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All Journal Indonesian Journal of Pharmaceutical Science and Technology Chemistry Indonesian Journal of Chemical Research Jurnal Empathy Pengabdian Kepada Masyarakat
Hardy, Junius
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Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Education Engineering Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health

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Analysis of Hydroquinone in Face Whitening Cream by UV-Vis Spectrophotometry and GC-MS Spectrometry Karnelasatri, Karnelasatri; Tahya, Candra Yulius; Adila, Mahda Uli; Hardy, Junius; Munthe, Sri Wahyu Ningsih
Indonesian Journal of Chemical Research Vol 11 No 3 (2024): Edition for January 2024
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2024.11-kar

Abstract

The analytical method to determine the compound content in both food and cosmetic products must be carried out carefully to ensure the validity of the analysis results. Hydroquinone has been widely found to be used as an active whitening agent in whitening cream. Technological advances have led to illegal whitening creams becoming more accessible online. This study aims to examine the hydroquinone content in the whitening samples cream purchased from e-commerce by various analytical methods, such as FeCl3 reagent, cerimetric titration, UV-Vis spectrophotometry, and GC-MS spectrometer compared to the positive control hydroquinone. The results of the hydroquinone content by cerimetric titration and UV-Vis spectrophotometry methods were calculated quantitatively. Furthermore, the result compared through statistical tests showed a consistent hydroquinone content for both methods. Contrariwise, the GC-MS method showed negative results due to differences in the extraction process and solvent solubility. Based on the result obtained, can be concluded that all samples of whitening cream did not meet the requirements of BPOM No. 23 of 2019.
Antioxidant Activity of Extract Combination from Moringa oleifera Leaves and Garcinia mangostana L. Pericarp Hartanti, Yesiska Kristina; Lukas, Diksa T.; Hardy, Junius
Indonesian Journal of Pharmaceutical Science and Technology Vol 12 (2025): Vol. 12 Suppl. 2 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i0.59284

Abstract

Radical-related diseases can be mitigated through natural antioxidant therapies that help regulate the formation and accumulation of free radicals. The pericarp of Garcinia mangostana L. and the leaves of Moringa oleifera are well-known for their antioxidant properties due to their high level of bioactive compounds, such as flavonoids, phenolics, and xanthones. This study aimed to explore the antioxidant capabilities of these two herbal extract combinations. Using the maceration method with 96% ethanol, the extraction yields were 11.4% w/w for M. oleifera and 24.11% w/w for G. mangostana. Qualitative phytochemical screening revealed differences in secondary metabolites, particularly steroids and triterpenes, between the two extracts. The antioxidant activity was categorized based on EC50 values, with crude G. mangostana showing very strong activity (<50 µg/mL) and M. oleifera classified as strong (50–100 µg/mL). Combinations of the extracts (2–10 ppm) produced very strong antioxidant activity but showed reduced efficacy compared to G. mangostana alone, suggesting antagonistic interactions based on combination index (IC) calculation. This study emphasizes the need for multiple antioxidant assays to evaluate diverse mechanisms and recommends further research to optimize synergistic effects in herbal extract combinations.
Edukasi Pemanfaatan TOGA dan Pembuatan Produk Disinfektan serta Balsam Stik Berbahan Dasar Lengkuas Ayuningtyas, Nurista Dida; Hardy, Junius; Pramitaningastuti, Anastasia S; Arianditha Pranasti, Ernestine; Reni Cyrena Santoso, Feronia; Setiawan, Benny
Jurnal Empathy Pengabdian Kepada Masyarakat Jurnal Empathy Pengabdian Kepada Masyarakat Volume 5 Nomor 1 Tahun 2024
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/jurnalempathy.v5i1.195

Abstract

Background: Batok Village has quite a large agricultural land with the commodity of agricultural products, Alpinia galanga, but the selling value of Alpinia galanga is very cheap. Therefore, the community service team aims to provide education on planting TOGA and making disinfected products and balsam sticks to increase their market value. Methods: Steps taken are observation, preparation, implementation, and evaluation. Results: In the observation, it was observed that Batok Village has agricultural land that is fertile enough for TOGA planting. The preparation process carried out is the manufacture of disinfectant products and balsam sticks with Alpinia galanga as the active ingredient. The Alpinia galanga disinfectant is shown to inhibit the growth of microorganisms, and the resulting balsam stick is solid, easy to apply, produces a warm effect, and does not irritate. Conclusion: The participants were very enthusiastic in participating in the PkM activities, and the results of the evaluation analysis of the participants' knowledge level increased.
Co-Authors Adila, Mahda Uli Arianditha Pranasti, Ernestine Ayuningtyas, Nurista Dida Benny Setiawan, Benny Hartanti, Yesiska Kristina Karnelasatri, . Lukas, Diksa T. Munthe, Sri Wahyu Ningsih Pramitaningastuti, Anastasia S Reni Cyrena Santoso, Feronia Tahya, Candra Yulius