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C.E. Dhurhania
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Pengembangan Formula Gel Ekstrak Teh Hijau (Camellia sinensis L.) sebagai Penyubur Rambut Yety Lindawati, Novena; Murtisiwi, Lusia; C.E. Dhurhania
Jurnal Farmasi (Journal of Pharmacy) Vol. 3 No. 1 (2014): Jurnal Farmasi (Journal of Pharmacy), October 2014
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Hair loss is can be a fashionable matter. Green tea extract which the concentration is about 5% can stimulate hair growing (Sumakdjaja, et.al.,2008). The compound in green tea extract are catecine and their derivate. They are epicatecine (EC), epicatecine galat (ECG), and epigalocatecine (EGCG). In green tea axtract there are also contains galat acid, galocatecine galat (GCG), galocatecine (GC), catecine galat (CG), catecine (C), vitamin B and vitamin C (Agus, 2007) which can make hair root stronger, prefent hair loss, to inhibit free radical, neutralize poisson, and protect head skin from infection. People more interest to use cosmetics and foods with green tea extract. There is no hair growth stimulating gel with green tea extract in the market. This is the reason of this research, is to develope hair growth stimulating gel formula. There are four formula in this research. They are formula I (Carbopol 1%, TEA0 3%, and glycerine 1%), formula II (CMC Na 3% and glycerine 1%), formula III (PEG 400 72%, PEG 4000 8%, and glycerine 1%) and formula IV (carbopol 0,75%, TEA 2%, PEG 400 12%, and glycerine 1%). The concentration of green tea axtract in each formula are 5%. In each formula contains 0,1% nipagin as a preservative, and 0,1% sodium metabisulfit. The quality of each gel formula tested by organoleptic test, homogenity test, pH test, spread test, thickening test, protection test, primary iritation test, aceptability test, and hair growth stimulating activity test.
Identifikasi Kualitatif Ekstrak, Fraksi n-Heksan, Fraksi Etil Asetat, Fraksi Air Herba Bandotan (Ageratum conyzoides L.) Ayu Palupi, Dwi; Pratimasari, Diah; C.E. Dhurhania
Jurnal Farmasi (Journal of Pharmacy) Vol. 14 No. 1 (2025): Jurnal Farmasi (Journal of Pharmacy), April 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/kk6rmd70

Abstract

Bandotan (Ageratum conyzoides L.) is a plant that grows in subtropical and tropical regions and has high growth and adaptability. Some studies have shown that Bandotan herb has good activity as an antibacterial, anti-inflammatory, antioxidant, and antidiabetic agent. Existing research is limited to the content and activity of Bandotan herb extracts. However, some extracts that undergo fractionation are known to enhance their activity. Therefore, this study aims to identify the flavonoid and phenolic compounds in the polar, semi-polar, and non-polar fractions of Bandotan herb. The research started with macerating the Bandotan herb using ethanol as a solvent and concentrating it to obtain a thick extract. This thick extract was then suspended in warm water and fractionated successively using n-hexane and ethyl acetate solvents. The extracts and fractions obtained were analyzed for their content using tube tests and Thin Layer Chromatography (TLC). The tube test results indicated that the extract, ethyl acetate fraction, and water fraction were positive for flavonoids, while the n-hexane fraction was negative for flavonoids. TLC results showed variations in the compound profiles among the extract and its different fractions.
Co-Authors Ayu Palupi, Dwi Murtisiwi, Lusia Pratimasari, Diah Yety Lindawati, Novena