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Phytochemical Screening of Active Secondary Metabolites and Antibacterial Activity Kaffir Lime Leaf (Citrus hystrix) and Tumeric Leaf (Curcuma longa Linn.) Against Escherichia coli Suryani, Novia; Munawar, Faradillah; Hajaroh, Siti
ALKIMIA Vol 5 No 2 (2021): ALKIMIA
Publisher : SCIENCE AND TECHNOLOGY FACULTY OF UNIVERSITAS ISLAM NEGERI RADEN FATAH PALEMBANG

This study aims to determine the content of active compounds of secondary metabolites and antibacterial activity of secondary metabolites from a maceration of turmeric leaf (Curcuma longa Linn.) and kaffir lime leaf (Citrus hystrix) against Escherichia coli (E. coli). Each sample of kaffir lime leaf and turmeric leaf was extracted by maceration method using 96% ethanol solvent for 3 x 24 hours and the solvent was changed every 1 x 24 hours, then the filtered filtrate was thickened using a rotary evaporator. The phytochemical screening test was carried out by qualitative method using chemical reagents. The antibacterial activity test of the extract of the combination of turmeric leaves (Curcuma longa Linn.) and kaffir lime leaves (Citrus hystrix) used the Punch Hole Diffusion method with various concentrations of 20%, 40%, 60%, 80%, and 100%. The results showed that the combined extract of turmeric leaf (Curcuma longa Linn.) and kaffir lime leaf (Citrus hystrix) contained secondary metabolites in the form of flavonoids, alkaloids, steroids, tannins, and saponins. The optimum zone of inhibition to inhibit the growth of E. coli produced was 9.73 ± 0.78 mm. Overall, it can be concluded that the combined extract of turmeric leaf (Curcuma longa Linn.) and kaffir lime leaf (Citrus hystrix) has potential as an alternative to antibacterial active compounds.

Toxicity Test of Elo (Ficus Racemosa L.) Leaf Extracts and Fractions Using Brine Shrimp Lethality Test Methods Suryani, Novia; Gustiana, Serli
Al-Kimia Vol 11 No 2 (2023): DESEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v11i2.40821

This study aims to determine the toxicity ability of the Ficus racemosa L. plant, known as the elo plant, which has been widely applied as an alternative medicine for natural ingredients. The use of natural ingredients as drug candidates is one option to increase the value of natural ingredients and become biodiversity in Indonesia. The research method used is the maceration method used to obtain leaf extract. Furthermore, the extract obtained was partitioned using n-hexane, ethyl acetate, and chloroform solvents to obtain the leaf fraction. Qualitative tests were carried out to determine the secondary metabolite compounds. Meanwhile, the toxicity ability of elo plant extract and leaf fraction was tested using the Brine Shrimp Lethality Test (BSLT) as an initial toxicity screening with Artemia salina Leach. Based on the results, revealed the extract and fraction of the leaves contained secondary metabolites in the form of flavonoids, alkaloids, and saponins. Toxicity test obtained LC50 value of leaf extract of 91.76 ppm; leaf n-hexane fraction of 220.47 ppm; leaf ethyl acetate fraction of 249.13 ppm; and leaf chloroform fraction of 338.16 ppm. Based on the LC50 value, it reveals that the leaf extract and leaf fraction of the elo plant perform toxic potency.

Pengaruh Dana Pihak Ketiga (DPK) Dan Modal Terhadap Profitabilitas (Roa) Bank Syariah Mandiri Febriani, Dina; Suryani, Novia
Emanasi : Jurnal Ilmu Keislaman dan Sosial Vol 2 No 2 (2019): Jurnal Emanasi Volume 2 Edisi 2 Tahun 2019
Publisher : Asosiasi Dosen Peneliti Ilmu Keislaman dan Sosial

