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All Journal Jurnal EduHealth Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran Indonesian Journal of Pharmacology and Therapy
Andra Novitasari
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Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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Faktor-faktor yang Berhubungan dengan Kejadian Systemic Inflammatory Response Syndrome pada Pasien Hemodialisis Zulva Safiira; Zulfachmi Wahab; Dyah Mustika; Andra Novitasari
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 2 No. 4 (2024): Oktober : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v2i4.4333

Abstract

Background: Chronic kidney failure (CKD) is a condition of decreased kidney function for more than three months. Patients of CKD require renal replacement therapy by hemodialysis. Patients of hemodialysis often associated with Systemic Inflammatory Response Syndrome (SIRS) incidence and infection is one of the risks. Infection can develop into a dangerous event, namely sepsis. In Indonesia there were 433 cases of sepsis lead to death in hemodialysis patients. This study aims to analyze the risk facotrs that cause SIRS incidence in RS Roemani Muhammadiyah Semarang. Method: This was an observational analytic study with cross sectional design. Vascular access, age, sex, nutritional status, diabetes mellitus, hypoalbuminemia, anemia as independent variable and SIRS incidence as dependent variable. The subject in this study were all patients with a diagnosis of CKD who undergo hemodialysis treatment. This study was carried out in RS Roemani Muhammadiyah Semarang. The sampling was taken by total sampling through medical record data sources during the period January 2017 until December 20121. Statistical analysis used the Chi-Square Test for bivariat analysis and logistic regression test for multivariate.Result: Total sample obtained 46 samples. Result of bivariate test indicate that the vascular access (p=0,012); age (p=0,245); sex (p=0,332); nutritional status (p=0,457); diabetes mellitus (p=0,013); hypoalbuminemia (p=0,009); anemia (p=0,049). The Results of multivariate are known to have a strong influence on the incidence of SIRS are diabetes mellitus (p=0,035, OR=14,360) dan hypoalbuminemia (p=0,021, OR=10,167).Conclusion: There were significant correlation between vascular access, diabetes mellitus, hypoalbuminemia, anemia and SIRS incidence on hemodialysis patients. The Results of multivariate analysis showed that diabetes mellitus and hypoalbuminemia is very influential with SIRS incidence on hemodialysis patients in RS Roemani Muhammadiyah Semarang.
Correlation of Age, Gender, and Body Mass Index With NLR of Covid-19 Patients Novianti, Novianti; Andra Novitasari; Ika Dyah Kurniati
Jurnal EduHealth Vol. 16 No. 01 (2025): Jurnal EduHealt, Edition January - March, 2025
Publisher : Sean Institute

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Abstract

The inflammatory and immunological responses may be used to predict the outcome of COVID-19 patients. The NLR may be used as an indicator of the severity of systemic inflammation in patients with viral pneumonia (NLR). NLR is linked to age-related immunosenescence Sex , and NLR, is a hormonally mediated trait. The prevalence of NLR is higher in people with COVID-19 who are overweight or obese. The researchers wanted to see how factors including age, gender, and BMI affected the NLR of people with COVID-19. This researched used Cross Sectional approach. A sample of 70 respondents with COVID-19 confirmed through RT-PCR examination at Dedy Jaya Hospital Brebes period January-August 2022. Statistical analysis to determine the correlation between variables using Spearman's non-parametric.  From 70 samples of COVID-19 patients , the results of the analysis showed that the correlation between NLR and age had ap value = 0.001 with r = 0.558, the correlation between NLR and gender had ap value = 0.001 with r = 0.461 .
Perbandingan Pengajaran Menggunakan Keterampilan Klinis Video Dengan Keterampilan Klinis Konvensional Aulia Lukito Wardhani; Andra Novitasari; Mega Pandu Arfiyanti
Vitalitas Medis : Jurnal Kesehatan dan Kedokteran Vol. 2 No. 2 (2025): Vitalitas Medis : Jurnal Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/vimed.v2i2.1450

Abstract

The use of video media in clinical skills education has been implemented at the Faculty of Medicine, Universitas Muhammadiyah Semarang (UNIMUS) since 2019, particularly to enhance students’ understanding and skills in neuromotor physical examination. This study aimed to evaluate the effectiveness of video-based teaching compared to conventional methods in clinical skills learning. A quantitative descriptive method with univariate analysis was used on 138 students who met the inclusion and exclusion criteria. Data were collected from Objective Structured Clinical Examination (OSCE) scores and analyzed using a total sampling technique. The results showed that students who received video-based learning had significantly higher average OSCE scores (93.33 ± 8.918 SD in Block 1) than those who were taught without video media (68.12 ± 15.58 SD in Block 3). In Block 1, 98.6% of the students achieved the “excellent” score category, while only 26.1% of students in Block 3 reached the same level. These findings indicate that the use of teaching videos significantly improves students’ clinical skills and helps overcome the limitations of conventional methods, which tend to promote passive learning. Therefore, the implementation of video-based teaching media can be an effective method to improve the quality of clinical skills education, encourage active student participation, and support the achievement of optimal competencies in medical education. This approach not only enhances skill acquisition but also contributes to more engaging and student-centered learning experiences in the clinical education environment.
Effect of essential oil of black cumin (Nigella sativa) on hematological profiles and total cholesterol levels of Wistar rats exposed by cigarette smoke Rakhmawatie, Maya Dian; Muhammad Adzanta Al Afghani; Nurkomariah Zulhijjah; Andra Novitasari; Arief Tajally Adhiatma
Indonesian Journal of Pharmacology and Therapy Vol 1 No 1 (2020)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.495

Abstract

Cigarette smoke contains toxic substances such as carbon monoxide, lead, cadmium, tar and hydrogen cyanide which can triggeroxidative stress and causeerythrocyte membrane damage and hemoglobin oxidation. In addition, it also contains nicotine which can increase the total cholesterol levels. Black cumin containing thymoquinone has been known for its antioxidant and anticholesterol activities. This study aimed to investigate the effect of black cumin extract on hematological profiles and total cholesterol levels of Wistar rats exposed by cigarette smoke. It was an experimental study with randomized posttest only control group design. Twenty Wistar rats (Rattus norvegicus) that divided into four groups were used in this study.The normal control group (N) was provided with standard feed,the negative control group (C) was exposed to the cigarette smoke with two pieces of cigarettes/day for 14 days, the treated groups were given black cumin extract 200mg/kg (T1) and 400mg/kg (T2) and exposed by cigarette smoke two pieces of cigarettes/day for 14 days. On day 15, blood samples from the rats were taken through the sinus orbitalis and then the erythrocyte, the hemoglobin and the total cholesterol levels were examined. Data were analyzed using the one-way ANOVA test and continued by the post-hoc test. The results showed the number of erythrocytes and hemoglobin levels of the T2 group was significantly higher than those of the C group (p<0.05). Although, total cholesterol levels of the T2 group was lower than that of other groups, however it was not significantly different (p>0.05). In conclusion, the administration of black cumin extract at 400mg/kg significantly increases the erythrocytes numbers and the hemoglobin levels in Wistar rats exposed by cigarette smoke.
Co-Authors Arief Tajally Adhiatma Aulia Lukito Wardhani Dyah Mustika Ika Dyah Kurniati Maya Dian Rakhmawatie Mega Pandu Arfiyanti Muhammad Adzanta Al Afghani Novianti Novianti Nurkomariah Zulhijjah Zulfachmi Wahab Zulva Safiira