metode Enzym Linked Immunosorbent Assay (ELISA). Hasil pemeriksaan BTA menunjukan sebanyak 12 (40,0%) penderita dengan hasil scanty, sebanyak 7 (23,3%) penderita positif 1, sebanyak 7 (23,3%) penderita positif 2 dan 4 (13,4%) penderita positif 3. Hasil pemeriksaan vitamin D menunjukan sebanyak 23 (76,7%) penderita dengan status defisiensi, 5 (76,7%) penderita dengan status insufisiensi dan 2 (6,7%) penderita dengan status sufisiensi. Data tersebut dianalisa secara statiskik menggunakan uji Spearman dengan hasil p-Value = 0,023 (p< 0,05) sehingga dapat disimpulkan terdapat hubungan kadar vitamin D3 dengan derajat kepositifan BTA pada penderita tuberculosis paru.
The impact of financial literacy, campus environment, and lifestyle the consumptive financial management students Istiqomah, Anisa; Nugraheni, Krisnawati Setyaningrum
Jurnal Mantik Vol. 8 No. 2 (2024): August: Manajemen, Teknologi Informatika dan Komunikasi (Mantik)
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/mantik.v8i2.5450

Abstract

This research aims to determine the influence of financial literacy, campus environment, and lifestyle on the consumer financial management of online shopping among STIEPARI Semarang students. This is a quantitative research study. The population and sample in this study are STIEPARI Semarang students, with a total of 95 respondents. This study uses multiple linear regression analysis to analyze and test the hypotheses. The results of this study show that the first variable, The Effect of Financial Literacy, has a positive and significant impact on Consumer Financial Management of Online Shopping among STIEPARI Semarang Students; the second variable, Campus Environment, has a positive and significant effect on Consumer Financial Management of Online Shopping among STIEPARI Semarang Students; the third variable, Lifestyle, has a positive and significant influence on Consumer Financial Management of Online Shopping among STIEPARI Semarang Students; and the fourth variable, The Influence of Financial Literacy, Campus Environment, and Lifestyle, together have a positive and significant impact on Consumer Financial Management of Online Shopping among STIEPARI Semarang Students
Organizational Citizenship Behavior Employment Gas Station in Indonesia (Literature Review) Istiqomah, Anisa; Aminalul , Safira; Rizana, Dani
EKONOMI DAN BISNIS DIGITAL Vol 3 No 3 (2024): JURNAL EKONOMI DAN BISNIS DIGITAL
Publisher : SMARTINDO

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58765/ekobil.v3i3.243

Abstract

Organizational citizenship behavior (OCB) is very important for Public Fuel Filling Station (SPBU) employees because of the increasing demand for fuel. Even causing long queues at gas stations. This often happens in the morning and evening. According to data from the Central Statistics Agency (BPS), the transportation and storage sector shows stable growth. In this context, OCB is becoming increasingly important for gas station employees to maintain competitiveness and improve service quality at gas stations. Gas stations operate in a highly competitive environment, where customer satisfaction is the key to success. OCB can increase gas station customer satisfaction. Staff who are agile in helping customers and supporting co-workers can reduce wait times and improve the customer experience. This implies higher customer loyalty, which is very important in a competitive industry. Employees who demonstrate OCB can improve the customer experience by providing better and more responsive service. The results of the analysis state that Organizational Citizenship Behavior (OCB) plays a crucial role in increasing customer satisfaction, organizational performance and the competitiveness of gas stations in Indonesia. To encourage OCB, HR management needs to create a supportive environment with effective reward strategies, good leadership and appropriate training programs. However, challenges such as high employee rotation and limited resources remain obstacles that must be overcome.
GBE1 Inhibition: Alternative Therapy for Lung Cancer by Altering Glucose Metabolism Istiqomah, Anisa; Ariani, Yulia; Ari Pujianto, Dwi
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i3.57677

Abstract

Lung cancer represents a neoplastic malignancy within pulmonary tissue and is associated with the highest mortality rate attributed to cancer globally. Non-Small Cell Lung Cancer (NSCLC) constitutes the predominant category of lung cancer, accounting for approximately 80-85% of all diagnosed cases, with adenocarcinoma subtyping comprising nearly 40% of NSCLC instances. Despite advancements in surgical techniques and diverse therapeutic modalities, the five-year survival rate remains below 20%, necessitating ongoing research endeavors aimed at the enhancement of lung cancer treatment paradigms. This review investigates the intricate interplay between Glycogen Branching Enzyme 1 (GBE1) and metabolic reprogramming, as well as its interaction with hypoxic environments and subsequent effects on the phenotypic characteristics of lung cancer cells. Hypoxic conditions frequently manifest in solid tumors, including lung cancer, eliciting adaptive responses such as the activation of Hypoxia-Inducible Factor-1 alpha (HIF1α), which subsequently initiates angiogenesis, induces metabolic alterations, and contributes to therapeutic resistance. Glycogen Branching Enzyme 1 (GBE1) serves as a critical enzyme involved in the synthesis of glycogen branching structures. In the context of lung adenocarcinoma (LUAD), GBE1 operates within the downstream signaling cascade of the Hypoxia-Inducible Factor-1 (HIF1) pathway. This review aspires to furnish novel insights into the pathogenesis of lung cancer and to assess the strategic targeting of the HIF1α/GBE1/NF-κB/FBP1 axis as a promising therapeutic approach for LUAD.
Kreativitas Guru Dalam Meningkatkan Motivasi Belajar Peserta Didik Kelas 6 SDN 1 Lungkuh Layang Ambya, Rizky; Dewi, Lisna; Agustin, Efawati; Hasanah, Iswatun; Istiqomah, Anisa; Nurhapid, Ahmad; Eka Putri, Febbyanti Agutina; Amal, Mukhlishul; Puji Astuti, Wakhidah; Rusliani, Waode Gusti; Saudah, Saudah
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 5 No. 1 (2024): Jurnal Pengabdian kepada Masyarakat Nusantara (JPkMN)
Publisher : Lembaga Dongan Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55338/jpkmn.v5i1.2566