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Penelitian ini bertujuan untuk menganalisis pengaruh Dana Pihak Ketiga (DPK) dan modal terhadap pertumbuhan profitabilitas BNI Syariah tahun 2015-2019. Variabel yang digunakan dalam penelitian ini adalah variabel terikat yaitu profitabilitas yang diukur dengan Return On Asset (ROA), dan variabel independen yaitu Dana Pihak Ketiga (DPK) dan modal. Metode analisis yang digunakan adalah regresi berganda. Data yang digunakan dalam penelitian ini adalah data runtun waktu (time series) yang berasal dari laporan keuangan bulanan BNI Syariah tahun 2015 sampai dengan tahun 2019. Hasil penelitian menunjukkan bahwa variabel berpengaruh signifikan terhadap profitabilitas yang diukur dengan ROA adalah Dana Pihak Ketiga (DPK). Sedangkan modal tidak berpengaruh positif secara signifikan terhadap profitabilitas (ROA).

PROFIL FITOKIMIA DAN ANALISIS TOKSISITAS Ficus racemosa L. MENGGUNAKAN METODE BRINE SHRIMP (Artemia salina) LETHALITY TEST Suryani, Novia
ALOTROP Vol. 7 No. 2 (2023): Alotrop 2023
Publisher : University of Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/alo.v7i2.30801

[Phytochemical Profile and Toxicity Analysis of Figs (Ficus racemosa L.) Using Shrimp (Artemia salina) Brine Method Lethality Test] A traditional plant, Ficus racemosa L., known as the ara plant in West Nusa Tenggara, is potentially beneficial as a drug candidate, which is one option to develop the biodiversity of natural ingredients in Indonesia. The extract was produced by maceration method with ethanol 96% solvent. Furthermore, they partitioned using various solvents, n-hexane, ethyl acetate, and chloroform. The presence or absence of secondary metabolite is determined by the phytochemical screening test. Meanwhile, the Brine Shrimp Lethality Test (BSLT) is a toxicity screening to determine the LC50 of extract and their partition with various concentrations used were 50, 100, 250, 500, and 1000 ppm. The metabolite secondary flavonoids, alkaloids, and saponins are confirmed. The analysis showed that LC50 of extract was 218,34 ppm; n-hexane fraction was 413,57 ppm; ethyl acetate fraction was 309.51 ppm; and chloroform fraction was 314.60 ppm; all had toxic potential.

Physico-chemical characteristics of Figs Herbal Tea (Ficus racemosa L.) as a functional antidiabetic drink Dewi, Yuli Kusuma; Suryani, Novia
Journal of Natural Sciences and Mathematics Research Vol. 10 No. 2 (2024): December
Publisher : Faculty of Science and Technology, Universitas Islam Negeri Walisongo Semarang

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(Ficus racemosa L.) contain secondary metabolite compounds such as flavonoids, saponins, alkaloids, steroids, and tannins that have potential as a source of antioxidants. This study aims to determine the drying temperature variations on physicochemical characteristics of figs as an antidiabetic functional drink. The research methods begin by drying figs at various temperature (50°C, 60°C, and 70°C). The phytochemical test was followed by qualitative color change. The moisture content measurement was done using the thermogravimetric method. Then, the FTIR instrument identified the functional groups of organic compounds. Phytochemical analysis revealed the presence of flavonoids and tannins in all tea samples, regardless of drying temperature. FTIR spectroscopy confirmed the presence of phenolic compounds, characterized by O-H, Csp, and C=O enol groups. The pH of the tea at 50°C, 60°C, and 70°C, was 6.13; 5.64; and 5.59, the acidity of the pH obtained was indicated by the presence of phenolic compounds in all samples. The tea's moisture content was found to be within the Indonesian National Standard (<8%) at 60°C and 70°C, were 5.50% and 4.10%. Thus, fig tea, dried at 60°C or 70°C, can be developed as a functional antidiabetic drink.

