Article Per Year (5 Year)
p-Index From 2020 - 2025
0.408
P-Index
This Author published in this journals
All Journal Hydrogen: Jurnal Kependidikan Kimia Bioscientist : Jurnal Ilmiah Biologi
Mujaddid, Jamilul
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Immunology & microbiology Social Sciences

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Uji Aktivitas Antibakteri Ekstrak Daun Bridelia micranth Lombok pada Escherichia coli Bayani, Faizul; Sudiana, Endang; Hamdani, Ade Sukma; Wahyuni, Ida; Mujaddid, Jamilul; Hulyadi, Hulyadi
Bioscientist : Jurnal Ilmiah Biologi Vol. 11 No. 2 (2023): December
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v11i2.9931

Abstract

The aim of this research is to identify the antibacterial activity of Bridelia micranth Lombok extract on the pathogenic bacteria Escherichia coli. The independent variable in this study was the concentration of Bridelia micrantha leaf extract. The concentration of Bridelia micrantha leaf extract in this study was varied from 20%, 40%, 60%, and 80%. The dependent variable is the ability of Bridelia micrantha leaf extract as an antibacterial. The antibacterial ability of Bridelia micrantha leaf extract was measured based on the diameter of the clear zone with three repetitions. As a comparison, an antibacterial is used, namely amoxicillin. Data analysis in this research was carried out descriptively, and then non-parametric tests were carried out to test the homogeneity of the data. In this study, the antibacterial ability of Bridelia micrantha leaf extract was discovered. At a concentration of 20%, the average diameter of the inhibitory zone was 2.5 mm which was categorized as none (resistance), 40% concentration was 9.83 mm in the non-existent category (resistance), 60% concentration was 13.66 in the weak category (intermediate), and at a concentration of 80% 16.5 mm is in the medium (sensitive) category. The research results indicated that Bridelia micrantha leaf extract had antibacterial activity against Escherichia coli bacteria. When compared with amoxicillin, the ability of Bridelia micrantha leaf extract as an antibacterial is still lower. Amoxicillin was able to inhibit the growth of Escherichia coli by 18.13 mm, while the highest ability of Bridelia micrantha leaf extract was 16.5 mm. Based on Ministry of Health regulations, antibacterials can be used if the inhibition zone is between 14-18 mm. So, Bridelia micrantha leaf extract can be used as an antibacterial, but it needs to be tested further before being applied to the public.
Identification of Secondary Metabolite Compounds from Melandean (Bridelian micrantha) Leaf Extract Bayani, Faizul; Kurniasari, Baiq Anting; Hamdani, Ade Sukma; Yuliana, Depi; Wahyuni, Ida; Mujaddid, Jamilul
Hydrogen: Jurnal Kependidikan Kimia Vol. 11 No. 6 (2023): December 2023
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v11i6.9879

Abstract

The Melandean plant or Bridelia micrantha (Hochst.) Baill is traditionally used by the community to treat various human diseases, such as poisoning, paralysis, digestive diseases, diabetes, syphilis, and other diseases. Bridelia micrantha is believed to have active chemical compounds in the form of secondary metabolites which are useful for treatment. This active chemical compound is contained in the roots, leaves, seeds, skin, stems, and fruit. Bridelia micrantha leaves were used as samples in this study to analyze the secondary metabolite compounds contained therein. Leaf extraction was carried out using 80% methanol solvent through a maceration process. Analysis was carried out qualitatively using the phytochemical screening test method and quantitatively using the thin layer chromatography test method. Based on the results of the phytochemical screening test carried out, it is known that Bridelia micrantha is positive for containing active compounds in the form of flavonoids, tannins, saponins, and alkaloids. The results of the thin layer chromatography (TLC) test showed that flavonoid compounds were found with an Rf value of 0.437, tannin compounds with an Rf value of 0.312, saponin compounds with an Rf value of 0.625, and alkaloid compounds with Rf values of 0.125, 0.187, 0.312 and 0.5.
Co-Authors Bayani, Faizul Hamdani, Ade Sukma Hulyadi, Hulyadi Ida Wahyuni Kurniasari, Baiq Anting Sudiana, Endang Yuliana, Depi