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All Journal Jurnal Riset Kesehatan Jurnal Ilmu Kedokteran dan Kesehatan 3BIO: Journal of Biological Science, Technology and Management BIOEDUPAT: Pattimura Journal of Biology and Learning JUKEJ: Jurnal Kesehatan Jompa Jurnal Sains dan Kesehatan
Mayuri, Nindya Sekar
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Effectiveness of Sengon Ethyl Acetate Extract and Bamboo Liquid Smoke as Disinfectants Anisa, Divia; Marlina, Rina; Juniar, Fadia Rahma; Nurjaman, Deni; Fadhila, Feldha; Mayuri, Nindya Sekar; Rumidatul, Alfi
BIOEDUPAT: Pattimura Journal of Biology and Learning Vol 5 No 1 (2025): Bioedupat : Pattimura Journal of Biology and Learning
Publisher : Program Studi Pendidikan Biologi, Pascasarjana, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/bioedupat.v5.i1.pp287-293

Abstract

The absence of environmental sanitation can influence the transmission of infectious diseases, exemplified as toilets tainted with dangerous microbes. Prevention typically employs disinfectants; nevertheless, their adverse effects might lead to skin and respiratory discomfort. Flavonoids, tannins, and saponins in sengon wood possess antibacterial properties and can serve as alternative materials. The study aimed to assess the efficacy of combining sengon wood extract and bamboo stem liquid smoke as a disinfectant. The experimental methodology employed in vitro testing through an inhibitory assay and in vivo testing utilizing a swab on the surface, assessing the effects pre- and post-swabbing. The in vitro results indicated that the most substantial inhibitory zone was observed with a 40:60 ratio for Salmonella typhimurium ATCC 25241, measuring 11.8 mm; for Candida albicans ATCC 10231, a 30:70 ratio yielded 5.33 mm; and for Aspergillus flavus ATCC 9643, a 30:70 ratio resulted in 5.5 mm. In vivo, swabs from the table yielded an average reduction of 92% in bacterial colonies and 73% in fungal colonies. Conclusion: The amalgamation of sengon twig wood extract and bamboo stem liquid smoke exhibits potential as a disinfectant. Keywords: Liquid smoke, bamboo sticks, disinfectant, sengon wood
Efektivitas Ekstrak Kayu Sengon (Falcataria moluccana) dan Asap Cair Batang Bambu (Bambusa sp) sebagai Disinfektan: Effectiveness of Sengon Wood Extract (Falcataria moluccana) and Bamboo Stem Liquid Smoke (Bambusa sp) as Disinfectants Anisa, Divia; Marlina, Rina; Juniar, Fadia Rahma; Nurjaman, Deni; Fadhila, Feldha; Mayuri, Nindya Sekar; Rumidatul, Alfi
Jurnal Sains dan Kesehatan Vol. 7 No. 2 (2025): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v7i2.2431

