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Medication Adherence of Tamoxifen to Breast Cancer Patients and the Affecting’s Factors in Dharmais Cancer Hospital Jakarta Halilintar, Via Dolorosa; Nadjib, Mardiati; Andalusia, Lucia Rizka
JMMR (Jurnal Medicoeticolegal dan Manajemen Rumah Sakit) Vol 9, No 2 (2020): August
Publisher : Universitas Muhammadiyah Yogyakarta in Clollaboration with ADMMIRASI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jmmr.92120

Abstract

Several previous studies show that adherence to hormonal therapy increases the survival rate in Breast Cancer (BC) with ER+ or PR+. Tamoxifen is one of oral chemotherapy which is the most used hormonal therapy in breast cancer treatment regimens. The focus of the study was to determine the level of adherence and factors influencing the adherence of the treatment of BC patients undergoing hormonal therapy with Tamoxifen in patients at Dharmais Cancer Hospital in the year 2018. The study is an observational study with a cross-sectional design. The study was followed by 109 respondents. Medication adherence levels assessed via questionnaire modified MARS-5. Sociodemographic and clinical characteristics obtained from interviews using structured questionnaires. Medication adherence’s level of Tamoxifen was 90.9% with the proportion of adhering patients was 75.2% (82 of 109 patients). Multivariate analysis showed that the age of respondents, level of education, level of knowledge is the most influential factor and determine the level of treatment adherence. Education level is the variable that has the greatest effect on medication adherence. Through this study, it is recommended to pay more attention to patients with specific characteristics such as patients with low education and or low income.
Self-Medication and Outpatient Care Utilization after Implementation of National Health Insurance in Indonesia Halilintar, Via Dolorosa; Sjaaf, Amal Chalik
JMMR (Jurnal Medicoeticolegal dan Manajemen Rumah Sakit) Vol 8, No 2 (2019): August
Publisher : Universitas Muhammadiyah Yogyakarta in Clollaboration with ADMMIRASI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jmmr.8291

Abstract

The implementation of National Health Insurance in 2014 is expected to increase access in health services while reducing the economic burden due to illness. This study aims to see how the behavior of people in choosing treatment when experiencing health problems, whether they tend to select self-medication or outpatient treatment. Quantitative analysis was carried out on variables previously formed based on the KOR Data questionnaire found in SUSENAS 2017. The results of the study showed that more respondents chose to do self-medication than those who accessed formal services with outpatient care. Multivariate tests show all variables except secondary education significantly influence individual decisions to self-medication.
Faktor Determinan yang Memengaruhi Perilaku Swadiagnosis dan Swamedikasi pada Mahasiswa Kedokteran dan Non-Kedokteran Lonah, Lonah; Halilintar, Via Dolorosa; Lauwly, Edlyn Edrea
Jurnal Kesehatan Vol 14 No 1 (2023): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v14i1.3328

Abstract

Self-diagnosis and self-medication are some of the global health phenomena. Inappropriate behavior may lead to harmful effects such as misdiagnosis, antibiotic resistance, etc. Determinant factors such as age, gender, ownership of health insurance, and others are influencing self-medication. This study aims to find the prevalence of self-diagnosis and self-medication and the determinant factors influencing self-medication in university students. This study used a cross-sectional method conducted in April 2021 online. Using consecutive non-probability sampling, the research sample successfully obtained was 184 medical and non-medical faculty students. The research data were analyzed in univariate and bivariate. The prevalence of self-diagnosis and self-medication was 64.1% and 46.7% in the medical faculty-student group, then 63.0% and 43.5% in the non-medical faculty-student group. Duration of illness in the medical faculty-student group, self-diagnosis, and support from other persons in both groups of respondents significantly correlated with self-medication (p-value
ECONOMIC EVALUATION OF PHARMACOGENETIC-GUIDED PRESCRIBING IN PRECISION MEDICINE FOR CARDIOVASCULAR DISEASES: AN EVIDENCE SYNTHESIS FROM ASIAN COUNTRIES Halilintar, Via Dolorosa; Lonah, Lonah; Pujiyanto, Pujiyanto
Jurnal Manajemen Kesehatan Indonesia Vol 12, No 3 (2024): Desember 2024
Publisher : Magister Kesehatan Masyarakat, Fakultas Kesehatan Masyarakat, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jmki.12.3.2024.252-265

Abstract

Precision medicine, particularly pharmacogenetic-guided approaches, has emerged as a promising tool to optimize treatment strategies for cardiovascular disease. However, the economic evaluation of these approaches in Asian populations remains underexplored. This review study aimed to synthesize evidence on the implementation, methodology, research gaps, and limitations of pharmacogenetic-guided precision medicine in cardiovascular disease among the Asian population. A comprehensive search of electronic databases (Pubmed, Embase, Google Scholar and Cochrane Library) was conducted to identify relevant studies. The data were extracted and synthesized to address the study objectives A total of 12 studies were included in the analysis. Economic evaluation studies of pharmacogenetic-guided precision medicine in cardiovascular disease management in Asian countries are still limited, with precision medicine interventions often requiring high resources. The sampling process remains a challenge in conducting economic evaluation studies, and there are limitations in obtaining clinical outcome descriptions from real-world evidence, as most studies rely on literature reviews or modeling-based approaches. Furthermore, most studies use a provider or healthcare cost perspective, limiting the comprehensiveness of cost information. This evidence synthesis highlights the potential for pharmacogenetic-guided precision medicine in cardiovascular disease management among the Asian population, as well as the current challenges and limitations in conducting economic evaluations. Further research is needed to address these issues, develop more robust sampling strategies, obtain real-world clinical outcome data, and provide comprehensive cost information to inform clinical practice and healthcare policy in the region.