Abstract

Belajar merupakan suatu proses yang ditandai dengan adanya perubahan dalam diri seseorang baik pengetahuannya, pemahamannya, sikap dan tingkah lakunya maupun keterampilannya. Berdasarkan observasi yang dilakukan, bahwa yang melatarbelakangi minimnya semangat para siswa dalam belajar karena terdapat berbagai masalah khususnya masalah keluarga, terkendala ekonomi juga fasilitas belajar yang kurang memadai, seperti halnya yang terjadi pada siswa di SDN 1 Lungkuh Layang yaitu tempat dilaksanakannya PKM. Metode yang digunakan dalam pengabdian ini yaitu metode ceramah, metode tanya jawab dan metode diskusi kelompok dengan model pembelajaran Problem Based Learning (PBL). Pengabdian ini bertujuan untuk meningkatkan minat dan motivasi belajar siswa di SDN 1 Lungkuh Layang dalam menempuh pendidikan. Pengabdian ini penting mengingat minat dan motivasi belajar adalah hal yang perlu dimiliki oleh siswa untuk menyelesaikan studinya. Hasil dari pengabdian ini menunjukan bahwa, siswa lebih merasa bersemangat untuk mengikuti pembelajaran jika metode pembelajaran yang digunakan mampu membawa mereka untuk aktif mengikuti pembelajaran tersebut. Melalui model pembelajaran PBL para siswa lebih terampil dalam berpikir kritis ketika belajar, selain itu siswa lebih mampu bekerja sama menyelesaikan suatu permasalahan.
Pengaruh Penggunaan Media Elektronik terhadap Motivasi Belajar Santri di Pondok Pesantren Hidayatul Mubtadiin Tahun Pelajaran 2025/2026: Penelitian Istiqomah, Anisa; Rohmiyati, Ummi; Istiqomah, Dedeh; Pujianti, Etika
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 3 No. 4 (2025): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 3 Nomor 4 (April 2025
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v3i4.495

Abstract

This research aims to analyze the influence of the use of electronic media at the Hidayatul Mubtadiin Islamic boarding school on the learning motivation of students at the Hidayatul Mubtadiin Islamic boarding school for the 2025/2026 academic year. This research uses descriptive qualitative methods with data collection techniques through interviews, observation and documentation (Miles & Hubermen 1994). The results of this research show how much influence the use of electronic media has on the motivation of students at the Hidayatul Mubtadiin Islamic boarding school. This has a big influence on the learning motivation of the students, so many things have to be improved so that the students will be able to use this media in a positive way
RISK EFFECT ON CONTRIBUTION OF PARTICIPANTS IN SHARIA INSURANCE INDONESIA Istiqomah, Anisa; Gati, Vidia
Jurnal Ekonomi dan Bisnis Islam (Journal of Islamic Economics and Business) Vol. 6 No. 1 (2020): JANUARY-JUNE 2020
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jebis.v6i1.18254

Abstract

This study aims to prove the effect of operational costs, investment returns, claims and minimum risk-based tabarru' funds partially and simultaneously on the contribution of Islamic general insurance in Indonesia 2015-2018. This study uses a quantitative approach with secondary data in the form of publication of annual Islamic financial statements and sample selection using a purposive sampling technique. The amount of data is 11 companies with observations over four years to obtain 44 observational data used as samples in this study. The technique used is regression analysis using a fixed effect model (FEM) panel data. The results illustrate that partially, minimum variable costs based on operational risk, claims, and tabarru' funds have a significant positive effect on participant contributions. Thus proving that the higher the minimum operational costs based on claims, and tabarru' 'will influence the determination of participant contributions. As for investment returns, it has no effect on determining participant contributions because funds can be allocated to increase assets. Simultaneous statistical test results from operational costs, investment returns, claims, minimum risk-based funds are influenced by participant contributions. This research suggestion should be that Islamic general insurance companies can conduct regular audits on the use of operational costs to make it more efficient so that the allocation of contribution costs can be directed towards the growth of assets or minimum risk-based tabarru' funds of the company.Keywords: Contribution, Islamic insurance, Participant, Risk-based, Tabarru' funds