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Journal : Jurnal Inkofar

PEMANFAATAN MIKROBA ENDOFIT ASAL TANAMAN OBAT SEBAGAI SUMBER BAHAN OBAT Mayuri, Nindya Sekar
Jurnal Inkofar Vol 8, No 1 (2024)
Publisher : Politeknik META Industri Cikarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46846/jurnalinkofar.v8i1.354

Abstract

Tingginya permintaan obat yang berasal dari tanaman obat dengan keterbatasan tanaman dalam waktu tumbuh dan ketersedian tanaman tersebut di alam, menjadikan produksi senyawa metabolit dari tanaman obat sangat terbatas sehingga diperlukan pencarian senyawa baru dengan efektivitas yang lebih baik. Mikroba Endofit merupakan mikroba yang hidup membentuk koloni di dalam jaringan tanaman tanpa merugikan tanaman inang. Setiap tanaman dapat mengandung beberapa mikroba endofit yang berpotensi menghasilkan metabolit sebagai akibat koevolusi atau terjadi transfer genetik dari tanaman inang kepada mikroba endofit. Pemanfaatan mikroba endofit asal tanaman obat untuk memproduksi metabolit yang dihasilkan oleh tanaman obat merupakan salah satu solusi alternatif untuk memproduksi obat tanpa terkendala waktu tumbuh dan ketersedian tanaman obat serta resistensi mikroba.
PEMANFAATAN MIKROORGANISME PENGHASIL KOLAGEN SEBAGAI PENGGANTI KOLAGEN BABI DALAM SKIN CARE HALAL Mayuri, Nindya Sekar; Dianah, Pepin Nur; Asifadilah, Ayu
Jurnal Inkofar Vol 8, No 2 (2024)
Publisher : Politeknik META Industri Cikarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46846/jurnalinkofar.v8i2.331

Abstract

Collagen is a protein material that has tensile strength and a fiber-shaped structure, and is found in many higher vertebrates with an amount of around 25-30% of the protein that makes up the body. Currently, collagen is widely used as a basic ingredient in beauty products. The collagen that is most widely marketed generally comes from the skin and bone tissue of cows or pigs, the safety and halal of which need to receive more attention, so an alternative source of collagen that is safe and halal is needed to replace pork collagen. One alternative that can be used is to use collagen-producing microorganisms. This research uses library research (Library Research) with documentation methods to analyze library results. The results of the analysis show that the bacteria Streptococcus pyrogenes is a potential bacteria that can be used to replace pork collagen. Recombinant technology by manipulating the hCol gene as human collagen and bCol as recombinant bacterial collagen Scl2. This manipulation can optimize molecular and biological properties. Apart from that, to increase the stability of the S.pyrogenes Scl2 bacterial collagen, the insertion of hydroxyproline was carried out by combining direct co-translation of modified amino acids using the codon for proline in inserting the gene construction. This GMO (Genetically Modified Organism) product is certainly halal because it does not use ingredients containing pork.
GAMBARAN ANGKA LEMPENG TOTAL BAKTERI PADA BEDAK USIA 12 BULAN SETELAH DIGUNAKAN Mayuri, Nindya Sekar; Yusuf, Nabila Islami; Mareta Hera Siswana, Dwi Risyani; Tantiani, Aisyah Putri; Hafid, Naila Akfalia
Jurnal Inkofar Vol 9, No 1 (2025)
Publisher : Politeknik META Industri Cikarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46846/jurnalinkofar.v9i1.421

Abstract

The high number of powder users and the side effects caused by using powder that contains bacteria, then research is needed related to the Total Plate Count of bacteria in powder aged 12 months after use. The research method used in this study is an experimental method. The powder sample used was 12 months old after the powder was used without using a particular brand. The results of the calculation of the number of bacterial colonies showed that the sample with the highest number of colonies was sample S as much as 7.9 x 10^3 cfu/gram then sample W as much as 5.5 x 10^2 cfu/gram and sample L as much as <3.0 x 10^2 cfu/gram. As for the WB sample, there was no bacterial growth the same as the control, namely <1.0 x 10^1 cfu/gram. The color of the bacterial colonies that were successfully isolated was mostly white and 1 colony was clear. While for the shape of the colony consists of Spindle, Irregular, Punctiform, Circular. For the elevation of all bacterial colonies is Convex with margins consisting of Entire and Endulate. 
FORMULASI DAN EVALUASI SABUN PADAT MINYAK ADAS BINTANG (Illicium verum) DENGAN VARIASI KONSENTRASI MINYAK KELAPA, MINYAK SAWIT DAN MINYAK ZAITUN Azzahra, Fauzia; Ramadhani, Intan Puspita; Fitriani, Rima; Mayuri, Nindya Sekar
Jurnal Inkofar Vol 9, No 1 (2025)
Publisher : Politeknik META Industri Cikarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46846/jurnalinkofar.v9i1.458

Abstract

Soap bar is a cleansing preparation created by the saponification reaction. The qualities of soap bars vary depending on the oil composition. Furthermore, additional materials, such as essential oils, could be added to boost the product's value and benefits. The aim of this study is to generate good-quality soap bars using Illicium verum as active ingredients and varying oil concentrations applying the cold process method. The developed soap bar was then examined for its organoleptic properties, pH, moisture content, foam stability, and free fatty acid. On the 7th day, F1, F2, and F3 had pH values of 10.36 ± 0.012, 10.30 ± 0.038, and 10.15 ± 0.095, moisture content (%) of 5.21 ± 0.16, 4.76 ± 0.40, and 7.80 ± 0.58, foam stability (%) of 89.4 ± 0.06, 72.9 ± 0.07, and 74.8 ± 0.10, and free fatty acid (%) of 0.342 ± 0.024, 0.301 ± 0.024, and 0.328 ± 0, respectively. On the 14th day, F1, F2, and F3 had pH values of 10.09 ± 0.121, 10.29 ± 0.015, and 10.18 ± 0.067, moisture content of 4.55 ± 0.46, 3.49 ± 0.29, and 6.67 ± 0.29, foam stability of 91.3 ± 0.02, 91.7 ± 0.05, and 86.2 ± 0.04, and free fatty acid of 0.478 ± 0.063, 0.586 ± 0.046, and 0.560 ± 0.024, respectively. Both the results from the 7th and 14th days comply with the specifications. The variation in oil concentration influences soap bar qualities such as organoleptic, moisture content, and pH.Keywords : Soapbar, Illicium verum, Coconut oil, Palm oil, Olive oil