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Yety Lindawati, Novena
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Optimasi Kapsul Bawang Putih (Allium sativum Linn) sebagai Terapi Alternatif Pengobatan TBC Yety Lindawati, Novena; Hartono
Jurnal Farmasi (Journal of Pharmacy) Vol. 2 No. 1 (2013): Jurnal Farmasi (Journal of Pharmacy), October 2013
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Garlic (Allium Sativum Linn) proven inhibiting the Mycobacterium tuberculosis propagation. Alisin compound which implied in garlic (Allium Sativum Linn) functioning as wide spectrum antimikroba capable to pursue Tuberkulosis cause by bacterium. Garlic Capsule (Allium Sativum Linn) have to fulfill conditions as according to Decree Of The Minister For Public Health of Republic Indonesia No: 661/MENKES/SK/VII/1994 about traditional medicines. The results shows that garlic extract with 240 µg/ml medium (equivalent by 600 mg garlic extract per capsule) has better potency in pursuing growth of Mycobacterium tuberculosis (taken a from pure breeding colony from patient sputum culture which suffering Tuberkulosis BTA type + 2, positive culture 9, resisten to rifampisin) compared to 320 and 400 µg / ml media.Dry extract of garlic (Allium Sativum Linn) fulfilling conditions upon which fill traditional drug capsule, for example total plate number 1.5 (qualifying at the most 10); mould and khamir number 6x102 (qualifying at the most 104); negative result of patogen bacteries such as coliform bacteries, Eschericia Coli, Salmonella Sp, and Staphylococcus aureus; negatife result of of aflatoxin (qualify at the most 30 bpj); total water content equal to 1 - 2 % (qualifying at the most 10 %). Dry garlic extract (Allium Sativum Linn) capsule fulfilling conditions of pharmaceutical form of traditional capsule result disintegration time less than 13 minute (qualify at the most 15 minute) and fulfill uniformity of weight which qualify for the traditional capsule
Pengembangan Formula Gel Ekstrak Teh Hijau (Camellia sinensis L.) sebagai Penyubur Rambut Yety Lindawati, Novena; Murtisiwi, Lusia; C.E. Dhurhania
Jurnal Farmasi (Journal of Pharmacy) Vol. 3 No. 1 (2014): Jurnal Farmasi (Journal of Pharmacy), October 2014
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Hair loss is can be a fashionable matter. Green tea extract which the concentration is about 5% can stimulate hair growing (Sumakdjaja, et.al.,2008). The compound in green tea extract are catecine and their derivate. They are epicatecine (EC), epicatecine galat (ECG), and epigalocatecine (EGCG). In green tea axtract there are also contains galat acid, galocatecine galat (GCG), galocatecine (GC), catecine galat (CG), catecine (C), vitamin B and vitamin C (Agus, 2007) which can make hair root stronger, prefent hair loss, to inhibit free radical, neutralize poisson, and protect head skin from infection. People more interest to use cosmetics and foods with green tea extract. There is no hair growth stimulating gel with green tea extract in the market. This is the reason of this research, is to develope hair growth stimulating gel formula. There are four formula in this research. They are formula I (Carbopol 1%, TEA0 3%, and glycerine 1%), formula II (CMC Na 3% and glycerine 1%), formula III (PEG 400 72%, PEG 4000 8%, and glycerine 1%) and formula IV (carbopol 0,75%, TEA 2%, PEG 400 12%, and glycerine 1%). The concentration of green tea axtract in each formula are 5%. In each formula contains 0,1% nipagin as a preservative, and 0,1% sodium metabisulfit. The quality of each gel formula tested by organoleptic test, homogenity test, pH test, spread test, thickening test, protection test, primary iritation test, aceptability test, and hair growth stimulating activity test.
EVALUASI POLA PERESEPAN & PENGARUH RASIONALITAS ANTIBIOTIK PROFILAKSIS TERHADAP KEJADIAN INFEKSI DAERAH OPERASI PADA PASIEN BEDAH ANAK : Evaluation of Prescribing Patterns & Influence of Rationality of Prophylactic Antibiotics on the Incidence of Surgical Site Infections in Pediatric Surgery Patients Yety Lindawati, Novena; Ramadhan, Taufiq
Jurnal Farmasi (Journal of Pharmacy) Vol. 14 No. 2 (2025): Jurnal Farmasi (Journal of Pharmacy), October 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/yg1g2073

Abstract

Infeksi daerah operasi (IDO) merupakan salah satu infeksi terkait pelayanan kesehatan yang paling banyak ditemukan, dengan insidensi mencapai satu dari 3 pasien yang menjalani operasi. Pemberian antibiotik perlu dilakukan secara rasional untuk memaksimalkan efikasi serta mencegah perkembangan resistensi antimikroba. Penelitian terkait IDO pada pasien bedah anak akan dapat membantu para pemangku kebijakan untuk menentukan langkah yang paling efektif dalam pencegahan IDO. Penelitian ini adalah penelitian observasional analitik dengan rancangan kohort retrospektif, yang melibatkan rekam medik pasien anak yang menjalani prosedur bedah invasif pada periode 1 Juli hingga 31 Desember 2023 di Rumah Sakit Ortopedi Prof. Dr. R. Soeharso Surakarta. Variabel yang diamati dalam penelitian ini adalah rasionalitas dari terapi antibiotik profilaksis yang diberikan kepada pasien bedah anak, dan luaran klinis berupa kejadian IDO. Rasionalitas antibiotik profilaksis dinilai dengan algoritma Gyssens, mengacu pada seri tatalaksana pencegahan IDO yang diterbitkan oleh POP-NeoPed Study Group dan tatalaksana antibiotik profilaksis oleh American Society of Health-System Pharmacists (ASHP). Luaran klinis berupa kejadian IDO ditentukan dengan kriteria yang disusun oleh CDC. Data dari 268 terapi antibiotik profilaksis pada pasien bedah anak, terdapat 33 terapi (12,31 %) yang masuk ke dalam kategori VI (data tidak lengkap), 94 terapi (35,07 %) yang masuk ke dalam kategori V (tidak ada indikasi pemberian antibiotik), 2 terapi (0,75 %) yang masuk ke dalam kategori IVd (ada antibiotik lain yang spektrumnya lebih sempit), 125 terapi (46,64 %) yang masuk ke dalam kategori IIa (tidak tepat dosis), dan 14 terapi (5,22 %) yang masuk ke dalam kategori I (tidak tepat waktu pemberian).
Co-Authors C.E. Dhurhania Hartono Hartono Murtisiwi, Lusia Ramadhan, Taufiq