Abstract

Lack of cleanliness of the surrounding environment can influence the spread of infectious diseases, such as toilets being contaminated by pathogenic microorganisms. It is common for prevention to use disinfectants, but the negative impact of using them can cause skin and respiratory irritation. The objective of this research is to determine the effectiveness of the combination of sengon twig wood extract and bamboo stem liquid smoke as a disinfectant. The method of this research is uses an experimental design where testing is carried out in vitro using an inhibition test and in vivo using a swab on a table by looking at the effects before and after the swab. Results: In vitro, the largest inhibition zone was formed in a combination ratio of 40:60 for Salmonella typhimurium ATCC 25241 of 11.8 mm; Candida albicans ATCC 10231 in comparison 30:70 was 5.33 mm; Aspergillus flavus ATCC 9643 in a ratio of 30:70 of 5.5 mm. In vivo, using swabs on the table, the average reduction in the number of bacterial colonies was 92% and in fungi the average was 73%. The combination of sengon twig wood extract and bamboo stem liquid smoke has the potential to be a disinfectant Keywords:          Liquid smoke, bamboo sticks, disinfectant, sengon twigs   Abstrak Kurangnya kebersihan lingkungan sekitar dapat mempengaruhi penyebaran penyakit infeksi, seperti toilet yang tercemari oleh mikroorganisme patogen.  Lumrahnya pencegahan menggunakan disinfektan, namun dampak negatif penggunaanya dapat menyebabkan iritasi kulit dan pernafasan. Tujuan penelitian ini untuk mengetahui efektivitas kombinasi ekstrak kayu ranting sengon dan asap cair batang bambu sebagai disinfektan. Metode penelitian ini menggunakan desain eksperimental dimana dilakukan pengujian secara in vitro menggunakan uji daya hambat dan in vivo menggunakan swab pada meja dengan melihat efek sebelum dan setelah swab. Secara in vitro terbentuk zona hambat paling besar pada kombinasi perbandingan 40:60 untuk Salmonella typhimurium ATCC 25241 sebesar 11.8 mm; Candida albicans ATCC 10231 di perbandinga 30:70 sebesar 5.33 mm; Aspergillus flavus ATCC 9643 di perbandingan 30:70 sebesar 5.5 mm. In vivo melalui swab pada meja diperoleh nilai rata-rata penurunan jumlah koloni bakteri  sebesar 92% dan pada jamur rata-rata sebesar 73%. Kombinasi ekstrak kayu ranting sengon dan asap cair batang bambu berpotensi sebagai disinfektan Kata Kunci:         Asap cair, batang bambu, disinfektan, kayu ranting sengon  
Effectiveness as a Disinfectant of Ethyl Acetate Extracted from Sengon Twig Bark (Falcataria Moluccana) and Bamboo Stem Liquid Smoke (Bambusa sp.) Nabila, Hasna Putri; Yuliani, Septa; Alifah, Aqil; Qomariah, Annisa Nur; Sugara, Yuliannisa; Rumidatul, Alfi; Fadhila, Feldha; Mayuri, Nindya Sekar
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 8 (2025): Volume 12 Nomor 8
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i8.19621

Abstract

Penyakit infeksi yang disebabkan oleh mikroba patogen masih menjadi suatu masalah kesehatan utama di seluruh dunia. Pada umumnya, pencegahan dilakukan dengan penyemprotan disinfektan berbahan dasar kimia, namun penggunaananya dapat menimbulkan kerusakan kulit sehingga diperlukan alternatif lain, salah satunya dengan menggunakan bahan alami yaitu ekstrak etil asetat kulit ranting sengon (Falcataria moluccana) dan batang bambu (Bambusa sp.). Mengetahui efektivitas antimikroba ekstrak etil asetat kulit ranting sengon (Falcataria moluccana) dan asap cair batang bambu (Bambusa sp.) sebagai disinfektan. Menggunakan rancangan eksperimental. Data diambil dari 5 perlakuan pada metode difusi menggunakan campuran ekstrak etil asetat kulit ranting sengon (Falcataria moluccana) dan asap cair batang bambu (Bambusa sp.) dengan masing-masing perbandingan 50:50, 40:60, 30:70, 20:80, 10:90 kemudian hasil terbaik dilakukan uji swab pada meja. Pada metode difusi didapatkan hasil terbaik yaitu pada perbandingan 40:60 dan 20:80. Uji swab menghasilkan persentase penurunan bakteri sebesar 78,93% dan persentase penurunan jamur sebesar 83,27%. Ekstrak etil asetat kulit ranting sengon (Falcataria moluccana) dan asap cair batang bambu (Bambusa sp.) memiliki sifat antimikroba sehingga dapat dijadikan sebagai disinfektan.
Utilization of Roots of Muli Banana Plants (Musa acuminata Linn.) as Antibiotics and Antiseptics Nainggolan, Ribka Debora; Handayani, Kusuma; Mayuri, Nindya Sekar; Rumidatul, Alfi
BIOEDUPAT: Pattimura Journal of Biology and Learning Vol 5 No 2 (2025): Bioedupat : Pattimura Journal of Biology and Learning
Publisher : Program Studi Pendidikan Biologi, Pascasarjana, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/bioedupat.v5.i2.pp335-344

