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A nutrition intervention study’s effect to hematology profiles on elderly group in social retirement home Sudargo, Toto; Suryani, Dyah; Widyaningrum, Rachmawati; Prameswari, Atika Anif; Aulia, Bianda; Sumayyah, Sumayyah; Setyawening, Annisa Luthfia; Putri, Sheila Rosmala
International Journal of Public Health Science (IJPHS) Vol 13, No 2: June 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i2.23290

Abstract

The increase in the elderly brings consequences, including a higher risk of disease. Inappropriate nutritional intake is also known as one of the risk factors related to the elderly's non-communicable diseases, and nutritional intervention is essential to improve the elderly nutritional status and quality of life. It was an interventional study with a before-after one-group approach. The study was conducted for three months (October-December 2021) in three social retirement homes. The intervention given was supplementation with additional protein sources and snacks each day. The biochemistry profiles were taken 2 times: before and after three months of intervention, comprised of HbA1c, lipid, transferrin, creatinine, and blood pressure level. The data will be analyzed for its normality before being processed with paired t-test or Wilcoxon signed rank based on the normality results. The analysis results show that there are significantly lower transferrin levels (p=0.040), an increase in cholesterol level (p=0.000), and low-density lipoprotein (LDL) level increased from 114.05±32.03 to 125.94±31.41 (p=0.000). There is also a remarkable decrease in hemoglobin (p=0.005) and high-density lipoprotein (HDL) levels. Conversely, there are an increase in HbA1C (p=0.007) and triglyceride level (p=0.005). There is no significant difference in creatinine level. We conclude that nutrition interventions have a significant effect on elderly blood profiles. However, to achieve an improvement, the study should consider physical activity and other variables that might be altering the results.
MATERNAL GUT MICROBIOME AND ITS IMPACT ON FETAL OUTCOMES: A FOCUS ON MATERNAL NUTRITION Aulia, Bianda; Ermamilia, Aviria; Sundjaya, Tonny; Pratiwi, Dessy
Journal of Indonesian Specialized Nutrition Vol. 3 No. 2 (2025): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

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Abstract

Background: During pregnancy, maternal microbiota transfer and modifiable factors such as diet may contribute to fetal development. This review aims to clarify how maternal gut microbiota and diet interact to influence fetal nutrition and long-term health outcomes. Methods: A literature review was conducted on PubMed, Scopus, and Google Scholar. The search focused on studies investigating the links between maternal gut microbiota composition, dietary patterns, microbial metabolites, and fetal nutrition outcomes. Keywords included “pregnancy”, “gut microbiota”, “nutrition”, “maternal diet”, and “fetal growth”. Results: The maternal gut microbiota undergoes notable changes in late pregnancy, and its composition can be further influenced by external factors. Maternal diet and microbial transfer may impact fetal immune, metabolic, and neurodevelopment processes. Short-chain fatty acids and trimethylamine N-oxide are among key microbial metabolites implicated in fetal development. Although probiotic and prebiotic interventions during pregnancy show promise, current evidence remains limited and inconsistent across populations. Conclusion: Optimizing maternal gut microbiota through diet may support fetal nutrition and developmental outcomes. However, more longitudinal and ethnically diverse studies are needed.
OPTIMIZING IRON ABSORPTION IN CHILDREN THROUGH VITAMIN C SUPPLEMENTATION AND FORTIFICATION: A REVIEW Aulia, Bianda; Notarianti, Rizna; Larasati, Adisti; Sitorus, Nova Lidia
Journal of Indonesian Specialized Nutrition Vol. 3 No. 3 (2025): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v3i3.55

Abstract

Background: Iron deficiency aeamia is common in children, particularly in low- and middle-income countries, where diets are typically low in bioavailable iron and infections are prevalent. As vitamin C enhances non-heme iron absorption, this review explores current evidence on its role in improving iron status in children. Methods: A narrative literature review was conducted using PubMed, Scopus, and Google Scholar and included studies published from January 2000 to June 2025. Search terms combined keywords related to “vitamin C”, “iron absorption”, “supplementation”, “fortification”, “children”, and “anemia”. Results: Iron absorption in children is influenced by iron form, dietary factors, and developmental stage, with infants and young children at greatest risk of deficiency. Vitamin C is an enhancer of non-heme iron absorption, counteracting inhibitors such as phytates and calcium. Trials combining oral iron with vitamin C supplementation generally showed greater increases in hemoglobin and ferritin compared with iron alone, particularly among children with iron deficiency. Evidence from fortification studies is limited and varies due to differences in study design. Conclusion: Vitamin C co-supplementation might improve iron status in children. However, existing evidence remains insufficient to support specific recommendations for children.