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Profil Pasien Kanker Serviks di RS Awal Bros Batam Tahun 2020–2022 Jenifer, Debora; Serevina, Devy; Nurprilinda, Marliana
Majalah Kedokteran UKI Vol. 39 No. 2 (2023): MEI - AGUSTUS
Publisher : Fakultas Kedokteran Universitas Kristen Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33541/mk.v39i2.5898

Abstract

Kanker serviks adalah keganasan leher rahim yang disebabkan oleh Human Papilomavirus tipe 16 dan 18 dan ditularkan melalui hubungan seksual. Indonesia merupakan negara dengan kasus kanker serviks terbanyak di Asia Tenggara. Tujuan penelitian ini untuk mengetahui profil pasien kanker serviks di RS Awal Bros Batam tahun 2020-2022. Penelitian ini bersifat retrospektif dengan mengambil data rekam medis pasien kanker serviks. Sebanyak 97 orang subjek yang diteliti memiliki rentang umur 36-50 tahun (55,7%), menikah (99%), paritas 3-4´ (52,6%), berpendidikan SMA (50,5%), ibu rumah tangga (74,2%). Keluhan utama adalah perdarahan yang ditemukan pada 52 subjek dengan gambaran histopatologi karsinoma sel skuamosa (72,2%) dengan diferensiasi baik (44,3%). Kata kunci: Human Papilomavirus, karsinoma sel skuamosa, paritas, derajat diferensiasi Cervical cancer is a malignancy of the cervix caused by Human Papillomavirus types 16 and 18 and is transmitted through sexual contact. Indonesia is the country with the most cases of cervical cancer in Southeast Asia. The aim of this research is to determine the profile of cervical cancer patients at Awal Bros Hospital, Batam in 2020-2022. This research is retrospective in nature by taking medical record data from cervical cancer patients. A total of 97 subjects studied had an age range of 36-50 years (55.7%), married (99%), parity 3-4 times (52.6%), high school education (50.5%), housewives (74.2%). The main complaint was bleeding which was found in 52 subjects with histopathological features of squamous cell carcinoma (72.2%) with good differentiation (44.3%). Keywords: Human Papiloma Virus, squamous cell carcinoma, parity, degree of differentiation
Overview of Risk Factors for the Incidence of Pediculosis Capitis in Children Nurprilinda, Marliana; Sitanggang, Eva Silvia F; Djojosaputro, Mulyadi; Cahyawari, Dartri
Indonesian Journal of Global Health Research Vol 7 No 4 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i4.6907

Abstract

Pediculosis capitis (head lice) is a global health issue, particularly among school-aged children, caused by Pediculus humanus capitis. This condition can be transmitted both directly or indirectly via fomites. Symptoms commonly associated with Pediculosis capitis include itching of the scalp, sleep disturbances, and discomfort. Several factors generally influence the prevalence, including age, gender, frequency of hair washing, hair type, level of knowledge, personal hygiene, living conditions, and shared use of bedding or pillows. Research purposes to identify the risk factors associated with Pediculosis capitis among students at SDN Cawang 04 and SDN Cawang 12 in East Jakarta. This research is an analytical study with a cross-sectional approach. The research method employed is quantitative, utilizing questionnaires as research instruments and visual inspection to diagnose infestation, which is confirmed if eggs, nymphs, or adult lice are found in the hair. The sample was selected through random sampling from students in grades 3,4, and 5, with a total of 180 respondents determined using the Slovin formula. Data collection in this study used primary data collected through head lice or nit examinations and questionnaires. The research instruments used were a questionnaire regarding sociodemographic characteristics and questions to determine the number and risk factors for head lice. Data were analyzed using univariate analysis in SPSS. The results show that out of 180 respondents, 100 people (55.6%) were positive for Pediculosis capitis, with a higher infestation rate among female students (76, 42.2%) compared to male students (24, 13.3%). Based on respondent characteristics, the most common age was 9 years old, namely 39 people (21.6%), and grade IV, 37 people (20.5%). Dominant risk factors include age, gender, having long hair, a family size of more than four members, and parents' highest education level being high school. This study indicates that the incidence of Pediculosis capitis remains relatively high.
Morphology Profile and PD-L1 Expression in Non-Small Cell Lung Cancer (NSCLC) Patients Nurprilinda, Marliana; Novelyn, Silphia; Siahaan, Sonya Trinur Veronika; Angreni, Frisca
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.6167

Abstract

Lung cancer cases in Indonesia became the second highest with the highest mortality rate in 2022. Various advanced examinations such as histopathology and immunohistochemistry are performed to identify the morphological types of lung cancer. Histopathologically, lung cancer classified into two types are Non-Small Cell Lung Cancer (NSCLC) and Small Cell Lung Cancer (SCLC). After histopathological examination, further immunohistochemical testing is required to help classify the subtype and identify therapeutic markers. One of the markers is the expression of Programmed Death Ligand 1 (PD-L1). Patients with this marker can receive anti-PD-L1 immunotherapy according to the specified criteria. This study determined the morphological profile and PD-L1 expression in patients with Non-Small Cell Lung Cancer (NSCLC) at Siloam MRCCC Semanggi Hospital between 2020 and 2022. The method used was descriptive with a retrospective approach by collecting data from the archives of the Anatomical Pathology Laboratory at Siloam MRCCC Semanggi Hospital. The population in this study comprised all patients diagnosed with NSCLC who underwent PD-L1 IHC testing at Siloam MRCCC Semanggi Hospital between 2020 and 2022. Data collection was conducted using a total sampling method, including all individuals who met the predefined inclusion and exclusion criteria. The final sample consisted of 91 patients diagnosed with NSCLC who had undergone PD-L1 IHC examination during the 2020–2022 period. A total of 91 patients including the inclusion and exclusion criteria were included in the data and analyzed. The analysis revealed that the age group 60-69 years accounted for 39.5% of cases, 54.9% of cases were male, 73.6% of cases had an adenocarcinoma morphology, and 54.9% of cases had a negative PD-L1. The incidence of NSCLC patients who underwent PD-L1 IHK examination based on age was dominated by the 60-69 year age group, and most of them were male with the most common diagnosis being adenocarcinoma morphology type and PD-L1 expression with negative values.