Abstract

Diseases caused by bacteria can usually be combated by administering antibiotics and using antiseptics. However, there are some groups of pathogens, such Escherichia coli as well as Staphylococcus aureus, which are highly resistant to the antibiotics amoxicillin, penicillin, tetracycline and chloramphenicol. One of the efforts to control these bacteria is by using bioactive compounds derived from plants. Banana plants contain secondary metabolite compounds flavonoids, saponins, and tannins that can act as anti-infective agents, including muli banana (Musa acuminata Linn.). Banana plant roots as natural ingredients can be an alternative to antiseptics because they contain antibacterial compounds with milder side effects than long-term use of alcohol-based antiseptics that can reduce skin moisture. This study was conducted to determine the efficacy of banana muli root extract (M. acuminata Linn.) as an antibiotic and antiseptic. The hypothesis in this study is that the root extract at a certain concentration is thought to have effectiveness as an antibiotic (E. coli) and antiseptic (S. aureus). In this study, the Kirby-Bauer method was applied by agar diffusion and the results of the inhibition zone test were formed around the paper disc. The results showed that the optimum efficacy of muli banana root extract (M. acuminata Linn.) as an antibiotic (E. coli ATCC 25922) was at a concentration of 95% (2.96 mm) and as an antiseptic (S. aureus ATCC 25923) at a concentration of 75% (9.1 mm).
Effectiveness of Tea Leaf (Camellia sinensis) Liquid Smoke as an Antiseptic Rohmah, Fitriani Nurhidayati; Alamsyah, Muhamad Thamrin; Nurjana, Siti; Fadhila, Feldha; Mayuri, Nindya Sekar; Rumidatul, Alfi
3BIO: Journal of Biological Science, Technology and Management Vol. 6 No. 1 (2024)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2024.6.1.1

Abstract

Microbes are often the cause of infectious diseases; one method of prevention is to use antiseptics. Excessive use of antisep- tics can cause mild to severe side effects, so an alternative antiseptic is needed. Liquid smoke is an alternative raw material to produce antiseptics because its main component can be used as an inhibitor of microbial growth. This study aims to determine the effectiveness of tea-leaf liquid smoke as an antiseptic against microbial growth in vivo and in vitro. The method for producing liquid smoke via pyrolysis involves distilling grade 3 liquid smoke to generate grade 1 and grade 2 liquid smoke. The in vitro test uses a microbial growth inhibition test with grade 1 and 2 liquid smoke concentrations of 35%, 50%, and 75%. The microbes used were Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 25923, Candida albicans ATCC 10231, and Aspergillus flavus ATCC 9643. The in vivo test uses the swab test method on the palm of the hand. The results of the invitro test showed that the largest inhibition zone of tea leaf liquid smoke was obtained using grade 2 liquid smoke with a concentration of 75%.The results of the in vivo test showed that the effectiveness of tea leaf liquid smoke was 80% against bacteria and 85% against fungi. Based onthe results of the study, it can be concluded that tea leaf liquid smoke (Camellia sinensis) has potential as an antiseptic.
Effectiveness of Bamboo Stick Liquid Smoke (Bamboo sp.) With Methanol Extract of Sengon Twig Wood (Falcataria moluccana) as a Disinfectant Nabillah, Hurient Sani; Sonya, Luluil Fajry Thasya; Fitriani, Dilla Saphira; Muzjahidah, Nelly Siti; Vaolina, Putri; Fadhila, Feldha; Rumidatul, Alfi; Mayuri, Nindya Sekar
Jurnal Riset Kesehatan Vol 13 No 1 (2024): MEI 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrk.v13i1.10597

