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All Journal Journal of Indonesian Dental Association Cakradonya Dental Journal
Alibasyah, Zulfan M
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Dentistry Public Health

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AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 70% DAUN BIDURI (Calotropis gigantea) TERHADAP Aggregatibacter actinomycetemcomitans ATCC 29523 Alibasyah, Zulfan M; Ningsih, Diana Setya; Sinda, Maya Putri
Cakradonya Dental Journal Vol 12, No 2 (2020): Agustus 2020
Publisher : FKG Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/cdj.v12i2.17831

Abstract

Aggregatibacter actinomycetemcomitans ATCC 29523 merupakan bakteri biakan murni yang bersifat anaerob fakultatif Gram-negatif. Bakteri ini dominan pada periodontitis agresif lokalisata dan berperan penting dalam patogenesisnya. Daun biduri (Calotropis gigantea) mengandung flavonoid, fenol, tanin, saponin, terpenoid, dan alkaloid yang merupakan senyawa antibakteri. Metode maserasi dilakukan untuk pembuatan ekstrak Calotropis gigantea dengan menggunakan etanol 70% sebagai bahan pelarut. Penelitian ini termasuk eksperimental laboratoris menggunakan metode difusi sumuran dalam pengujian aktivitas antibakteri ekstrak etanol 70% daun Calotropis gigantea terhadap Aggregatibacter actinomycetemcomitans ATCC 29523 pada konsentrasi 5%, 10%, 15%, 20%, 25%, dan 30%. Setiap konsentrasi menunjukkan hasil zona hambat sebesar 3,3 mm, 9,6 mm, 11 mm, 12,7 mm, 14,4 mm, dan 16,6 mm. Didapatkan hasil zona hambat yang berbeda pada berbagai konsentrasi, dan hasil hambatan semakin besar pada konsentrasi yang semakin tinggi. Analisis dengan uji one way Anova menunjukkan nilai signifikansi p0,05 yang menyatakan semua hasil penelitian ini memiliki perbedaan bermakna. Berarti bahwa ekstrak etanol 70% daun biduri (Calotropis gigantea) dalam berbagai konsentrasi di atas dapat menghambat pertumbuhan Aggregatibacter actinomycetemcomitans ATCC 29523.
Relationship between Smoking Habit and Nicotine Level with Salivary Flow Rate and pH nati, Sun; Furqan, Al; Ismi, Nuzulul; Alibasyah, Zulfan M; Saputri, Dewi
Journal of Indonesian Dental Association Vol 8 No 2 (2025): October
Publisher : Indonesian Dental Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32793/jida.v8i2.1445

Abstract

Introduction: High nicotine levels from smoking can affect salivary composition and function, which in turn can contribute to oral health problems such as dental caries and periodontal disease. Objective: The purpose of this study was to investigate the relationship between smoking habits and nicotine levels with salivary flow rate and pH in students of the Faculty of Engineering, Universitas Syiah Kuala. Methods: This study was a cross-sectional research design and examined 100 students of the Faculty of Engineering, Syiah Kuala University. Saliva collected by the spitting method. Results: The results of research on students of the Faculty of Engineering, Universitas Syiah Kuala, show that smoking habits and nicotine levels have a significant on the flow rate and pH of saliva in student smokers. Conclusion: There is a significant relationship between smoking habits and nicotine levels in cigarettes, with flow rate and salivary pH in smoking students. The habit of smoking affects the decrease in salivary flow rate and changes in salivary pH, with a moderate to strong strength of relationship.
Co-Authors Al Furqan, Al Diana Setya Ningsih, Diana Setya Ismi, Nuzulul nati, Sun Saputri, Dewi Sinda, Maya Putri