Article Per Year (5 Year)
p-Index From 2020 - 2025
0.562
P-Index
This Author published in this journals
All Journal BIOEDUSCIENCE Jurnal Pharmacopoeia Riset Informasi Kesehatan
Putra, Rizky Yulion
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Nursing Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Sub-Acute Toxicity Test of Red Betel Leaves (Piper crocatum) on Liver Function in Male White Mice (Mus musculus) Using SGPT Test Andriani, Medi; Putra, Rizky Yulion; Asnadewi, Veni
BIOEDUSCIENCE Vol 8 No 3 (2024): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/14640

Abstract

Background: This research aims to investigate the sub-acute toxicity of red betel leaves (Piper crocatum) on liver function in male white mice (Mus musculus) using a serum glutamic-pyruvic transaminase (SGPT) test on a clinical photometer instrument. Methods: This research aims to investigate the sub-acute toxicity of red betel leaves (Piper crocatum) on liver function in male white mice (Mus musculus) using a test serum Glutamic Pyruvic Transaminase (SGPT) assay on a clinical photometer instrument. In this study, an experimental method was employed using a randomized block design, with 72 mice serving as research subjects and divided into eight treatment groups. Group 1 was given 0.5% Na CMC, group 2 as a positive control; group 3 was given a comparison of metformin; group 4 was given an extract with a dose of 100 mg/KgBB, group 5 was given the N-Hexane fraction with a dose of 100 mg/KgBB, group 6 was given the Ethyl Acetate fraction with a dose of 100 mg/KgBB, group 7 was given the N-Butanol fraction with a dose of 100 mg/KgBB, group 8 was given the Residual Water Fraction with a dose of 100 mg/KgBB, the treatment was carried out for 2, 4, 6 days, in the SGPT test used was serum. Results: The administration of extracts and fractions to animals did not cause Subacute Toxicity effects on the livers of male white mice. Looking at the SGPT (Serum Glutamic Pyruvic Transaminase) parameters, the activity of which was still within normal conditions, namely 25-200 µ/l. Conclusions: did not show any Subacute Toxicity effects as seen from the activity of the SGPT enzyme in the blood of male white mice (Mus musculus).
Pengaruh Pelayanan Informasi Obat Tb Paru Dengan Media Audio Visual Terhadap Tingkat Pengetahuan Pengawas Menelan Obat (PMO) Tuberculosis Paru Di Puskesmas X Di Kota Jambi Putra, Rizky Yulion; Sutrisno, Deny; Munti, Putri Delina Cupa
Jurnal Pharmacopoeia Vol 3 No 2 (2024): September 2024
Publisher : Poltekkes Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/jp.v3i2.864

Abstract

Kejadian tuberkulosis masih menjadi permasalahan di Indonesia. Keberhasilan penyembuhan tuberkulosis sangat tergantung pada kepatuhan penderita dalam minum obat. Supaya penderita patuh, pengawas menelan obat (PMO) wajib mempunyai pengetahuan yang baik tentang tuberkulosis. Riset ini bertujuan buat mengenali pengaruh pelayanan data obat TB paru lewat media audio visual terhadap tingkatan pengetahuan PMO TB Paru di Puskesmas X Kota Jambi. Desain riset yang digunakan merupakan kuantitatif dengan pendekatan Quasi- eksperimental. Riset dilaksanakan di Puskesmas X Kota Jambi pada bulan Mei hingga Juni 2024. Sampel penelitian terdiri dari 35 orang PMO yang dipilih. Rata-rata skor pengetahuan sebelum pemberian informasi obat TB paru melalui media audio visual adalah 17,31 dan meningkat menjadi 19,74 setelah intervensi. Analisis bivariat menemukan adanya pengaruh signifikan dari pemberian informasi obat melalui media audio visual terhadap pengetahuan PMO TB Paru di Puskesmas X Kota Jambi( p- value=0, 000). Bersumber pada hasil riset bisa disimpulkan kalau pemberian data obat lewat media audio visual efisien tingkatkan pengetahuan PMO TB Paru. Diharapkan Puskesmas menggunakan media audio visual dalam edukasi tuberkulosis kepada masyarakat.
Ultrasonic NaDES-based optimization of luteolin extraction technology from celery (Apium graveolens) for improved drug raw material independence Putra, Rizky Yulion; Mariska, Ruri Putri; Latifah, Putri Ningrum Nurin
Riset Informasi Kesehatan Vol 13 No 2 (2024): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/rik.v13i2.906

Abstract

Background: Natural deep eutectic solvents (NaDES) represent a significant advancement in the field of natural material extraction, offering a novel approach to the isolation of active compounds. The objective of this study was to develop a novel NaDES-based extraction method to achieve the highest percentage of luteolin compounds in celery (Apium graveolens) through ultrasonic treatment. Method: Choline chloride was employed as the hydrogen bonding acceptor (HBA), while lactic acid and malic acid served as the hydrogen bonding donors (HBD). Treatment optimization was conducted using Design Expert 7 software, with the variables comprising the HBA:HBD ratio, temperature, and time. Results: The optimal combination of NaDES solvents was identified as choline chloride: lactic acid and choline chloride: malic acid at a ratio of (4.71 mol: 4.76 mol) and (1.27 mol: 1.71 mol), respectively, at a temperature of 55.2°C. The optimal conditions were 40°C and 35.45°C, with a time of 15.63 minutes and 12.73 minutes, respectively, which yielded 2.2789% and 0.0102% with a desirability of 0.2788 and 0.0408, respectively. Conclusion: The optimal combination was identified as choline chloride: lactic acid, which demonstrated a gain of over 2%. Additionally, the combination of choline chloride: malic acid proved effective for luteolin extraction.
Co-Authors Andriani, Medi Asnadewi, Veni Latifah, Putri Ningrum Nurin Munti, Putri Delina Cupa Ruri Putri Mariska Sutrisno , Deny