Abstract

Pathogenic microorganisms that cause infectious diseases are widely spread in the environment, especially in public places that allow microorganisms to multiply. Disinfectants are used to prevent the spread of these microorganisms. The use of chemical-based disinfectants can cause side effects, so it is necessary to look for alternatives from natural materials, such as a mixture of bamboo stem liquid smoke and methanol extract from Sengon twig wood. The purpose of this study was to determine the effectiveness of a mixture of bamboo stem liquid smoke and methanol extract of Sengon twig on bacteria and fungi. This research method began with an inhibition test of the disc and well diffusion method with five comparison treatments (50:50, 40:60, 30:70, 20:80, 10:90) to obtain the most effective comparison of the volume of 100% bamboo stem liquid smoke mixture and 11% sengon twig wood methanol extract, then tested using the Total Plate Count (TPC) method with swab samples on wooden tables. The results showed that the most effective comparison of the volume of 100% bamboo stem liquid smoke mixture and 11% sengon twig wood methanol extract was the volume ratio of 50:50 from the results of the inhibition zone on Salmonella typhimurium with a diameter of 10.3 mm. The results of the mixed effectiveness test with a ratio of 50:50 with the swab test on the table showed a decrease in the number of bacteria (51%) and fungi (65%). This shows that the mixture of bamboo stem liquid smoke and methanol extract of Sengon twig wood is effective as a disinfectant.
Toksisitas Akut dan Efek Protektif Ekstrak Etanol Schima wallichii terhadap Histopatologi Hati dan Ginjal Mencit yang Diinduksi Aloksan Risa, Tiara Nova; Rahmawati, Mutia; G R, Lutfi Khoiriyah; Kodariah, Liah; Mayuri, Nindya Sekar; Rumidatul, Alfi
JUKEJ : Jurnal Kesehatan Jompa Vol 5 No 1 (2026): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol5.Iss1.2491

Abstract

Diabetes melitus (DM) merupakan penyakit metabolik kronis yang memicu komplikasi pada hati dan ginjal melalui mekanisme stres oksidatif. Tanaman Puspa (Schima wallichii (D.C) Korth) mengandung senyawa bioaktif antioksidan seperti flavonoid dan tanin yang berpotensi sebagai agen antidiabetes. Penelitian ini bertujuan mengevaluasi toksisitas akut serta efek protektif ekstrak etanol ranting S. wallichii terhadap gambaran histopalogi hati dan ginjal mencit (Mus musculus) yang diinduksi aloksan. Mencit jantan diinduksi aloksan 150 mg/kgBB secara intraperitoneal, kemudian diberikan ekstrak secara oral dengan dosis 98 mg/kgBB (P1) dan 196 mg/kgBB (P2). Parameter yang diamati meliputi berat badan, kadar glukosa darah, gejala toksisitas klinis, serta perubahan mikroskopis jaringan hati dan ginjal. Hasil menunjukkan tidak terdapat mortalitas maupun gejala toksik berat selama 14 hari pengamatan, sehingga nilai LD₅₀ semu dikategorikan praktis tidak toksik (>196 mg/kgBB). Secara histopatologis, kelompok P2 menunjukkan perbaikan signifikan pada jaringan hati (p < 0,05) yang ditandai dengan penurunan derajat degenerasi dan nekrosis. Pada ginjal terdapat tren penurunan skor kerusakan secara deskriptif, namun belum menunjukkan perbedaan bermakna secara statistik (p > 0,05). Dapat disimpulkan bahwa ekstrak ranting S. wallichii aman pada dosis uji, efektif memperbaiki kerusakan hati (hepatoprotektif), serta memiliki potensi nefroprotektif terbatas pada model mencit diabetes.
Co-Authors Alamsyah, Muhamad Thamrin Alifah, Aqil Anisa, Divia Asifadilah, Ayu Dianah, Pepin Nur Fadhila, Feldha Fauzia Azzahra, Fauzia Fitriani, Dilla Saphira Fitriani, Rima G R, Lutfi Khoiriyah Hafid, Naila Akfalia Juniar, Fadia Rahma Kodariah, Liah Kusuma Handayani, Kusuma Mareta Hera Siswana, Dwi Risyani Muzjahidah, Nelly Siti Nabila, Hasna Putri Nabillah, Hurient Sani Nainggolan, Ribka Debora Nurjaman, Deni Nurjana, Siti Qomariah, Annisa Nur Rahmawati, Mutia Ramadhani, Intan Puspita Rina Marlina Risa, Tiara Nova Rohmah, Fitriani Nurhidayati Rumidatul, Alfi Sonya, Luluil Fajry Thasya Sugara, Yuliannisa Tantiani, Aisyah Putri Vaolina, Putri Yuliani, Septa Yusuf, Nabila Islami