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All Journal Narra J Kenanga : Journal of Biological sciences and Applied Biology Jurnal Natural
KUSUMA, HENDRIX INDRA
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Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Earth & Planetary Sciences Energy Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Physics Public Health

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A comparison study of headache characteristics and headache-associated quality-of-life of COVID-19 and non-COVID-19 patients Mutiawati, Endang; Kusuma, Hendrix Indra; Fathima, Raisha; Syahrul, Syahrul; Musadir, Nasrul
Narra J Vol. 2 No. 3 (2022): December 2022
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v2i3.93

Abstract

Headache is prevalent in coronavirus disease 2019 (COVID-19) patients. The main objective of this study was to compare the characteristics of COVID-19-associated headache to non-COVID-19 headache. The quality-of-life (QoL) and its associated determinants between COVID-19 and non-COVID-19 patients were also compared. A cross-sectional study was conducted in Banda Aceh, Indonesia. Headache and QoL were assessed using the International Classification of Headache Disorders, version 3 (ICHD-3), and the 36-item Short Form Health Survey (SF-36), respectively. Factors associated with poor QoL in COVID-19 and non-COVID-19 patients were examined using logistic regression. A total of 356 headache patients were included: 215 COVID-19 and 141 non-COVID-19 patients. Our data suggested that the headache in COVID-19 patients was bilateral; pain centered on one specific area with a pulsating or pressing sensation; pain intensity ranging from moderate to severe; and the frequency ranging from more than twice per week to every day. Non-COVID-19 headache was bilateral; pain centered on one side of the head resembling a migraine with pulsating or pressing sensation; mild to moderate pain intensity; and the frequency of one or two times per month. In COVID-19, low QoL was associated with unemployment status, having non-health-related jobs, having used painkillers to reduce the pain, having long duration of headache, having more frequency of attacks, and having headaches that were worsened by activities or light, and having additional symptom during a headache attach. In non-COVID-19 patients, poor QoL was associated with the use of painkillers, long duration of headache, and having conditions that aggravate the headache. To prevent long-term effects of headache associated with COVID-19, studies exploring the photobiology of headache are  needed, along with the necessity of having standardised guideline on headache prevention.
POTENSI KEBERADAAN ORANGUTAN DI HUTAN GAMBUT RAWA TRIPA - ANALISIS SARANG DAN POHON PAKAN Kusuma, Hendrix Indra; Rayhannisa; Akbar, Novrizal; Fithri, Aida; Sari, Widya; Ruskhanidar
KENANGA : Journal of Biological Sciences and Applied Biology Vol. 5 No. 1 (2025): April 2025
Publisher : Program Studi Biologi Fakultas Sains dan Teknologi Universitas Islam Negeri Ar-Raniry Banda Aceh, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/kenanga.v5i1.5959

Abstract

The orangutan, a vital component of the rainforest ecosystem, is increasingly threatened by habitat loss and fragmentation. Identifying orangutan nests and feeding trees is an important elements in understanding the habitat's capacity to sustain this species. Using the transect method, this study was conducted on 40 grids out of a total of 623 grids in the Tripa area that are still covered by forest. This study aimed to record the presence of orangutan nests and identify various plant species that serve as food sources for orangutans. The result revealed the discovery of orangutan nests in 7 locations, most of which were categorized as type C (old) and type D (very old). A total of 13 potential orangutan food plant species were found in the Rawa Tripa forest area, consisting of the families Moraceae, Euphorbiaceae, Annonaceae, Myrtaceae, Myristicaceae, Apocynaceae, Piperaceae, Dipterocarpaceae, Urticaceae, and Pandanaceae. This suggest that these areas may have supported a significant orangutan population in the past, but their current activity appears to be declining. The findings underscore the need for conservation efforts, as the continued survival of orangutans is crucial not only for their species but also for the ecological health of the forests they inhabit. Keywords : orangutan, peat swamp forest Tripa, Leuser Ecosystem, nest analysis, habitat loss, conservation
The immunostimulant effect of jamblang stem bark (Syzygium cumini L.) ethanol extract against mice macrophages phagocytosis activity and capacity SARI, WIDYA; SAFITRI, NOVI; IZZAZAYA, ANNISA; KUSUMA, HENDRIX INDRA; SYAHFITRI, WIDYA; ROSNIZAR, ROSNIZAR
Jurnal Natural Volume 25 Number 2, June 2025
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v25i2.44121

Abstract

This study aims to determine the effect of administering Jamblang Stem Bark Ethanol Extract (Syzygium cumini L.) (JSBEE) on the activity and phagocytosis capacity of macrophages in mice (Mus musculus) infected with Staphylococcus aureus bacteria. The research method used a completely randomized design (CRD) with five treatments and five repetitions, conducted in-vitro and in vivo test. The treatments for in vitro involved administering distilled water (T0), Stimuno (T1), and JSBEE at concentrations of 10 ppm (T2), 100 ppm (T3), and 1000 ppm (T4). Subsequently, in vivo treatment was conducted using distilled water (T0), stimuno (T1), JSBEE at 10 mg/kg (T2), 100 mg/kg (T3), and 1000 mg/kg (T4). Initially, mice underwent in vivo administration of JSBEE, administered orally via catheter tip, with a dosage of 1 mL per 10 g of body weight. JSBEE was administered orally for 10 days, followed by infection with S. aureus on the 11th day. The in vitro tests were conducted by isolating macrophage cells from the intraperitoneal fluid, to which S. aureus and JSBEE were added. Intraperitoneal fluid collected from the mice was used to prepare smears using the thin blood smear method and Giemsa staining. Macrophage phagocytosis activity was observed and assessed based on the percentage activity formula, and the phagocytic capacity of macrophages was measured by the number of S. aureus cells phagocytosed. The results indicated that JSBEE significantly affected (P0.05) both the activity and phagocytic capacity of macrophages in vivo and in-vitro. The best concentration of JSBEE for increasing both the activity value and phagocytic capacity of macrophages was 100 ppm (T3).
Co-Authors Aida Fithri Akbar, Novrizal ENDANG MUTIAWATI, ENDANG Fathima, Raisha IZZAZAYA, ANNISA Novi Safitri Rayhannisa Rosnizar, Rosnizar Ruskhanidar Syahfitri, Widya Syahrul Syahrul Widya Sari