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All Journal PROSIDING SEMINAR NASIONAL Jurnal Kedokteran Muhammadiyah Indonesian Journal of Pharmacology and Therapy
Arief Tajally Adhiatma
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Education Immunology & microbiology Medicine & Pharmacology

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Analisis Faktor-Faktor yang Berhubungan dengan Kejadian Gagal Ginjal Kronik Pada Pasien Hemodialisis Di RSUD Tugurejo Semarang Arief Tajally Adhiatma; Zulfachmi Wahab; Ibnu Fajar Eka Widyantara
Jurnal Kedokteran Muhammadiyah Vol 5, No 2 (2016): JURNAL KEDOKTERAN
Publisher : Jurnal Kedokteran Muhammadiyah

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Abstract

Latar Belakang: Gagal ginjal kronik adalah gangguan fungsi ginjal yang bersifat progesif dan irreversibel. Gangguan fungsi ginjal initerjadi ketika tubuh gagal untuk mempertahankan metabolisme dan keseimbangan cairan dan elektrolit. Faktor-faktor risiko sepertihipertensi, diabetes melitus, nefropati obstruksi, dan pielonefritis kronik dapat menyebabkan terjadinya gagal ginjal kronik. Penelitian inibertujuan untuk menganalisis faktor-faktor yang berhubungan dengan kejadian gagal ginjal kronik pada pasien hemodialisis di RSUDTugurejo Semarang.Metode: Penelitian ini merupakan studi deskriptif analitik dengan pendekatan retrospektif yang dianalisis dengan uji statistik dengan tingkatkemaknaan 95% yang meliputi analisis univariat, bivariat dan multivariat pada pasien hemodialisis. Sampel diambil dari rekam medis padaperiode Januari-Desember 2014 dengan teknik Simple Random Sampling.Hasil: Hasil analisis bivariat variabel hipertensi, diabetes melitus, nefropati obstruksi dan pielonefritis kronik menunjukan ada hubungandengan kejadian gagal ginjal kronik. Hasil analisis multivariat menunjukan hipertensi merupakan variabel paling berpengaruh terhadapkejadian gagal ginjal kronik (OR=5,652; p=0,023).Kesimpulan: Hipertensi merupakan faktor risiko yang paling berpengaruh terhadap kejadian gagal ginjal kronikKata kunci : Gagal ginjal kronik, Faktor risiko
PENDAMPINGAN KELAS IBU HAMIL DI KELURAHAN BANDARHARJO DAN KELURAHAN DADAPSARI, SEMARANG Indri Astuti Purwanti; Nuke Devi Indrawati; Arief Tajally Adhiatma
PROSIDING SEMINAR NASIONAL & INTERNASIONAL 2017: Prosiding Seminar Nasional Publikasi Hasil-Hasil Penelitian dan Pengabdian Masyarakat
Publisher : Universitas Muhammadiyah Semarang

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Abstract

Background. The city of Semarang was ranked third highest in terms of the number of maternal mortality cases in 2015. The work area of Bandarharjo Puskesmas has the highest number of deaths among other areas in Semarang City and all pregnant women in this region were classified as high risk during the year. The cause is indifference to pregnancy examination. This is indicated by the low attendance of pregnant class. Objective. The purpose of this activity is to increase the presence of pregnant classes and to increase awareness of pregnancy and high risk pregnancy outcomes. Method. The method used is the empowerment and mentoring of partners, as well as health education for pregnant women (target). Results. The attendance and care of the pregnant class of Bandarharjo Urban Village is still ongoing while the Dadapsari Village has increased.Keywords: class of pregnant women, concern for pregnancy examination.
The Urgency of Pregnancy Risk Factors Booklet Indri Astuti Purwanti; Nuke Devi Indrawati; Arief Tajally Adhiatma
PROSIDING SEMINAR NASIONAL & INTERNASIONAL 2017: Proceeding 3rd ISET 2017 | International Seminar on Educational Technology 3rd 2017
Publisher : Universitas Muhammadiyah Semarang

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Abstract

Maternal mortality cases in Semarang city were still high in 2015. Among all district in Semarang city, work area of Puskesmas Bandarharjo had the most maternal mortality cases. All pregnant women there had not beenrealized their risk pregnancy factors. Hence, they need health education about pregnancy risk factors to changetheir mindset. The right media in health education is booklet because it is written, can be colorful, can containpictures to explain the information and not limited by pages. It also can influence behavior intention of thepregnant woman, her husband, her parents, her parents in law and other people who read the book to detect earlypregnancy risk factors.Keywords: maternal mortality, pregnancy risk factors, media health education.
Effect of essential oil of black cumin (Nigella sativa) on hematological profiles and total cholesterol levels of Wistar rats exposed by cigarette smoke Rakhmawatie, Maya Dian; Muhammad Adzanta Al Afghani; Nurkomariah Zulhijjah; Andra Novitasari; Arief Tajally Adhiatma
Indonesian Journal of Pharmacology and Therapy Vol 1 No 1 (2020)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.495

Abstract

Cigarette smoke contains toxic substances such as carbon monoxide, lead, cadmium, tar and hydrogen cyanide which can triggeroxidative stress and causeerythrocyte membrane damage and hemoglobin oxidation. In addition, it also contains nicotine which can increase the total cholesterol levels. Black cumin containing thymoquinone has been known for its antioxidant and anticholesterol activities. This study aimed to investigate the effect of black cumin extract on hematological profiles and total cholesterol levels of Wistar rats exposed by cigarette smoke. It was an experimental study with randomized posttest only control group design. Twenty Wistar rats (Rattus norvegicus) that divided into four groups were used in this study.The normal control group (N) was provided with standard feed,the negative control group (C) was exposed to the cigarette smoke with two pieces of cigarettes/day for 14 days, the treated groups were given black cumin extract 200mg/kg (T1) and 400mg/kg (T2) and exposed by cigarette smoke two pieces of cigarettes/day for 14 days. On day 15, blood samples from the rats were taken through the sinus orbitalis and then the erythrocyte, the hemoglobin and the total cholesterol levels were examined. Data were analyzed using the one-way ANOVA test and continued by the post-hoc test. The results showed the number of erythrocytes and hemoglobin levels of the T2 group was significantly higher than those of the C group (p<0.05). Although, total cholesterol levels of the T2 group was lower than that of other groups, however it was not significantly different (p>0.05). In conclusion, the administration of black cumin extract at 400mg/kg significantly increases the erythrocytes numbers and the hemoglobin levels in Wistar rats exposed by cigarette smoke.
Co-Authors Andra Novitasari Ibnu Fajar Eka Widyantara Indri Astuti Purwanti Maya Dian Rakhmawatie Muhammad Adzanta Al Afghani Nuke Devi Indrawati Nurkomariah Zulhijjah Zulfachmi Wahab