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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Analis Kesehatan Jurnal Mantik Jurnal Ekonomi dan Bisnis Digital
Istiqomah, Anisa
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Humanities Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Social Sciences Other

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Hubungan Kadar Vitamin D3 Dengan Derajat Kepositifan BTA Pada Penderita Tuberkulosis Paru Kuncara, Rachmad Bayu; Istiqomah, Anisa; Hartono, Rodhi; Priyatno, Djoko
Jurnal Analis Kesehatan Vol. 12 No. 2 (2023): Jurnal Analis Kesehatan
Publisher : Department of Health Analyst, Politeknik Kesehatan, Kementerian Kesehatan Tanjungkarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jak.v12i2.3925

Abstract

Tuberkulosis paru adalah penyakit menular yang disebabkan bakteri Mycobacterium tuberculosis (MTB). Pemeriksaan mikroskopis Bakteri Tahan Asam (BTA) merupakan pemeriksaan yang penting untuk membantu diagnosis tuberculosis paru. Penderita tuberculosis paru dapat mengalami peningkatan jumlah BTA apabila mengalami defisiensi vitamin D. Vitamin D dapat menghambat multiplikasi MTB dalam makrofag dengan induksi peptida anti mikroba. Penelitian ini bertujuan untuk mengetahui hubungan kadar vitamin D3 dengan derajat kepositifan bakteri tahan asam pada penderita tuberkulosis paru. Jenis penelitian ini adalah observasional analitik dengan desain cross sectional. Sampel penelitian sebanyak 30 responden diambil dari Puskesmas Bangetayu, Puskesmas Tlogosari Wetan, dan Puskesmas Kedungmundu di Kota Semarang. Sampel tersebut diperiksa BTA secara mikroskopis dan pemeriksaan vitamin D3 dilakukan dengan metode Enzym Linked Immunosorbent Assay (ELISA). Hasil pemeriksaan BTA menunjukan sebanyak 12 (40,0%) penderita dengan hasil scanty, sebanyak 7 (23,3%) penderita positif 1, sebanyak 7 (23,3%) penderita positif 2 dan 4 (13,4%) penderita positif 3. Hasil pemeriksaan vitamin D menunjukan sebanyak 23 (76,7%) penderita dengan status defisiensi, 5 (76,7%) penderita dengan status insufisiensi dan 2 (6,7%) penderita dengan status sufisiensi. Data tersebut dianalisa secara statiskik menggunakan uji Spearman dengan hasil p-Value = 0,023 (p< 0,05) sehingga dapat disimpulkan terdapat hubungan kadar vitamin D3 dengan derajat kepositifan BTA pada penderita tuberculosis paru.
The impact of financial literacy, campus environment, and lifestyle the consumptive financial management students Istiqomah, Anisa; Nugraheni, Krisnawati Setyaningrum
Jurnal Mantik Vol. 8 No. 2 (2024): August: Manajemen, Teknologi Informatika dan Komunikasi (Mantik)
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/mantik.v8i2.5450

Abstract

This research aims to determine the influence of financial literacy, campus environment, and lifestyle on the consumer financial management of online shopping among STIEPARI Semarang students. This is a quantitative research study. The population and sample in this study are STIEPARI Semarang students, with a total of 95 respondents. This study uses multiple linear regression analysis to analyze and test the hypotheses. The results of this study show that the first variable, The Effect of Financial Literacy, has a positive and significant impact on Consumer Financial Management of Online Shopping among STIEPARI Semarang Students; the second variable, Campus Environment, has a positive and significant effect on Consumer Financial Management of Online Shopping among STIEPARI Semarang Students; the third variable, Lifestyle, has a positive and significant influence on Consumer Financial Management of Online Shopping among STIEPARI Semarang Students; and the fourth variable, The Influence of Financial Literacy, Campus Environment, and Lifestyle, together have a positive and significant impact on Consumer Financial Management of Online Shopping among STIEPARI Semarang Students
Organizational Citizenship Behavior Employment Gas Station in Indonesia (Literature Review) Istiqomah, Anisa; Aminalul , Safira; Rizana, Dani
EKONOMI DAN BISNIS DIGITAL Vol 3 No 3 (2024): JURNAL EKONOMI DAN BISNIS DIGITAL
Publisher : SMARTINDO

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58765/ekobil.v3i3.243

Abstract

Organizational citizenship behavior (OCB) is very important for Public Fuel Filling Station (SPBU) employees because of the increasing demand for fuel. Even causing long queues at gas stations. This often happens in the morning and evening. According to data from the Central Statistics Agency (BPS), the transportation and storage sector shows stable growth. In this context, OCB is becoming increasingly important for gas station employees to maintain competitiveness and improve service quality at gas stations. Gas stations operate in a highly competitive environment, where customer satisfaction is the key to success. OCB can increase gas station customer satisfaction. Staff who are agile in helping customers and supporting co-workers can reduce wait times and improve the customer experience. This implies higher customer loyalty, which is very important in a competitive industry. Employees who demonstrate OCB can improve the customer experience by providing better and more responsive service. The results of the analysis state that Organizational Citizenship Behavior (OCB) plays a crucial role in increasing customer satisfaction, organizational performance and the competitiveness of gas stations in Indonesia. To encourage OCB, HR management needs to create a supportive environment with effective reward strategies, good leadership and appropriate training programs. However, challenges such as high employee rotation and limited resources remain obstacles that must be overcome.
GBE1 Inhibition: Alternative Therapy for Lung Cancer by Altering Glucose Metabolism Istiqomah, Anisa; Ariani, Yulia; Ari Pujianto, Dwi
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i3.57677

Abstract

Lung cancer represents a neoplastic malignancy within pulmonary tissue and is associated with the highest mortality rate attributed to cancer globally. Non-Small Cell Lung Cancer (NSCLC) constitutes the predominant category of lung cancer, accounting for approximately 80-85% of all diagnosed cases, with adenocarcinoma subtyping comprising nearly 40% of NSCLC instances. Despite advancements in surgical techniques and diverse therapeutic modalities, the five-year survival rate remains below 20%, necessitating ongoing research endeavors aimed at the enhancement of lung cancer treatment paradigms. This review investigates the intricate interplay between Glycogen Branching Enzyme 1 (GBE1) and metabolic reprogramming, as well as its interaction with hypoxic environments and subsequent effects on the phenotypic characteristics of lung cancer cells. Hypoxic conditions frequently manifest in solid tumors, including lung cancer, eliciting adaptive responses such as the activation of Hypoxia-Inducible Factor-1 alpha (HIF1α), which subsequently initiates angiogenesis, induces metabolic alterations, and contributes to therapeutic resistance. Glycogen Branching Enzyme 1 (GBE1) serves as a critical enzyme involved in the synthesis of glycogen branching structures. In the context of lung adenocarcinoma (LUAD), GBE1 operates within the downstream signaling cascade of the Hypoxia-Inducible Factor-1 (HIF1) pathway. This review aspires to furnish novel insights into the pathogenesis of lung cancer and to assess the strategic targeting of the HIF1α/GBE1/NF-κB/FBP1 axis as a promising therapeutic approach for LUAD.
Co-Authors Aminalul , Safira Ari Pujianto, Dwi Dani Rizana Djoko Priyatno, Djoko Kuncara, Rachmad Bayu Nugraheni, Krisnawati Setyaningrum Rodhi Hartono Yulia Ariani