Formulasi dan Evaluasi Sediaan Lotion Pencegah Photo Aging Ekstrak Etanol Buah Ficus racemosa L. Suryani, Novia; Ernita, Nevi; Hidayanti, Baiq Rauhil; Damalianti, Yulia
ALCHEMY:Journal of Chemistry Vol 12, No 2 (2024): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v12i2.23757

This study aims to determine the potential of ethanol extract of elo fruit (Ficus racemosa L.) as a photo-aging lotion preparation. Photo aging preventive lotion formulation was made in 5 variations. Each formulation was tested for characterization of physical properties in the form of pH test, diameter of spreadability, homogeneity, and stability through 3 cycles. Ethanol extract of elo fruit was obtained using a simple maceration method in 96% ethanol solvent. Based on the results of the qualitative phytochemical test, the ethanol extract of elo fruit contains flavonoid and tannin compounds. The pH test results show that the lotion formulation has a range of 7.27 - 7.65. The results of the diameter of spreadability using a weight of 200 g, 400 g, and 600 g obtained a diameter in the range of 2.16 cm - 3.70 cm. Each lotion formulation has good homogeneity. The results of the stability test against 4oC and room temperature showed no changes in aroma, color, and texture that occurred in each lotion formulation F1 - F5.

Physico-chemical characteristics of Figs Herbal Tea (Ficus racemosa L.) as a functional antidiabetic drink Dewi, Yuli Kusuma; Suryani, Novia
Journal of Natural Sciences and Mathematics Research Vol. 10 No. 2 (2024): December
Publisher : Faculty of Science and Technology, Universitas Islam Negeri Walisongo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/jnsmr.v10i2.23245

(Ficus racemosa L.) contain secondary metabolite compounds such as flavonoids, saponins, alkaloids, steroids, and tannins that have potential as a source of antioxidants. This study aims to determine the drying temperature variations on physicochemical characteristics of figs as an antidiabetic functional drink. The research methods begin by drying figs at various temperature (50°C, 60°C, and 70°C). The phytochemical test was followed by qualitative color change. The moisture content measurement was done using the thermogravimetric method. Then, the FTIR instrument identified the functional groups of organic compounds. Phytochemical analysis revealed the presence of flavonoids and tannins in all tea samples, regardless of drying temperature. FTIR spectroscopy confirmed the presence of phenolic compounds, characterized by O-H, Csp, and C=O enol groups. The pH of the tea at 50°C, 60°C, and 70°C, was 6.13; 5.64; and 5.59, the acidity of the pH obtained was indicated by the presence of phenolic compounds in all samples. The tea's moisture content was found to be within the Indonesian National Standard (<8%) at 60°C and 70°C, were 5.50% and 4.10%. Thus, fig tea, dried at 60°C or 70°C, can be developed as a functional antidiabetic drink.

Phytochemical Screening of Bioactive Compounds and Antioxidant Activity of Different Extracts From the Fruits and Barks of Ficus racemosa Suryani, Novia; Damalianti, Yulia; Hidayanti, Baiq Rauhil; Mustariani, Baiq Ayu Aprilia; Dewi, Yuli Kusuma
Jurnal Kimia Riset Vol. 10 No. 1 (2025): June
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v10i1.72078

Ficus racemosa, also known as the fig plant, is renowned for its diverse medicinal properties. In light of this, our research aims to study the phytochemical compounds present in several extracts of fruits and barks of Ficus racemosa, as well as the antioxidant activity explored in the gradual solvent polarities (methanol, ethyl acetate, and hexane). The dried fruit and bark of Ficus racemosa were utilized, and extraction was obtained through successive extraction at room temperature following the cold maceration technique. Preliminary phytochemical screening of fruit and bark extracts revealed the presence of alkaloids, flavonoids, and tannins. The extracts were subjected to antioxidant activities by the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) assay. Antioxidant capacity revealed the IC50 value of the methanol and ethyl acetate fruit extract of Ficus racemosa, which offered a strong capacity of 67.114 μg/mL and 69.149 μg/mL. These results indicate that the crude extract from Ficus racemosa fruit could serve as a candidate for a natural antioxidant against free radicals.

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