Kamajaya, I Gusti Ngurah Agung Trisnu
Unknown Affiliation

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

Relationship between total 25(OH)D and interleukin-2 contents in preterm conversion patients Sanjaya, I Nyoman Hariyasa; Mulyana, Ryan Saktika; Kamajaya, I Gusti Ngurah Agung Trisnu
Indonesian Journal of Perinatology Vol. 5 No. 1 (2024): Available online: 1 June 2024
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/inajperinatol.v5i1.37

Abstract

The most essential nutrient for pregnant women is vitamin D. A lack of vitamin D can cause preterm labor and other issues like low birth weight, preeclampsia, and issues with the baby's bones. According to some research, there is no safe top level and a 75–80 nmol/L range. According to additional studies, an ideal range is between 75 and 110 nmol/L and a daily dosage of 1800 to 4000 IU of vitamin D3. In both early and late pregnancies, women with sufficient vitamin D levels (at least 30 ng/mL) exhibited a significant decrease in the incidence of preeclampsia. It is also known that vitamin D modulates the immune system in several ways. T-cell proliferation can be suppressed, and pro-inflammatory cytokines, including IL-2, IFN-, and IL-17, can be produced less frequently when vitamin D is present. A lack of vitamin D may lead to a rise in cytokines that promote inflammation, such as IL-2. This paper will, therefore, examine the relationship between vitamin D, IL-2 levels, and the risk of premature labor.
The Outcome of Ethanol Directed Sclerotherapy for the Management of Endometrioma: A Systematic Review Kamajaya, I Gusti Ngurah Agung Trisnu; Suardika, Anom; Mahayasa, Putu Doster; Budiana, Nyoman Gede; Abhimantra, Gede Bagus Kantwa
Indonesian Journal of Perinatology Vol. 5 No. 2 (2024): (Available online: 1 December 2024)
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/inajperinatol.v5i2.56

Abstract

Background and Objectives: Ovarian endometriomas, commonly known as chocolate cysts, are prevalent gynecological conditions associated with chronic pelvic pain and infertility. Current standard treatment, laparoscopic cystectomy, poses risks such as reduced ovarian reserve. Ethanol-directed sclerotherapy has emerged as a minimally invasive alternative aiming to preserve ovarian tissue while treating endometriomas. This systematic review evaluates the outcome of ethanol directed sclerotherapy for the management of endometrioma. Methods: Following PRISMA guidelines, databases including PubMed, EMBASE, and Cochrane were searched in January 2024 using “endometrioma and sclerotherapy.” Inclusion criteria encompassed studies reporting success rate (SR), RR, and pregnancy rate (PR) post-treatment. Nine studies involving 499 patients were analyzed. Results: Ethanol sclerotherapy demonstrated >80% SR in six studies and <30% RR in seven studies, indicating efficacy in reducing recurrence. However, its impact on ovarian reserve remains inconclusive. Pregnancy outcomes were inconsistently reported, with one study achieving 100% PR, while others ranged from 0% to >30%. Variability in techniques, such as ethanol concentration and retention time, likely influenced outcomes. Conclusions: Ethanol sclerotherapy offers a promising alternative to surgery, showing lower RR and potential preservation of ovarian function. Despite these benefits, inconsistencies in procedural protocols and limited data on long-term fertility outcomes necessitate further research. Standardized guidelines and larger cohort studies are essential to establish sclerotherapy's role in endometrioma management, especially for fertility preservation.
Operative treatment for adenomyosis: update on literature review Winata, Gde Sastra; Suardika, Anom; Mahayasa, Putu Doster; Budiana, Nyoman Gede; Kamajaya, I Gusti Ngurah Agung Trisnu
Indonesian Journal of Perinatology Vol. 5 No. 2 (2024): (Available online: 1 December 2024)
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/inajperinatol.v5i2.58

Abstract

Adenomyosis, a condition characterized by the presence of endometrial tissue within the myometrium, poses significant challenges in diagnosis and management due to its widespread and infiltrative nature. Operative treatment remains the primary treatment of choice for patients with symptomatic adenomyosis, especially those seeking fertility preservation or uterine conservation. This review explores the latest surgical techniques, emphasizing the balance between effective lesion removal and preservation of uterine function. Techniques such as asymmetric dissection, wedge resection, and various flap methods are discussed, highlighting their role in minimizing the loss of healthy myometrium while preserving uterine integrity. The evolution of laparoscopic and robotic approaches has improved accuracy and recovery, while innovative procedures such as the PUSH operation offer improved structural healing after excision. The choice of technique is guided by preoperative imaging and intraoperative findings, tailored to the extent and location of adenomyosis involvement. This review underscores the importance of individualized surgical strategy in achieving optimal outcomes in the surgical management of adenomyosis.
Role of hypogastric artery ligation in obstetric and gynecological hemorrhage: narrative review Winata, Gde Sastra Winata; Suardika, Anom; Mahayasa, Putu Doster; Budiana, Nyoman Gede; Kamajaya, I Gusti Ngurah Agung Trisnu
Indonesian Journal of Perinatology Vol. 5 No. 2 (2024): (Available online: 1 December 2024)
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/inajperinatol.v5i2.59

Abstract

Hypogastric artery ligation (HAL) is a vital surgical intervention for controlling severe pelvic hemorrhage in obstetric and gynecological cases. This narrative review examines the efficacy, safety, and implications of HAL in managing life-threatening hemorrhages, including postpartum hemorrhage (PPH) and gynecological emergencies. HAL is particularly effective in addressing hemorrhage associated with uterine atony, placenta accreta spectrum disorders, and secondary bleeding following hysterectomy or gynecological surgeries. Success rates vary widely, ranging from 33.3% to 89.2%, depending on the indication and clinical scenario. HAL offers significant advantages in fertility preservation, especially in cases where uterine conservation is desired. The procedure has been shown to reduce arterial pulse pressure by 85% and overall blood flow by nearly 50%, enabling effective hemostasis. Despite these benefits, the success of HAL heavily depends on the surgeon's expertise and the timely identification of hemorrhage. While complications such as organ ischemia and collateral vessel injury are rare, their potential underscores the need for meticulous surgical technique and postoperative monitoring. The search strategy for this review included PubMed databases, focusing on articles published up to 2019 with keywords such as "Hypogastric Ligation," "hypogastric ligation gynecology," and "hypogastric ligation obstetric." A total of 262 studies were initially identified, with 8 meeting the inclusion criteria for detailed analysis. These studies highlight HAL's role as a fertility-sparing, cost-effective option for managing severe pelvic hemorrhage, making it an indispensable tool in obstetric and gynecological practice.