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All Journal JBN (Jurnal Bedah Nasional) Folia Medica Indonesiana
Suryawisesa, Ida Bagus Made
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience

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The Accuracy of FNAB as Diagnostic Tool For Thyroid Cancer Compared to Anatomical Pathology Results as Gold Standard at Sanjiwani Hospital, Gianyar Yasa, I Nyoman Wawan Tirtha; Maheswari, Luh Putu Dewanda; Suryawisesa, Ida Bagus Made; Irawan, Hendry; Sudarsa, I Wayan; Bharata, Made Dwi Yoga; Widarsa, I Ketut Tangking
JBN (Jurnal Bedah Nasional) Vol 8 No 2 (2024): JBN (Jurnal Bedah Nasional)
Publisher : Program Studi Ilmu Bedah, Fakultas Kedokteran Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JBN.2023.v08.i02.p02

Abstract

Aim: The aim of this study was to assess the accuracy of fine needle aspiration biopsy (FNAB) as a diagnostic tool for thyroid cancer in Sanjiwani Hospital, Gianyar. Methods: This study used a diagnostic test method with a retrospective cross-sectional design. A total of 138 cases of thyroid nodules that received FNAB and anatomical pathology examinations were selected consecutively. The level of accuracy was determined from the number of sensitivity, specificity, positive predictive value and negative predictive value. Results: The results of this study showed a low sensitivity 11.53%, but high specificity 100%, positive predictive value 100%, and negative predictive value 82.96% of FNAB. The accuracy of FNAB as diagnostic tools of thyroid cancer was 83,3% compared with anatomical pathology results as gold standard. Conclusion: FNAB is less accurate to diagnose thyroid cancer, but FNAB examination is accurate in differentiate benign and cancer lesion in thyroid nodule.
Validity of Wagner, SINBAB, PEDIS, and WIFI Scoring Systems to Assess Risk of Amputation in Patients with Diabetic Foot Ulcers Gunawan, I Made Kasmadi; Budiarta, Ida Bagus; Mahadewa, Tjokorda Gde Bagus; Suryawisesa, Ida Bagus Made; Wibawa, I Gusti Agung Bagus Krisna; Ariyanta, Kadek Deddy
JBN (Jurnal Bedah Nasional) Vol 8 No 2 (2024): JBN (Jurnal Bedah Nasional)
Publisher : Program Studi Ilmu Bedah, Fakultas Kedokteran Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JBN.2024.v08.i02.p04

Abstract

Aim: This study aims to determine validity of the Wagner, SINBAD, PEDIS, and WIFI scoring systems in assessing the risk of amputation in patients with diabetic foot ulcers at Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar. Methods: This research is an observational study of diagnostic tests with a cross-sectional design. The sample in this study was selected by consecutive sampling from 1 January 2022 to 31 December 2022 with total of 72 respondents.Results: Wagner score test obtained sensitivity 77.2%, specificity 80.0%, PPV 93.6%, NPV 48%, accuracy 77.7%, and RR 1.8. PEDIS score test results obtained sensitivity 82.5%, specificity 86.7%, PPV 95.9%, NPV 56.5%, accuracy 83.3%, and RR 2.2. The results of the SINBAD test score obtained sensitivity 78.9%, specificity 66.7%, PPV 90.0%, NPV 45.5%, accuracy 76.3%, and RR 1.6. WIFI score test obtained sensitivity 89.5%, specificity 66.7%, PPV 91.1%, NPV 62.5%, accuracy 84.7%, and RR 2.4. Conclusion: The WIFI score has better sensitivity and accuracy compared to score Wagner, SINBAD, and PEDIS so it is recommended to use the WIFI score to assess the risk of amputation in diabetic foot ulcer patients.
The Effects of Purple Sweet Potato (Ipomoea Batatas L.) Ethanol Extract on Bladder Urothelial Layer and Smooth Muscle Thicknesses in Menopausal Female Wistar Rats Putra, Bismantara Aditya; Santosa, Kadek Budi; Niryana, I Wayan; Golden, Nyoman; Duarsa, Gede Wirya Kusuma; Suryawisesa, Ida Bagus Made
Folia Medica Indonesiana Vol. 59, No. 2
Publisher : Folia Medica Indonesiana

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Abstract

Highlights: Purple sweet potatoes cultivated in Bali, Indonesia, were found to be rich in phytoestrogen due to the high levels of anthocyanin-type flavonoids. The phytoestrogen in purple sweet potato ethanol extract demonstrated estrogenic activity and the potential to substitute hormone replacement therapy (HRT) as the treatment of lower urinary tract symptoms. Abstract Postmenopausal women experience estrogen hormone deficiency, which can cause thinning of the smooth muscle and urothelial layer of the bladder, leading to lower urinary tract symptoms (LUTS). Hormone replacement therapy (HRT) has been the primary choice for addressing these problems. However, long-term prescription of HRT can result in several adverse effects, including a higher risk of breast cancer and cardiovascular diseases. Phytoestrogen, an estrogen-like compound derived from plants such as purple sweet potatoes (Ipomoea batatas L.), contains anthocyanin that could serve as a better alternative to estrogen replacement therapy. This study aimed to demonstrate the effects of phytoestrogens in purple sweet potatoes on the histomorphology of the bladder in menopausal female Wistar rats (Rattus norvegicus). This experimental study used a posttest-only control group design. A total of 36 Wistar rats undergoing ovariectomy were randomly assigned into two groups, with 18 samples in each group. The experimental group received the purple sweet potato ethanol extract orally, while the control group received a placebo. The structures of the smooth muscle and urothelial layer of the bladder were observed using a microscope. Data were analyzed using an independent t-test to compare bladder smooth muscle and urothelial layer thickness between groups, with a significance of p<0.05. A normality test was performed to determine the normal distribution of the data. Normally distributed data were assessed to find the mean and standard deviation (SD). Significant differences were found in the mean thickness of the smooth muscle and urothelial layer between both groups (p=0.00), with both being thicker in the experimental group. In conclusion, phytoestrogens in purple sweet potatoes can influence the histomorphology of the bladder. Ovariectomized female Wistar rats that received purple sweet potato ethanol extract exhibited thicker smooth muscle and urothelial layer of the bladder.
Co-Authors Ariyanta, Kadek Deddy Bharata, Made Dwi Yoga Budiarta, Ida Bagus Gede Wirya Kusuma Duarsa Hendry Irawan I Made Kasmadi Gunawan, I Made Kasmadi I W. Sudarsa I Wayan Niryana K Tangking Widarsa Kadek Budi Santosa Maheswari, Luh Putu Dewanda Nyoman Golden Putra, Bismantara Aditya Tjokorda Gde Bagus Mahadewa Wibawa, I Gusti Agung Bagus Krisna Yasa, I Nyoman Wawan Tirtha